Scienmag

APRIL 29, 2021

Now, in two related papers published April 28, 2021 in Science Translational Medicine, researchers at UCSF have demonstrated how to engineer […].

Clinical Trials 46

Clinical Trials Clinical Trials Engineer Trials 46

Scienmag

APRIL 22, 2021

In February, the researchers introduced […].

Production 84

Production Vaccination Vaccine Protein 84

Scienmag

SEPTEMBER 16, 2020

Research from the Texas A&M College of Engineering could lead to new approaches to treating viruses and cancers Credit: Dr. Wonmuk Hwang, Texas A&M University College of Engineering Research led by Dr. Wonmuk Hwang has led to better understanding on how components of the body’s immune system find intruding or damaged cells, which could (..)

Engineer 52

Engineer Research Allergies Medicine 52

XTalks

SEPTEMBER 21, 2023

This groundbreaking endeavor has received support from the National Institute of Allergy and Infectious Diseases (NIAID). These T cells are engineered to recognize various HIV proteins in a unique manner compared to previous experimental HIV vaccines.

Vaccination 59

Vaccination Vaccine Trials Clinical Trials 59

Scienmag

FEBRUARY 1, 2021

Houston Methodist and MD Anderson researchers collaborated on study in Nature Biomedical Engineering HOUSTON-(Feb.

Development 42

Development Engineer Drugs Research 42

Delveinsight

AUGUST 27, 2020

The phase 1 study that is being run by the National Institute of Allergy and Infectious Diseases tests three dose levels of the vaccine, mRNA-1273, given in two injections a month apart in 120 adults. Moderna showed robust phase 1 results for its COVID-19 vaccine in adults up to 55 last month.

Vaccination 53

Vaccination Vaccine Research Trials 53

Bioengineer

JULY 15, 2021

associate professor of human oncology in the University of Wisconsin School of Medicine and Public Health, and their colleagues designed a study to give mice with immunologically cold metastatic cancers varying doses of targeted radionuclide therapy alongside immunotherapy. About the University of Pittsburgh School of Medicine.

Medicine 52

Medicine Clinical Trials Clinical Trials Scientist 52

Scienmag

MARCH 24, 2021

Researchers at the Pritzker School of Molecular Engineering at the […]. But many cancer immunotherapy treatments can be expensive, have devastating side effects, and only work in a fraction of patients.

Engineer 40

Engineer Research Allergies Vaccination 40

Scienmag

FEBRUARY 2, 2021

” Their process enabled them to engineer two new, drug-like compounds that […].

Scientist 40

Scientist Engineer Drugs Research 40

The Pharma Data

DECEMBER 17, 2020

An Fc-engineered monoclonal antibody targeting the HER2 oncoprotein, MARGENZA offers hope for patients who have received two or more prior anti-HER2 regimens, with at least one being for metastatic disease. The new two-hour infusion time was previously approved by the European Medicines Agency (EMA) in May 2020.

FDA Approval 52

FDA Approval Genomics Genome Production 52

Scienmag

FEBRUARY 15, 2021

15, 2021 – By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

Antibody 40

Antibody Scientist Medicine Development 40

Scienmag

SEPTEMBER 9, 2020

Computer design of synthetic proteins is creating potent, stable antivirals that block infection at least as well as monoclonal antibodies Credit: Ian Haydon/UW Medicine Institute for Protein Design Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

Protein 40

Protein Antibody Medicine Allergies 40

Scienmag

JANUARY 4, 2021

In advance of public vaccination, a quick and accurate COVID-19 antibody test will help determine the presence of neutralizing antibodies, the molecules that aid in protection against the virus. Credit: UAB BIRMINGHAM, Ala.

Vaccination 98

Vaccination Vaccine Antibody Development 98

Pfizer

JANUARY 27, 2023

In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus.

Research 112

Research Vaccination Vaccine Drugs 112

Scienmag

NOVEMBER 17, 2020

Lysyl oxidase plays several important roles in promoting fibrosis in patients with scleroderma and is a potential biomarker of treatment response Credit: Sarah Pack, Medical University of South Carolina A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important (..)

Research 83

Research Allergies Engineer Development 83

Scienmag

APRIL 26, 2021

Susan Landau’s ‘People Count’ Credit: The MIT PRESS, 2021. How do you stop a pandemic before a vaccine arrives? Contact tracing is key, the first step in a process that has proven effective: trace, test, and isolate.

Vaccination 77

Vaccination Vaccine Allergies Engineer 77

Scienmag

JULY 12, 2021

Research highlights the critical role of the immune system in the aging process Researchers from the Buck Institute and Stanford University have created an inflammatory clock of aging (iAge) which measures inflammatory load and predicts multi-morbidity, frailty, immune health, cardiovascular aging and is also associated with exceptional longevity in (..)

Research 75

Research Bioinformatics Allergies Engineer 75

Scienmag

OCTOBER 22, 2020

Credit: © 2020 KAUST; Heno Hwang A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants. Cord blood is currently used to treat more than 80 life-threatening conditions, ranging from cancer and immune deficiency to metabolic and genetic disorders.

Genetics 69

Genetics Allergies Engineer Medicine 69

Scienmag

MARCH 1, 2021

Credit: Earlham Institute Respiratory viruses such as SARS-CoV-2 (causing COVID-19) can often catalyse an overactive immune response that leads to a life-threatening cycle, known as a cytokine storm.

Immune Response 59

Immune Response Bioinformatics Allergies Genetics 59

Scienmag

FEBRUARY 23, 2021

Viruses make copies of themselves during an infection, and new research sheds light on one of the coronavirus molecules that is important for this process, providing a potential drug target that could work for Covid-19 and other coronavirus outbreaks too. Credit: Image courtesy of Keith Mickolajczyk.

Drugs 61

Drugs Research Allergies Genetics 61

Scienmag

AUGUST 7, 2020

A new study concludes that opening clinics dedicated specifically to treating influenza can limit the number of people infected and help to “flatten the curve,” or reduce the peak prevalence rate. “Dedicated clinics […].

Allergies 61

Allergies Engineer Medicine 61

Scienmag

OCTOBER 19, 2020

Garrido, CNIO The sophisticated human immune system has evolved to become an effective protection system against a great number of diseases, cancer being one of them. The immune system recognises and destroys cancer cells using a monitoring process called immunological surveillance.

Dermatology 52

Dermatology Allergies Gene Genetics 52

Scienmag

SEPTEMBER 10, 2020

New book for the general public explains how novel viruses such as SARS-Cov-2 emerge and how we can fight them Credit: MIT ChemE CAMBRIDGE, MA — Since the novel coronavirus SARS-Cov-2 emerged late last year, it has been virtually impossible to consume any news without encountering stories about the virus and how it spreads, potential […]. (..)

Vaccination 52

Vaccination Vaccine Allergies Engineer 52

Scienmag

MARCH 28, 2021

Newly-published “contact lens technologies of the future” paper reviews innovative uses for disease detection and therapy, drug delivery, vision enhancement and mor Credit: Centre for Ocular Research & Education (CORE) WATERLOO, Ontario, March 29, 2021–A newly-published paper represents one of the most comprehensive reviews of (..)

Drug Delivery 52

Drug Delivery Research Drugs Allergies 52

Scienmag

FEBRUARY 25, 2021

Research from the California Institute of Technology shows exactly how antibodies stick to and block the Zika virus, which will inform vaccine development Credit: Image courtesy of Shannon Esswein.

Antibody 52

Antibody Scientist Vaccination Vaccine 52

Scienmag

OCTOBER 19, 2020

A new chemistry technique expands known targets of signaling protein galectin-3, with implications for liver disease and the immune system Credit: Scott Wiseman for Scripps Research October 19, 2020 JUPITER, FL–Human cells are encased by a membrane coated with diverse sugar molecules known as glycans.

Protein 52

Protein Research Allergies Engineer 52

Scienmag

MARCH 19, 2021

Delivering vaccines directly to the lungs can boost immune responses to respiratory infections or lung cancer, study finds. CAMBRIDGE, MA — Many viruses infect their hosts through mucosal surfaces such as the lining of the respiratory tract.

Vaccination 48

Vaccination Vaccine Immune Response Development 48

Scienmag

OCTOBER 27, 2020

New study of older adults (aged 70 or over) in Stockholm, Sweden, suggests older people living in care homes had higher COVID-19 mortality risk than those living in single houses or apartment buildings Peer-reviewed / Observational study / People New study of older adults (aged 70 or over) in Stockholm, Sweden, suggests older people living […]. (..)

Gerontology 50

Gerontology Allergies Engineer Medicine 50

Scienmag

JANUARY 12, 2021

Boosting a natural cellular process could reduce damage, study suggests COLUMBUS, Ohio – An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung damage.

Scientist 41

Scientist Allergies Engineer Medicine 41

Scienmag

OCTOBER 7, 2020

With computer models and lab experiments, researchers are working on a strategy for vaccines that could protect against any influenza virus Each year, the flu vaccine has to be redesigned to account for mutations that the virus accumulates, and even then, the vaccine is often not fully protective for everyone.

Vaccination 40

Vaccination Vaccine Research Allergies 40

Scienmag

SEPTEMBER 15, 2020

Molecular clock analysis showed no widespread ‘community’ distribution of the highly contagious coronavirus disease in Arizona until mid-February FLAGSTAFF, Ariz. — Sept.

Genomics 40

Genomics Genome Allergies Genetics 40

Scienmag

OCTOBER 16, 2020

University of New Mexico researchers find existing medications may fight coronavirus infection University of New Mexico researchers who combed through a “library” of previously approved drugs believe they have identified a medication with the potential to help speed a patient’s recovery from SARS-CoV-2 infection.

Drugs 40

Drugs Research Allergies Engineer 40

Scienmag

DECEMBER 22, 2020

Around a third of the world’s population carries Toxoplasma gondii, a parasite that puts people with a weakened immune system at risk and can trigger malformations in the womb. The single-celled pathogen also leads to economic losses in agriculture, with toxoplasmosis increasing the risk of abortion among sheep, for example.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Allergies 40

XTalks

DECEMBER 24, 2020

In addition to pharma and biotech companies who zealously began working to develop COVID-19 drugs and vaccines, companies from areas outside of science and medicine also stepped up to help during the pandemic. The study was published this month in the New England Journal of Medicine. Vaccine Considerations.

Life Science 111

Life Science Vaccination Vaccine Gene 111

XTalks

SEPTEMBER 14, 2020

These companies include Moderna, a US biotech company which has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID), Oxford University who has partnered with AstraZeneca, and Johnson & Johnson, Merck and Pfizer. Brazil has the second worst outbreak in the world, as it is now reporting over 1.8

Vaccination 92

Vaccination Vaccine Antibody Life Science 92