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LJI scientists track down control elements that govern geneexpression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. “The difference is within us,” says Vivek Chandra, Ph.D.,
First study to show geneexpression changes in divers with ‘the bends’ reveals key role of genes for inflammation and immunity For over a century, researchers have known about “the bends”, a serious condition affecting scuba divers. However, we still know relatively little about its physiological basis.
The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We BacTRL Gene Therapy Platform.
According to a study, around 20,000 genes are present in the human body, all of which interact with the nutrients in the food, either directly or indirectly. Nutritional DNA testing helps in identifying foods that might lead to allergies or intolerance in an individual. Figure below presents an overview of nutrigenomics.
Ann Allergy Asthma Immunol. World Allergy Organization (WAO). EMJ Allergy Immunol. Measures of geneexpression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. Explor Res Hypothesis Med. 2019;4:35-38. Tran TN, et al. 2016;116:37-42. Chung KF, et al. Eur Respir J.
10 World Allergy Organization (WAO). EMJ Allergy Immunol. Measures of geneexpression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. J Allergy Clin Immunol. Asthma control and management in 8,000 European patients: the Recognise Asthma and Link to Symptoms and Experience (REALISE) survey.
From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.
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