Scienmag

MAY 11, 2021

An international team of researchers at Great Ormond Street Hospital (GOSH), and University of California, Los Angeles (UCLA) have developed a gene therapy that successfully treated 48 out of 50 children with a form of severe combined immunodeficiency that leaves them without an immune system.

Gene Therapy 73

Gene Therapy Gene Development Research 73

Scienmag

DECEMBER 21, 2020

Researchers baffled by an infant’s rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the ‘immunity gene’ Credit: Satoshi Okada An infant’s odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate (..)

Gene 52

Gene Genetics Research Allergies 52

Scienmag

OCTOBER 29, 2020

USF Health-led TEDDY analysis focuses on development of multiple distinct autoantibodies targeting insulin-producing cells, from initial autoimmunity to symptomatic type 1 diabetes Credit: Courtesy of USF Health TAMPA, Fla.

Genetics 92

Genetics Insulin Development Clinical Trials 92

Scienmag

DECEMBER 21, 2020

LJI scientists track down control elements that govern gene expression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. “The difference is within us,” says Vivek Chandra, Ph.D.,

Gene Expression 52

Gene Expression Gene Genetics Scientist 52

Scienmag

APRIL 16, 2021

– April 16, 2021 – Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Credit: Dotted Yeti LA JOLLA, CALIF.

Gene 60

Gene Scientist Research Allergies 60

XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We BacTRL Gene Therapy Platform.

Clinical Trials 75

Clinical Trials Clinical Trials Vaccine Vaccination 75

Scienmag

DECEMBER 13, 2020

In this type of therapy, T cells, a type of white blood cell, are collected from a patient’s blood and subjected to genetic engineering to produce T cells carrying a synthetic molecule termed chimeric antigen receptor (CAR) […].

Genetic Engineering 95

Genetic Engineering Engineer Genetics Allergies 95

pharmaphorum

FEBRUARY 16, 2022

She received a cord blood transplant to treat the AML, receiving stem cells carrying a genetic mutation (CCR?5/?32) Having a third functional cure of HIV nevertheless does give pointers to how a more widely applicable cure might be developed in the future, for example using gene-editing drugs to introduce CCR5?32

Gene Editing 69

Gene Editing Research Gene Genetics 69

Scienmag

OCTOBER 25, 2020

Jänne New results from early clinical trials of a drug that targets a cancer-causing mutation in the KRAS gene have shown that it can shrink tumours and is well-tolerated by patients. Latest results from KRYSTAL-1 early clinical trial of adagrasib (MRTX849) Credit: Pasi A.

Gene 53

Gene Clinical Trials Clinical Trials Trials 53

XTalks

JULY 26, 2021

Those who seek shorter ingredient lists and cleaner labels may object to plant-based meat due to the many additives and genetically modified proteins that tend to be crucial components of its formulation. For example, the Allergen Bureau indicated a possible connection between pea protein and peanut allergies. FDA Regulation.

Protein 98

Protein Contamination Allergies Bacteria 98

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

XTalks

NOVEMBER 30, 2023

More Investigational Therapies for HIV Are on the Way American Gene Technologies, a pioneering biotech company headquartered in Rockville, Maryland, has released promising results from its Phase I trial of AGT103-T, a gene therapy designed for individuals with chronic HIV disease.

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FDA Approval Gene Therapy Gene Clinical Trials 111

The Pharma Data

AUGUST 7, 2020

As the pharma industry stands firm in its commitment to advance the sector to fight Covid-19, news has emerged from the European Commission who intend to streamline the development of therapies using genetically modified organisms to treat Covid-19. Regenerative medicine and advanced therapies thriving despite Covid-19 disruption.

Clinical Trials 52

Clinical Trials Clinical Trials Gene Trials 52

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccine 52

Vaccine Vaccination DNA Protein 52

Scienmag

FEBRUARY 1, 2021

According to a study published in Frontiers in Immunology, the reason is their genetic heterogeneity and lack of proportional representation in the Brazilian bone marrow bank Credit: Diogo Meyer A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National (..)

Genetics 65

Genetics Scientist Allergies Gene 65

Scienmag

NOVEMBER 25, 2020

First and corresponding author Dr Lucy van Dorp (UCL Genetics […]. The analysis of virus genomes from over 46,000 people with COVID-19 from 99 countries is published today in Nature Communications.

Genomics 58

Genomics Genome Genetics Research 58

Roots Analysis

AUGUST 31, 2023

According to a study, around 20,000 genes are present in the human body, all of which interact with the nutrients in the food, either directly or indirectly. Nutritional DNA testing helps in identifying foods that might lead to allergies or intolerance in an individual. Figure below presents an overview of nutrigenomics.

Genome 40

Genome Genomics Genetics Gene 40

Scienmag

OCTOBER 9, 2020

Findings could lay the foundation for the development of effective therapeutic and malaria vaccine strategies, which has largely been hindered by a lack of understanding of the host immune response Credit: Aissatou Diawara Abu Dhabi, UAE, October 9, 2020: The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers (..)

Immune Response 52

Immune Response Gene Research Vaccination 52

The Pharma Data

FEBRUARY 22, 2021

Gene editing investments advance agriculture with improved food quality, higher yield, and improved crop nutrition. Gene editing is the key to better solutions and greater choices for farmers and consumers around the world. In crop science that means a transformative opportunity to improve yield and simplify harvesting for farmers.

Gene Editing 40

Gene Editing Genomics Genome Protein 40

Scienmag

OCTOBER 12, 2020

Mouse immune study gives pointers for development of vaccines and immune therapies Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

Gene 40

Gene Vaccination Vaccine Development 40

Scienmag

JUNE 20, 2021

Researchers shed light on a potential intervention that could make tumors responsive to modern-day immunotherapies Credit: Mei Huang, PhD BOSTON – Researchers from Massachusetts General Hospital (MGH) have discovered a biological mechanism that transforms cells exposed to carcinogens from environmental factors like smoking and ultraviolet light (..)

Research 98

Research Allergies Gene Genetics 98

Scienmag

JULY 14, 2021

Scientists report that the alternative-splicing regulator NSrp70 influences immune T cell development Credit: Gwangju Institute of Science & Technology T lymphocytes, or T cells, are immune cells with diverse roles in building the body’s immunity. How does one particular cell type fight against a host of different pathogens?

Scientist 98

Scientist Regulation Development Allergies 98

The Pharma Data

JULY 8, 2021

This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Ann Allergy Asthma Immunol. World Allergy Organization (WAO). EMJ Allergy Immunol. J Allergy Clin Immunol. Explor Res Hypothesis Med. 2019;4:35-38. Eur Respir J.

Allergies 52

Allergies Trials In-Vivo Medicine 52

The Pharma Data

MAY 13, 2021

The REAL problem lies in the fact that most of the foods we eat today have been Genetically Modified. food is “A food in which the gene from one species has been forced into the DNA of another species and the process itself creates all sorts of unpredicted side effects.”. A better definition of a G.M.O. When lab rats were given G.M.O.

Production 52

Production Containment Genetics Doctor 52

XTalks

DECEMBER 20, 2023

The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy. Bayer’s Astepro (azelastine), an over-the-counter medication for cold, flu and allergies, led the pack in the first half of 2023 with 7.4 billion ad impressions.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

Scienmag

NOVEMBER 24, 2020

Credit: Salk Institute LA JOLLA–(November 24, 2020) Salk Professors Susan Kaech and Alan Saghatelian have been named 2020 Fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the journal Science.

Allergies 62

Allergies Gene Genetics Vaccination 62

Scienmag

JANUARY 6, 2021

Research team determines that the “Immune only” focus of current research must be updated to better understand autoimmune diseases such as type 1 diabetes and multiple sclerosis Credit: Indiana Biosciences Research Institute Indianapolis, Ind.

Research 60

Research Allergies Gene Genetics 60

Scienmag

FEBRUARY 11, 2021

MUSC Hollings Cancer Center researcher finds loss of STING in recipient dendritic cells increases GVHD severity Credit: MUSC Hollings Cancer Center MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

Research 53

Research Gene Therapy Allergies Gene 53

Scienmag

OCTOBER 19, 2020

Garrido, CNIO The sophisticated human immune system has evolved to become an effective protection system against a great number of diseases, cancer being one of them. The immune system recognises and destroys cancer cells using a monitoring process called immunological surveillance.

Dermatology 52

Dermatology Allergies Gene Genetics 52

The Pharma Data

NOVEMBER 9, 2020

This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. 10 World Allergy Organization (WAO). EMJ Allergy Immunol. Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma. 11 Busse WW.

Trials 52

Trials Production Sales Manufacturing 52

XTalks

DECEMBER 24, 2020

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.

Life Science 111

Life Science Vaccination Vaccine Gene 111

Scienmag

APRIL 19, 2021

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

Gene 44

Gene Medicine Research Allergies 44

XTalks

SEPTEMBER 14, 2020

These companies include Moderna, a US biotech company which has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID), Oxford University who has partnered with AstraZeneca, and Johnson & Johnson, Merck and Pfizer.

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Vaccination Vaccine Antibody Life Science 92