Scienmag

JUNE 27, 2021

A new vaccine to protect against deadly cholera has been made by grinding up genetically modified grains of rice. The first human trial has shown no obvious side effects and a good immune response. Study points towards role of gut microbiome in vaccine effectiveness Credit: Image by Dr. Hiroshi Kiyono, CC BY 4.0

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Scienmag

SEPTEMBER 15, 2020

Credit: Michigan State University Differences in biological sex can dictate lifelong disease patterns, says a new study by Michigan State University researchers that links connections between specific hormones present before and after birth with immune response and lifelong immunological disease development.

Hormones 78

Hormones Immune Response Development Research 78

XTalks

NOVEMBER 30, 2023

This candidate, derived from a person’s own genetically modified cells, aims to restore the Gag-specific CD4+ T cell response in those receiving antiretroviral therapy. In November 2023, Hookipa Pharma Inc., Notably, it significantly reduced viral load and clinical illness compared to a placebo.

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FDA Approval Gene Therapy Gene Clinical Trials 111

pharmaphorum

FEBRUARY 28, 2021

“Importantly, the vaccine was 100 percent effective in protecting against death from the disease everywhere it was tested,” commented Anthony Fauci, director of the National Institute for Allergy & Infectious Disease (NIAID). “To The vaccine causes the body to create its own copies of the protein, stimulating an immune response.

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Scienmag

MARCH 1, 2021

Credit: Earlham Institute Respiratory viruses such as SARS-CoV-2 (causing COVID-19) can often catalyse an overactive immune response that leads to a life-threatening cycle, known as a cytokine storm.

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Immune Response Bioinformatics Allergies Genetics 59

The Pharma Data

JULY 8, 2021

Specifically, tezepelumab targets and blocks thymic stromal lymphopoietin (TSLP), a key epithelial cytokine that sits at the top of multiple inflammatory cascades and initiates an overreactive immune response to allergic, eosinophilic and other types of airway inflammation associated with severe asthma.(24,25). EMJ Allergy Immunol.

Allergies 52

Allergies Trials In-Vivo Medicine 52

The Pharma Data

MARCH 13, 2022

That’s because the mutations that led to the variant’s emergence aren’t found in the regions of the virus that stimulates one type of cellular immune response, says an international research team from Johns Hopkins Medicine, in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) and ImmunoScape, a U.S.-Singapore

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Immune Response Protein Medicine Genetics 52

Scienmag

OCTOBER 9, 2020

Findings could lay the foundation for the development of effective therapeutic and malaria vaccine strategies, which has largely been hindered by a lack of understanding of the host immune response Credit: Aissatou Diawara Abu Dhabi, UAE, October 9, 2020: The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers (..)

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Immune Response Gene Research Vaccine 52

Scienmag

JUNE 25, 2021

Changes to the ‘spike’ protein explain Alpha’s faster spread, and how the Beta variant evades immune responses, suggesting the need for a booster with an updated vaccine Credit: Bing Chen, PhD, Boston Children’s Hospital New SARS-CoV-2 variants are spreading rapidly, and there are fears that current COVID-19 vaccines won’t (..)

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The Pharma Data

DECEMBER 31, 2020

The vaccine teaches the cells to make a piece of the spike protein, which triggers an immune response to help prevent illness if later exposed to the virus. These reactions can be treated, and most patients with allergies can still get the vaccine. Hereditary angioedema (HAE) is a rare but serious genetic immune system disorder.

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Vaccine Vaccination FDA Approval Hormones 52

The Pharma Data

MAY 13, 2021

Preliminary data obtained through genetic sequencing suggest that the new outbreak was caused by the same virus strain also responsible for the 2014-2016 outbreak and was likely reintroduced by a survivor. In addition, these vectors carry the genetic code of several Ebola virus proteins in order to trigger an immune response.

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Vaccine Vaccination Medicine Clinical Trials 52

The Pharma Data

DECEMBER 31, 2020

National Institute of Allergy and Infectious Diseases, Gov. Topol said that the United States does less genetic sequencing of virus to discover variants than other nations, and thus was probably slow to detect this new mutation. In an online conference with Dr. Anthony Fauci, head of the U.S.

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Vaccine Vaccination Genetics Protein 52

XTalks

SEPTEMBER 14, 2020

These companies include Moderna, a US biotech company which has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID), Oxford University who has partnered with AstraZeneca, and Johnson & Johnson, Merck and Pfizer. China’s COVID-19 Vaccine: Sinovac Biotech and CanSino Biologics.

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Vaccine Vaccination Antibody Life Science 92