Scienmag

MARCH 25, 2021

– Researchers have found an unexpected synergy between a T-cell stimulatory protein — the ICOS ligand — and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice. This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6

Protein 91

Protein Research Allergies Medicine 91

Pharmaceutical Technology

JUNE 28, 2022

grant from the National Institutes of Health (NIH) unit National Institute of Allergy and Infectious Diseases (NIAID) for developing a Covid-19 oral antiviral drug. The Rensselaer team will partner with researchers from the Scripps Research Institute, Mount Sinai School of Medicine and the University of Bologna, Italy for this research.

Development 147

Development Bioinformatics Drugs Allergies 147

Scienmag

AUGUST 17, 2020

Rutgers researchers discovered a new role the protein may have in helping to treat allergies, asthma, COPD A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

Protein 40

Protein Allergies Research Medicine 40

Scienmag

OCTOBER 14, 2020

Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction, supports a mechanism critical for survival in mouse models of sepsis and colitis Credit: UC San Diego Health Sciences The immune response to infections is a delicate balance.

Protein 67

Protein Immune Response Bacteria Allergies 67

Scienmag

APRIL 22, 2021

In February, the researchers introduced […].

Production 84

Production Vaccine Vaccination Protein 84

Scienmag

SEPTEMBER 9, 2020

Computer design of synthetic proteins is creating potent, stable antivirals that block infection at least as well as monoclonal antibodies Credit: Ian Haydon/UW Medicine Institute for Protein Design Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

Protein 40

Protein Antibody Medicine Allergies 40

Scienmag

JULY 15, 2021

A new protein-based vaccine candidate combined with a potent adjuvant provided effective protection against SARS-CoV-2 when tested in animals, suggesting that the combination could add one more promising COVID-19 vaccine to the list of candidates for human use.

Protein 52

Protein Vaccine Vaccination Allergies 52

Scienmag

JULY 23, 2021

Antibodies capable of neutralizing multiple SARS-CoV-2 strains can inform strategies for broadly protective COVID-19 booster vaccines As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions (..)

Antibody 75

Antibody Protein Vaccine Vaccination 75

The Pharma Data

JANUARY 6, 2021

(“CytoDel” or “the Company”), a privately-held corporation, today announces the publication of preclinical data on the Company’s lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. Cyto-111 was conceived, expressed and purified in the laboratory of Konstantin Ichtchenko, Ph.D., Südhof, M.D.,

Medicine 52

Medicine Antibody Protein In-Vitro 52

Scienmag

MARCH 4, 2021

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

Protein 54

Protein Allergies Vaccination Vaccine 54

Scienmag

OCTOBER 6, 2020

— Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system. HERSHEY, Pa.

Immune Response 40

Immune Response Protein Medicine Research 40

Scienmag

APRIL 22, 2021

SARS-CoV-2 can recruit a haem metabolite to evade antibody immunity Researchers have identified another potential target for neutralizing antibodies on the SARS-CoV-2 Spike protein that is masked by metabolites in the blood.

Antibody 46

Antibody Protein Scientist Research 46

The Pharma Data

JANUARY 11, 2021

They give the body a blueprint to create a bit of the virus that causes COVID-19, called a spike protein. Once you are vaccinated, the cell’s machinery uses the blueprint to make the spike protein. This protein then appears on the surface of the cell and the immune system responds to it.

Vaccine 52

Vaccine Vaccination Allergies Protein 52

Scienmag

JUNE 30, 2021

A 7- to 15-year longitudinal study of 358 diabetics has linked 3 proteins in blood with a slower progression of diabetic kidney disease and progressive kidney failure.

Protein 40

Protein Research Allergies Medicine 40

Scienmag

SEPTEMBER 28, 2020

29, 2020 – A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular structure and sequence of the SARS-CoV-2 spike protein–part of the virus that causes […].

Protein 64

Protein Medicine Development Research 64

XTalks

SEPTEMBER 8, 2020

“Our experience in drug product fill/finish will enable timely manufacturing to make the vaccine available as soon as possible to advance bringing life-changing medicines to market.”. The genetic material contains SARS-CoV-2 spike protein. Fauci, in a statement. The Phase 3 trial is being implemented as part of Operation Warp Speed.

Manufacturing 83

Manufacturing Vaccine Vaccination Allergies 83

Scienmag

JULY 6, 2021

Studies reveal unprecedented mechanism behind loss of antibody neutralization against this pandemic coronavirus variant of concern Credit: Young-Jun Park, UW Department of Biochemistry Three mutations in the Epsilon coronavirus spike protein dampen the neutralizing potency of antibodies induced by current vaccines or past COVID infections.

Antibody 98

Antibody Protein Vaccine Vaccination 98

Scienmag

AUGUST 20, 2020

aureus) proteins protects mice against S. Credit: NIAID Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus (S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens by David Underhill of Cedars-Sinai Medical Center, and colleagues.

Vaccine 98

Vaccine Vaccination Protein Allergies 98

Scienmag

AUGUST 11, 2020

Antibody that blocks TREM2 protein frees immune cells to reject cancer Credit: William Vermi/Martina Molgora Immunotherapy has revolutionized cancer treatment by stimulating the patient’s own immune system to attack cancer cells, yielding remarkably quick and complete remission in some cases.

Protein 95

Protein Antibody Drugs Allergies 95

Scienmag

NOVEMBER 16, 2020

Cincinnati Children’s team reports controlling the BCAP protein could slow overactive immune response in IBD, rheumatoid arthritis or accelerate response against tumors Credit: Cincinnati Children’s Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new (..)

Immune Response 78

Immune Response Protein Allergies Medicine 78

Scienmag

OCTOBER 14, 2020

Animal study shows treatment blocks inflammation and protects lungs without killing the flu virus COLUMBUS, Ohio – The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.

Protein 40

Protein Drugs Allergies Medicine 40

Scienmag

APRIL 9, 2021

The structural revelation could have implications as a therapeutic target in all SARS-CoV-2 variants Credit: Kelly Lab/Penn State A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers.

Antibody 93

Antibody Protein Scientist Research 93

Scienmag

DECEMBER 9, 2020

A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies.

Protein 75

Protein Genetics Allergies Vaccination 75

Scienmag

JUNE 14, 2021

A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer’s disease, a new study shows.

Protein 56

Protein Medicine Research Allergies 56

Scienmag

JUNE 22, 2021

New research published in the Journal of Cellular and Molecular Medicine indicates that SARS-CoV-2, the virus that causes COVID-19, produces microRNAs that can have impacts on infected cells. Investigators found that the […].

Protein 42

Protein Genetics Medicine Production 42

Scienmag

JUNE 25, 2021

Changes to the ‘spike’ protein explain Alpha’s faster spread, and how the Beta variant evades immune responses, suggesting the need for a booster with an updated vaccine Credit: Bing Chen, PhD, Boston Children’s Hospital New SARS-CoV-2 variants are spreading rapidly, and there are fears that current COVID-19 vaccines won’t (..)

Immune Response 75

Immune Response Vaccine Vaccination Protein 75

Scienmag

JUNE 6, 2021

New resource for neuroscience maps cell types, secreted proteins, spatial organization, and more Credit: Dani N, Herbst RH, et al. Cell April 30, 2021, DOI 10.1016/j.cell.2021.04.003. 2021.04.003.

Protein 72

Protein Allergies Medicine 72

Druggist

FEBRUARY 17, 2021

Hydrocortisone cream is classified as pharmacy-only medicine (P), which means it can only be sold in pharmacies, including online chemists and sellers on Amazon.co.uk. Anthisan Cream contains a medicine called mepyramine maleate. Patients on certain medicines may not be able to use Lanacane cream. Rashes caused by allergies .

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Pharmacy Containment Production Sales 98

The Pharma Data

MARCH 13, 2022

That’s because the mutations that led to the variant’s emergence aren’t found in the regions of the virus that stimulates one type of cellular immune response, says an international research team from Johns Hopkins Medicine, in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) and ImmunoScape, a U.S.-Singapore

Immune Response 52

Immune Response Protein Medicine Genetics 52

Scienmag

MARCH 15, 2021

The first vaccine has been administered in a comparative adjuvant trial of DNA prime/protein boost HIV vaccine regimens in Kericho, Kenya Credit: U.S. Military HIV Research Program SILVER SPRING, Md.

Vaccine 68

Vaccine Vaccination Trials DNA 68

pharmaphorum

AUGUST 12, 2021

It binds to a site on a parasite surface protein that seems to be important for infection and – crucially – is found on all worldwide variants of Plasmodium falciparum, the organism that causes the most severe form of malaria.

Antibody 64

Antibody Vaccine Vaccination Allergies 64

Scienmag

OCTOBER 23, 2020

The technique should help in the design of vaccines against HIV, SARS-CoV-2 and other viruses that cloak their outer proteins with sugars to evade antibodies.

Protein 61

Protein Antibody Scientist Vaccine 61

Delveinsight

AUGUST 27, 2020

The phase 1 study that is being run by the National Institute of Allergy and Infectious Diseases tests three dose levels of the vaccine, mRNA-1273, given in two injections a month apart in 120 adults. The BET inhibitor worked by increasing beta-3 tubulin (TUBB3), a protein found in brain metastases.

Vaccine 53

Vaccine Vaccination Research Trials 53

XTalks

SEPTEMBER 16, 2024

HAE is caused by a deficiency or dysfunction of the C1-inhibitor, a protein involved in regulating inflammation. Cinryze, Haegarda) used to replace the deficient or dysfunctional C1 inhibitor protein in the blood, helping to prevent the inflammatory processes that cause angioedema.

Protein 52

Protein Genetics Trials Allergies 52

Scienmag

MAY 13, 2021

The new […].

Immune Response 53

Immune Response Antibody Protein Vaccine 53

Druggist

SEPTEMBER 15, 2021

During the treatment of covid-19, some medicines were also given for prevention. These medicines are used to prevent bacterial infection. Recently research has revealed that these medicines doxycycline and azithromycin given to covid patients is not effective in dangerous infection. This medicine depends on the case.

Doctor 52

Doctor Doctors Medicine Bacteria 52

Druggist

SEPTEMBER 15, 2021

During the treatment of covid-19, some medicines were also given for prevention. These medicines are used to prevent bacterial infection. Recently research has revealed that these medicines doxycycline and azithromycin given to covid patients is not effective in dangerous infection. This medicine depends on the case.

Doctor 52

Doctor Doctors Medicine Bacteria 52