pharmaphorum

MARCH 23, 2021

AstraZeneca has been rebuked by a US health authority after a trial monitoring board said data published from a large study of its COVID-19 vaccine may be out of date and may not give a representative view of its efficacy. AstraZeneca is preparing to file this and other trial data with the FDA asking for an emergency approval of the vaccine.

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Scienmag

SEPTEMBER 30, 2020

Credit: Stefan Zimmerman Women vaccinated against HPV have a significantly lower risk of developing cervical cancer, and the positive effect is most pronounced for women vaccinated at a young age. That is according to a large study by researchers at Karolinska Institutet in Sweden published in New England Journal of Medicine.

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Vaccine Vaccination Medicine Development 97

Pfizer

SEPTEMBER 28, 2022

Pfizer and BioNTech Complete Submission to European Medicines Agency for Omicron BA.4/BA.5-Adapted 5-Adapted Bivalent Vaccine Booster in Children 5 Through 11 Years of Age. Pfizer and BioNTech Complete Submission to European Medicines Agency for Omicron BA.4/BA.5-Adapted 5-adapted bivalent vaccine. 5) AUTHORIZED USES .

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Vaccine Vaccination Medicine Clinical Trials 101

Pharmaceutical Technology

AUGUST 5, 2022

It is ultra-rare,” says Jesús Rodriguez Requena, PhD, associate professor in the Department of Medicine at the University of Santiago de Compostela. There is an enormous emphasis on prion protein and prion protein folding,” says Dr. Laura Manuelidis, professor of neuropathology at the Yale School of Medicine. “If

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Scienmag

OCTOBER 5, 2020

Michael Houghton discovered hepatitis C virus and now is developing a vaccine Credit: Photo: Michael Holly Michael Houghton was awarded the 2020 Nobel Prize in Physiology or Medicine today in recognition of his discovery of the hepatitis C (HCV) virus.

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Medicine Vaccine Vaccination Development 86

XTalks

SEPTEMBER 8, 2020

The company has signed on to help manufacture AstraZeneca’s COVID-19 vaccine candidate, AZD1222, intended to protect against the SARS-CoV-2 novel coronavirus. AMRI is proud to partner with AstraZeneca in pursuit of a vaccine that could protect people against the coronavirus pandemic,” said John Ratliff, CEO of AMRI, in a statement.

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Manufacturing Vaccine Vaccination Allergies 83

Pfizer

JULY 26, 2022

Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design. Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design. deliesschef.

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Vaccine Vaccination Protein Immune Response 111

Scienmag

JULY 13, 2021

Study suggests spatial relationship between COVID-19 mortality and population-level health factors Credit: Kandula S and Shaman J, 2021, PLOS Medicine COVID-19 vaccination strategies in the United States are informed by individual characteristics such as age and occupation.

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Vaccination Vaccine Medicine Allergies 81

Scienmag

APRIL 22, 2021

In February, the researchers introduced […].

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Production Vaccination Vaccine Protein 84

Scienmag

JULY 23, 2021

Intranasal vaccination is needle-free and elicits immunity at the site of infection, the respiratory tract Credit: UAB BIRMINGHAM, Ala. and Troy Randall, Ph.D., write […].

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Vaccine Vaccination Clinical Trials Clinical Trials 98

Scienmag

JANUARY 4, 2021

In advance of public vaccination, a quick and accurate COVID-19 antibody test will help determine the presence of neutralizing antibodies, the molecules that aid in protection against the virus. Credit: UAB BIRMINGHAM, Ala.

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Vaccine Vaccination Antibody Development 98

XTalks

FEBRUARY 24, 2025

Carlsbad, California-based Ionis Pharmaceuticals announced it will be sharing promising new trial data for its RNA-targeted prophylactic treatment donidalorsen for hereditary angioedema (HAE) at the 2025 American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress in San Diego, California.

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Trials RNA Allergies Drugs 59

Scienmag

NOVEMBER 9, 2020

— Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published November 9 in the open-access journal PLOS […]. UNIVERSITY PARK, Pa.

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Vaccine Vaccination Bacteria Development 98

Scienmag

OCTOBER 14, 2020

A prospective observational study testing the concept of trained immunity for protection from severe COVID-19 reported milder symptoms in COVID patients receiving MMR vaccination, as published in Allergy. Yet what if an existing vaccine […].

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Vaccine Vaccination Allergies Clinical Trials 59

Scienmag

AUGUST 20, 2020

Credit: NIAID Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus (S. aureus) proteins protects mice against S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens by David Underhill of Cedars-Sinai Medical Center, and colleagues.

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Vaccination Vaccine Protein Allergies 98

Pfizer

JULY 8, 2022

FDA Approval of their COVID-19 Vaccine COMIRNATY® For Adolescents 12 through 15 Years of Age. FDA Approval of their COVID-19 Vaccine COMIRNATY® For Adolescents 12 through 15 Years of Age. The vaccine was previously made available to this age group in the U.S. Fri, 07/08/2022 - 11:48. Pfizer and BioNTech Announce U.S.

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FDA Approval Vaccine Vaccination Clinical Trials 102

DM Clinical Research

APRIL 30, 2021

And while this means that most of us can get outside and enjoy the nice weather, it means something different to allergy sufferers. If you have seasonal allergies, then you know how painful and annoying your symptoms can be. Certain symptoms might have you wondering- is it allergies or COVID? Is it Allergies or COVID symptoms?

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Allergies Clinical Research Vaccination Vaccine 40

The Pharma Data

JANUARY 11, 2021

11, 2021 — As the rollout of the COVID-19 vaccines continues, scores of questions are emerging. How do the COVID-19 vaccines work? The COVID-19 vaccines work by teaching the immune system to protect against the virus, experts said. ” Can the vaccines make you sick? Once vaccinated, can I get rid of the masks?

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Vaccine Vaccination Allergies Protein 52

Scienmag

NOVEMBER 4, 2020

The finding provides a surrogate for testing the effectiveness of vaccine candidates Credit: Jennifer Jenks, Duke University School of Medicine DURHAM, N.C.

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Vaccine Vaccination Research Development 63

Scienmag

SEPTEMBER 3, 2020

A team at the George Washington University Vaccine Research Unit has developed a controlled human hookworm infection model, accelerating the development of human hookworm vaccines WASHINGTON (August 26, 2020) – A team led by researchers at the George Washington University (GW) has established a controlled human hookworm infection (CHHI) model (..)

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Vaccine Vaccination Research Development 68

Scienmag

OCTOBER 2, 2020

Credit: Virginia Tech Renowned tick immunobiologist Utpal Pal wants to ad apt the rabies vaccination platform to produce antibodies that can protect against Borrelia burgdorferi, the bacteria responsible for Lyme disease. The intention is to apply this work to other tick-borne diseases in the future.

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Vaccination Vaccine Bacteria Development 88

Scienmag

MAY 26, 2021

Meta-analysis updates findings about common vaccines A new study looking across a large body of research finds further evidence for the safety of vaccines that are Food and Drug Administration-approved and routinely recommended for children, adults and pregnant women.

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Vaccine Vaccination Drugs Research 75

Pharmaceutical Technology

JUNE 9, 2023

After a long period without any new approvals, in May, the FDA approved GSK’s vaccine Arexvy for the prevention of LRTD caused by RSV in individuals 60 and older. On 31 May, the FDA also approved Pfizer’s vaccine Abrysvo in the same patient population.

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Scienmag

OCTOBER 11, 2020

A largescale global trial designed to test the theory that the widely-used BCG vaccine could help protect against COVID-19 will soon recruit healthcare staff and care home workers in the UK.

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Pfizer

NOVEMBER 2, 2022

Pfizer and BioNTech Initiate Phase 1 Study of Single Dose mRNA-Based Combination Vaccine Candidate for Influenza and COVID-19. Pfizer and BioNTech Initiate Phase 1 Study of Single Dose mRNA-Based Combination Vaccine Candidate for Influenza and COVID-19. Wed, 11/02/2022 - 15:44. Thursday, November 03, 2022 - 06:45am. Ugur Sahin, M.D.,

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Vaccine Vaccination Clinical Trials Clinical Trials 85

Scienmag

AUGUST 31, 2020

New approach enables scientists to see how immune system responds to vaccination Flu season comes around like clockwork every year, and sooner or later everyone gets infected.

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Vaccine Vaccination Scientist Allergies 75

Scienmag

OCTOBER 15, 2020

Survey also identifies socioeconomic factors associated with willingness to vaccinate A survey of U.S. adults showed that as local case counts of a hypothetical disease increased–indicating increased risk of infection–the proportion of people willing to receive a vaccine for the disease also increased.

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Vaccine Vaccination Allergies Medicine 74

Scienmag

JUNE 15, 2021

Responsibility for the safety, integrity and scientific validity of the trials fell to 12 experts of the COVID-19 Vaccine Data and Safety Monitoring Board, who now have taken the unusual step of publishing details of their review process Credit: UAB BIRMINGHAM, Ala.

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XTalks

SEPTEMBER 21, 2023

announced that the first participant has been dosed in a new Phase I trial for an innovative HIV vaccine candidate, VIR-1388. This groundbreaking endeavor has received support from the National Institute of Allergy and Infectious Diseases (NIAID). Vir Biotechnology, Inc.,

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Vaccine Vaccination Trials Clinical Trials 59

Scienmag

MARCH 15, 2021

The first vaccine has been administered in a comparative adjuvant trial of DNA prime/protein boost HIV vaccine regimens in Kericho, Kenya Credit: U.S. Military HIV Research Program SILVER SPRING, Md.

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Vaccine Vaccination Trials DNA 68

Scienmag

JUNE 21, 2021

syndrome after individuals were vaccinated against COVID-19. In two separate articles in the Annals of Neurology, clinicians in India and England report cases of a rare neurological disorder called Guillain-Barre? Both reports describe an unusual variant of Guillain-Barre? syndrome characterized by prominent facial weakness.

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Vaccination Vaccine Allergies Medicine 74

Scienmag

SEPTEMBER 1, 2020

However, the effect of the vaccine specifically against COVID-19 has not been demonstrated The BCG vaccine has a broad, stimulating effect on the immune system. This gives it an effective preventive action against various infections – possibly also against COVID-19. New studies are investigating that.

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Vaccine Vaccination Allergies Medicine 69

Scienmag

DECEMBER 14, 2020

14, 2020) – University Health Network (UHN) today gave the first COVID-19 vaccine in Canada. “UHN is proud to play a leading role in launching Canada’s COVID-19 vaccination program. Toronto (Dec. These past nine months […].

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Vaccine Vaccination Allergies Medicine 73

Scienmag

OCTOBER 27, 2020

To allow meaningful comparison between COVID-19 vaccine candidates and ensure that the most effective candidates are deployed, researchers working on different vaccines should collaborate and assess vaccine efficacy using standardised methods To allow meaningful comparison between COVID-19 vaccine candidates and ensure that the most effective candidates (..)

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Vaccine Vaccination Research Allergies 71

Pfizer

DECEMBER 8, 2022

FDA Fast Track Designation for Single-Dose mRNA-Based Vaccine Candidate Against COVID-19 and Influenza. FDA Fast Track Designation for Single-Dose mRNA-Based Vaccine Candidate Against COVID-19 and Influenza. INDICATION & AUTHORIZED USE Pfizer-BioNTech COVID-19 Vaccine, Bivalent, (Original and Omicron BA.4/BA.5) AUTHORIZED USE .

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Vaccine Vaccination Clinical Trials Clinical Trials 81

Scienmag

JUNE 27, 2021

Study points towards role of gut microbiome in vaccine effectiveness Credit: Image by Dr. Hiroshi Kiyono, CC BY 4.0 A new vaccine to protect against deadly cholera has been made by grinding up genetically modified grains of rice. The first human trial has shown no obvious side effects and a good immune response.

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Vaccine Vaccination Immune Response Trials 72

Scienmag

MARCH 24, 2021

Governments should prioritise surgical patients for COVID-19 vaccination Patients waiting for elective surgery should get COVID-19 vaccines ahead of the general population – potentially helping to avoid thousands of post-operative deaths linked to the virus, according to a new study funded by the NIHR. Between 0.6%

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