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RVAC and University of Pennsylvania to develop mRNA vaccines

Pharmaceutical Technology

RVAC Medicines has announced a research collaboration with the University of Pennsylvania (Penn) for the discovery and development of mRNA vaccines. The mRNA vaccine candidates will help reduce the chances of autoimmune responses that might lead to allergic conditions or serious autoimmune diseases.

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HIV vaccines suffer setbacks but new approaches could turn the tide

Pharmaceutical Technology

Only a few weeks into the new year, the prospect of getting a successful advanced HIV vaccine shrank after the discontinuation of yet another late-stage trial. On January 18, Janssen, a Johnson & Johnson (J&J) subsidiary, stated that its vaccine was not effective in preventing HIV infections.

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Coronavirus vaccine may have allergy warning in US, says expert

pharmaphorum

The US government’s coronavirus vaccine chief has said that Pfizer/BioNTech’s vaccine could carry a warning that it should be avoided by people who are prone to serious allergic reactions. Both recovered after appropriate treatment. Both are recovering well.”.

Allergies 103
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COVID-19 vaccines and allergies: Updated advice needs to reach a wider audience, says BMJ

BioPharma Reporter

At the end of December, the UK's Medicines and Healthcare products Regulatory Agency (MHRA) updated its advice on the Pfizer/BioNTech vaccine: saying that those with unrelated allergies could receive it. But this announcement did not receive as much coverage as the MHRAâs earlier pause on vaccination in people with allergies.

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Published Phase I Results Hint at Durability of Moderna's COVID-19 Vaccine

BioSpace

National Institutes of Allergy and Infectious Diseases (NIAID) published a letter in The New England Journal of Medicine describing the three-month immunogenicity levels in Moderna’s mRNA-1273 vaccine. Researchers with the U.S.

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2022 in review: Drug development milestones for tropical diseases

Pharmaceutical Technology

Novel therapeutics and vaccines for malaria. Novartis and the non-profit Medicines for Malaria Venture (MMV) announced plans to collaborate on a Phase III study of a novel ganaplacide/lumefantrine-SDF combination for adults and children. Apart from vaccines, other approaches for preventing malaria are also being studied.

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Doubts emerge over AZ’s ‘outdated’ US vaccine trial data

pharmaphorum

AstraZeneca has been rebuked by a US health authority after a trial monitoring board said data published from a large study of its COVID-19 vaccine may be out of date and may not give a representative view of its efficacy. AstraZeneca is preparing to file this and other trial data with the FDA asking for an emergency approval of the vaccine.