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It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The NIAID-supported COVID-19 Prevention Network (CoVPN) participated in the trial. JPEO-CBRND.
It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The NIAID-supported COVID-19 Prevention Network (CoVPN) participated in the trial. JPEO-CBRND.
Cellular (T cell) response were observed to multiple regions of the spike protein including the RBD region. .
The 1.0 mg and 2.0 mg dose group both demonstrated seroconversion in 95% of the subjects, respectively, with 78% demonstrating neutralizing antibodies in the 1.0 mg dose group.
It will be funded by the U.S.
These companies include Moderna, a US biotech company which has formed a partnership with the National Institute of Allergy and Infectious Diseases (NIAID), Oxford University who has partnered with AstraZeneca, and Johnson & Johnson, Merck and Pfizer. University of Oxford and AstraZeneca COVID-19 Vaccine.
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