pharmaphorum

DECEMBER 23, 2021

Children in England with peanut allergies could be among the first in Europe to get access to Aimmune’s oral immunotherapy Palforzia, after the drugmaker agreed a supply deal with NHS England. billion last year, is also developing immunotherapies for other indications including egg and multi-tree nut allergies.

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Allergies Drugs Clinical Trials Clinical Trials 124

Pharmaceutical Technology

OCTOBER 12, 2023

The Phase III trial of ALK’s allergy immunotherapy tablet met its primary endpoint for the treatment of tree-pollen-induced allergics.

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Trials Allergies 147

STAT News

JANUARY 18, 2023

The National Institute of Allergy and Infectious Diseases reported Wednesday that a Phase 3 clinical trial of a vaccine was stopped because the vaccine was ineffective at preventing HIV infection. Yet another experimental HIV vaccine has failed. The vaccine was being developed by Janssen, the vaccine division of Johnson & Johnson.

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Clinical Trials Clinical Trials Vaccine Vaccination 145

Pharmaceutical Technology

JULY 26, 2023

Intrommune Therapeutics has completed the last patient last visit for its desensitisation candidate INT301.

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Allergies Trials 130

Delveinsight

AUGUST 2, 2021

Peanut allergy (PA) is one of the most common food allergies that affect children in Western nations. Historically, the gold standard of the treatment for Peanut allergy constituted a strategic plan for peanut avoidance coupled with an adrenaline auto-injector (AAI) in case of contingencies.

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Allergies Marketing Development Trials 97

ACRP blog

OCTOBER 10, 2024

It’s even being used to review investigator invoices and automate financial reconciliations—a monthly headache every contract research organization, sponsor, and clinical trials operator will be more than happy to resign to machines. A Blueprint for Adoption in Clinical Trials That’s where large integrated site organizations come in.

Clinical Trials 69

Clinical Trials Clinical Trials Trials Life Science 69

pharmaphorum

DECEMBER 10, 2020

Moncef Slaoui, co-head of the US government’s Operation Warp Speed COVID-19 vaccine programme, made the comments after the UK drugs regulator advised those with severe allergies to avoid the vaccine. The post Coronavirus vaccine may have allergy warning in US, says expert appeared first on.

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Allergies Vaccination Vaccine Regulation 103

Scienmag

JANUARY 20, 2022

A clinical trial funded by the National Institutes of Health has found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 years safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth. The immunotherapy consisted of a daily oral dose of peanut flour for 2.5

Allergies 89

Allergies Trial Funding Clinical Trials Clinical Trials 89

XTalks

MARCH 10, 2025

Originally approved by the FDA over two decades ago for the treatment of moderate to severe persistent asthma, Xolair recently also gained approval for managing food allergies. In a global Phase III clinical trial, 619 adult patients were enrolled and received either 150 mg or 300 mg of omalizumab-igec every four weeks.

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Allergies FDA Approval Antibody Trials 66

Pharma Mirror

DECEMBER 1, 2021

Rockville, Emmes today announced that it conducted the data and statistical analysis for the third iteration of the Adaptive COVID-19 Treatment Trial (ACTT-3), using its proprietary Advantage eClinical system. The post Emmes Announces Completion of Third ACTT Clinical Trial for COVID-19 appeared first on Pharma Mirror Magazine.

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Clinical Trials Clinical Trials Trials Allergies 130

Rethinking Clinical Trials

NOVEMBER 29, 2022

The NIH Pragmatic Trials Collaboratory is excited to welcome the INSPIRE Demonstration Project to its portfolio of innovative, large-scale pragmatic clinical trials embedded in healthcare systems. Although fewer than 5% of such patients have an antibiotic-resistant infection, more than half receive extended-spectrum antibiotics.

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Trials Clinical Trials Clinical Trials Allergies 130

Pharmaceutical Technology

SEPTEMBER 16, 2022

The latest conditional recommendation is based on the final data from the SOLIDARITY clinical trial, which was sponsored by the WHO. These results are in line with those obtained from the placebo-controlled, double-blind ACTT-1 trial of the National Institute of Allergy and Infectious Diseases.

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Allergies RNA Clinical Trials Clinical Trials 277

Medical Xpress

FEBRUARY 28, 2023

A four-year clinical trial led by Edwin Kim, MD, at the UNC School of Medicine, has found that an increased dosage of a unique type of peanut allergy immunotherapy continues to show promise for children.

Allergies 75

Allergies Clinical Trials Clinical Trials Medicine 75

Deltaclinical

JANUARY 13, 2023

Home visits for clinical trials are becoming increasingly popular, as they offer a number of distinct benefits for both the patient and the provider. In this blog post, we’ll explore the top ten benefits of clinical trial home visits to help you make an informed decision about whether or not this type of service is right for your study.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Allergies 130

Deltaclinical

JANUARY 13, 2023

Home visits for clinical trials are becoming increasingly popular, as they offer a number of distinct benefits for both the patient and the provider. In this blog post, we’ll explore the top ten benefits of clinical trial home visits to help you make an informed decision about whether or not this type of service is right for your study.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Allergies 130

Deltaclinical

JANUARY 13, 2023

Home visits for clinical trials are becoming increasingly popular, as they offer a number of distinct benefits for both the patient and the provider. In this blog post, we’ll explore the top ten benefits of clinical trial home visits to help you make an informed decision about whether or not this type of service is right for your study.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Allergies 130

Deltaclinical

JANUARY 13, 2023

Home visits for clinical trials are becoming increasingly popular, as they offer a number of distinct benefits for both the patient and the provider. In this blog post, we’ll explore the top ten benefits of clinical trial home visits to help you make an informed decision about whether or not this type of service is right for your study.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Allergies 130

Pharmaceutical Technology

FEBRUARY 3, 2023

Only a few weeks into the new year, the prospect of getting a successful advanced HIV vaccine shrank after the discontinuation of yet another late-stage trial. This marks the second time one of Janssen’s HIV vaccines failed after another showed disappointing results in the Phase IIb Imbokodo trial in August 2021.

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Vaccine Vaccination Antibody Trials 293

Antidote

SEPTEMBER 1, 2023

As part of our efforts to better understand patients and their motivations to participate in clinical trials, Antidote and SCORR Marketing partnered on a survey to gain a deeper understanding of how patients think about the medical research process.

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Clinical Trials Clinical Trials Trials Allergies 95

Scienmag

NOVEMBER 18, 2021

Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can […].

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Clinical Trials Clinical Trials Trial Funding Trials 86

Pharmaceutical Technology

JANUARY 8, 2023

There are at least six different biologics being studied in Phase III trials in COPD clinical programmes around the world. Results from a Phase III trial with Sanofi and Regeneron Pharmaceuticals’ IL-4/IL-13 monoclonal antibody (mAb) Dupixent (dupilumab) are expected by mid-2023, followed by others. Ongoing efforts.

Antibody 298

Antibody Trials Clinical Trials Clinical Trials 298

Velocity Clinical Research

OCTOBER 21, 2024

For a clinical trials organization to achieve this level of scale is notable. The clinical trials sector in the US is typically made up of small independent businesses that collectively play an important role in trialing new protocols and aiding drug development. Inclusivity These activities don’t just benefit trial sites.

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Clinical Trials Clinical Trials Trials Clinical Research 105

Scienmag

APRIL 21, 2021

Credit: NIAID A Phase 2/3 trial to evaluate a new fully-human polyclonal antibody therapeutic targeted to SARS-CoV-2, called SAB-185, has begun enrolling non-hospitalized people with mild or moderate cases of COVID-19.

Antibody 81

Antibody Clinical Trials Clinical Trials Trials 81

pharmaphorum

OCTOBER 27, 2020

Eli Lilly says no more patients will be treated with its COVID-19 therapy bamlanivimab in a trial run by the US National Institute of Allergy and Infectious Diseases (NIAID), as results to date suggest it is unlikely to be effective. The post NIAID drops Lilly antibody from ACTIV-3 COVID-19 trial appeared first on.

Antibody 105

Antibody Trials Allergies Nurses 105

NY Times

DECEMBER 18, 2020

Four people so far have had allergic reactions after getting the Pfizer-BioNTech vaccine. Experts say that shouldn’t deter most people from getting a jab.

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Allergies Vaccine Vaccination Clinical Trials 94

Medical Xpress

JANUARY 17, 2023

A promising approach to control Staphylococcus aureus bacterial colonization in people—using a probiotic instead of antibiotics—was safe and highly effective in a Phase 2 clinical trial. aureus colonization in trial participants without harming the gut microbiota, which includes bacteria that can benefit people.

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Trials Allergies Bacteria Clinical Trials 80

pharmaphorum

FEBRUARY 18, 2022

Sanofi and Regeneron have reported disappointing results in a trial of Dupixent in people with chronic spontaneous urticaria (CSU) who don’t respond to the only approved biologic treatment, Novartis/Roche’s Xolair. . The post Dupixent falls short in phase 3 chronic spontaneous urticaria trial appeared first on.

Trials 105

Trials Sales Allergies Drugs 105

JAMA Internal Medicine

JULY 16, 2023

This randomized clinical trial aims to determine whether a direct oral penicillin challenge is noninferior to the standard of care of penicillin skin testing followed by an oral challenge in patients with a low-risk penicillin allergy.

Allergies 56

Allergies Clinical Trials Clinical Trials Trials 56

World of DTC Marketing

OCTOBER 6, 2021

In the first 29 days of the trial, no deaths were reported among the 385 patients who received the drug, while eight of the people who received a placebo died, according to the statement put out by Merck and Ridgeback Biotherapeutics, the two companies that are jointly launching it. million for NIH-funded clinical trials.

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Clinical Trials Clinical Trials Allergies Trials 198

pharmaphorum

MARCH 23, 2021

AstraZeneca has been rebuked by a US health authority after a trial monitoring board said data published from a large study of its COVID-19 vaccine may be out of date and may not give a representative view of its efficacy. AstraZeneca is preparing to file this and other trial data with the FDA asking for an emergency approval of the vaccine.

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Vaccine Vaccination Trials Allergies 98

Rethinking Clinical Trials

JANUARY 24, 2023

The trial is comparing routine care under hospital-based antibiotic stewardship programs with an enhanced program that adds a predictive algorithm to reduce unnecessary prescribing of extended-spectrum antibiotics.

Allergies 130

Allergies Clinical Trials Clinical Trials Trials 130

pharmaphorum

SEPTEMBER 16, 2020

Adding Eli Lilly’s rheumatoid arthritis drug Olumiant (baricitinib) and Gilead Sciences’ remdesivir reduces recovery time in COVID-19 patients compared to remdesivir alone, says a new trial. The post Trial backs Lilly’s Olumiant plus remdesivir as combo COVID-19 therapy appeared first on.

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Trials Trial Funding Allergies Drugs 111

Clinical Trial Podcast

SEPTEMBER 26, 2022

To answer these two questions, regulatory authorities around the world require medical product manufacturers to conduct Phase I, also known as early phase clinical trials. The post Complexity in Early Phase Clinical Trials with Dr. Oren Cohen? The post Complexity in Early Phase Clinical Trials with Dr. Oren Cohen?

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Clinical Trials Clinical Trials Trials Clinical Research 98

Trialfacts

JANUARY 23, 2024

More Study Details About the Study A peanut allergy can be severe and life-threatening if not treated promptly. Peanut allergies are one of the most common food allergies in children in the USA, with more than 2% of children being affected. Participants will receive a new potential treatment for their peanut allergy at no cost.

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Allergies Research Doctor Doctors 52

STAT News

SEPTEMBER 12, 2022

National Institutes of Health is launching a Phase 3 clinical trial to determine the efficacy of tecovirimat — the smallpox antiviral better known as TPOXX — for use in treating monkeypox, as current data on its effectiveness against the virus is limited , The Hill writes. The TPOXX was approved by the U.S.

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FDA Approval Trials Clinical Trials Clinical Trials 98

Medical Xpress

MARCH 6, 2023

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. A non-temperature stable form of the candidate previously had been tested in several clinical trials.

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Immune Response Vaccine Vaccination Trials 75

Druggist

APRIL 20, 2021

Today I will explore a different use of montelukast and answer the main question: can you use montelukast for allergies? Can you use montelukast for allergies? Can you use montelukast for allergies? Use of montelukast for allergies: what is the evidence? . Summary: What is montelukast. Licensed use of montelukast.

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Allergies Licensing Licensing Drugs 52