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Genentech’s New Ocular Implant Drug Delivery System for Macular Degeneration Could Be a Game Changer

XTalks

Genentech’s ocular implant drug delivery system for treatment of macular degeneration has received approval from the US Food and Drug Administration (FDA). Susvimo delivers ranibizumab via a port delivery system into a surgically placed implant in the eye, allowing for continuous delivery of the drug.

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Nemolizumab Approved for Adults with Prurigo Nodularis

XTalks

The US Food and Drug Administration (FDA) has approved Galderma’s monoclonal antibody Nemluvio (nemolizumab) for the treatment of adult patients with the chronic skin condition prurigo nodularis. Monoclonal antibody therapy has been found to have fewer side effects when compared to immunosuppressant drugs.

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Exosomes: A Deeper Look into Service Providers Market

Roots Analysis

Broad Clinical Trial Landscape. Till date, over 180 clinical studies which primarily include completed, ongoing and planned trials evaluating various clinical research activity related to exosomes and involving nearly 2,392 patients enrolled across different centers / hospitals, have been initiated worldwide.

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Liposomes Development: Service Providers Landscape

Roots Analysis

Broad Clinical Trial Landscape Till date, close to 800 clinical studies evaluating various liposome-based therapeutics have been initiated worldwide. Further, the most targeted disease area within oncological disorders is ovarian cancer, with 226 clinical trials registered in the given time period.

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Top Emerging Therapies To Watch Out for in the Retinal Vein Occlusion Market

Delveinsight

Therapies such as dexamethasone drug delivery system and vascular endothelial growth factor inhibitors have already pierced deeper into the market. Brolucizumab is a humanized single-chain antibody fragment (scFv). The company has plans to initiate new trials for the product however not until the second half of 2021.

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Next Generation Complement Therapeutics: Potential Life-Changing Therapies for Multiple Rare Disorders

Roots Analysis

Since the approval of Soliris® in 2007, an anti-C5 antibody, the field of complement drug discovery has gained significant attention. Broad Clinical Trial Landscape. Currently, nine complement therapeutics are commercially available, while around 190 molecules are under development for various disease indications.

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Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

Filipe Rodrigues, MD/MSc, Medical Director at Medpace spoke about the modern-day applications of direct CNS administration, including intrathecal, intraparenchymal and ICV delivery. Such therapies may involve small interfering RNA (siRNA) or oligonucleotides in viral transfection platforms, large molecules and antibodies. Figure 3 ).

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