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Antibodies, Immunity, and COVID-19

JAMA Internal Medicine

Widespread availability of commercial assays that detect anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies has enabled researchers to examine naturally acquired immunity to coronavirus disease 2019 (COVID-19) at the population level.

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No drugs for prions: could new approaches alleviate therapeutic scarcity?

Pharmaceutical Technology

This is also why academic research is dominant here, as companies are hesitant to take this on, adds Holger Wille, PhD, associate professor at the Centre for Prions and Protein Folding Diseases at the University of Alberta. Adding to this, the infectivity of prion diseases also makes research challenging, says Wille.

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Maternal Antibodies: How Allergies Can be Passed from Mothers to Children

XTalks

It has long been known that mothers greatly influence the development of the growing fetus by not only providing nutrients through the placenta, but also a growing list of biological elements including beneficial antibodies, gut bacteria and now, allergies. This is in contrast to adult mice, which need two exposures.

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Leading freeze-drying systems suppliers for the pharmaceutical industry

Pharmaceutical Technology

Pharmaceutical and biotechnology industries widely use freeze-drying systems to protect vaccines, antibodies, antibiotics such as penicillin, blood plasma, proteins, enzymes, hormones, viruses, and bacteria from heat and minimise their biological activity. The process eliminates the disadvantages of conventional drying methods or freezing.

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Merck wins regulatory approval for combination therapy to treat la/mUC

Pharmaceutical Technology

The combination therapy can be used to treat la/mUC patients who do not qualify for cisplatin-containing chemotherapy. Merck stated that the regulatory approval represents the first of its kind received by an anti-PD-1 therapy in combination with an antibody-drug conjugate for use in targeted patients in the US.

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Research Roundup: Different Antibody Responses to COVID-19 and More

The Pharma Data

Antibodies Respond Differently to Severe Versus Mild COVID-19. Researchers at Stanford Medicine found that COVID-19 antibodies preferentially target different parts of the SARS-CoV-2 virus in mild COVID-19 cases than they do in severe cases. In milder cases, the antibodies seem to do a better job of binding to the spike protein.

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Johns Hopkins-led study finds convalescent plasma can be effective early Covid-19 therapy

Scienmag

The New England Journal of Medicine (NEJM) today published final results of a nationwide multicenter study led by researchers at Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health that show plasma from patients who have recovered from COVID-19 and whose blood contains antibodies against SARS-CoV-2, the causative virus, is (..)