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Amgen pays Kyowa $400m upfront for OX40 eczema drug

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The deal gives Amgen rights to the KHK4083 antibody in all countries except Kyowa’s home market of Japan, and is back-loaded with potential milestone payments worth another $850 million plus royalties on sales. Kyowa will co-promote the drug in the US if approved, with opt-in rights in some other countries as well.

Drugs 52
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Amgen Reports Second Quarter 2021 Financial Results

The Pharma Data

Product sales increased 3% globally, driven by double digit volume growth across a number of our products including Prolia ® (denosumab), Repatha ® (evolocumab) and our biosimilar products MVASI ® (bevacizumab-awwb) and KANJINTI ® (trastuzumab-anns). Product Sales Performance. Key results include: Total revenues increased 5% to $6.5

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Avillion/Merck psoriasis nanobody hits the mark in phase 2

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Merck licensed sonelokimab (M1095) from Ablynx in 2013, and four years later formed a partnership with Avillion to carry out phase 2 and 3 testing of the drug. The drug is a nanobody, a molecule around one-tenth the size of a regular antibody derived from camelid species such as the llama. billion in sales last year.

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Dermavant claims its first approval as FDA clears psoriasis drug

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But while the company is adamant sales will pick up quickly, analysts have predicted a more challenging start for the new product. Tapinarof was GSK’s lead drug in immuno-inflammation R&D back in 2018 before it was licensed by Dermavant in a £250 million ($330 million) deal. Image by Anastasia Gepp from Pixabay.

Drugs 52
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MoonLake launches, licensing in Merck KGaA’s Cosentyx challenger sonelokimab

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There’s a new biotech on the scene after MoonLake Immunotherapeutics launched on a mission to develop sonelokimab, a potential inflammatory diseases drug in-licensed from Germany’s Merck KGaA. MoonLake has swiftly in-licensed the drug discovered by Sanofi’s Ablynx unit, with plans to develop the drug targeting IL-17A and F.

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Saphnelo (anifrolumab) approved in the US for moderate to severe systemic lupus erythematosus

The Pharma Data

Saphnelo is a first-in-class type I interferon receptor antibody and the only new medicine in over a decade for patients with systemic lupus erythematosus . Financial considerations AstraZeneca acquired global rights to Saphnelo through an exclusive license and collaboration agreement with Medarex, Inc.

Trials 52
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Almirall demonstrates resilient performance year to date despite COVID-19 impacts

The Pharma Data

9, 2020 /PRNewswire/ — Solid 9M business performance despite COVID-19 and generic Aczone challenges: Net Sales €613.8 Ilumetri ® sales grew +125% year-on-year and Seysara ® showed Net Sales performance improvement quarter-on-quarter following clinically relevant FDA label improvement. BARCELONA, Spain , Nov.