Pharmaceutical Technology

JANUARY 19, 2023

AOC 1020 has been designed for the treatment of the underlying cause of FSHD, which is caused by the abnormal expression of a gene known as double homeobox 4 or DUX4. Avidity Biosciences’ AOC 1020 is intended to reduce the DUX4 mRNA and DUX4 protein expression in muscles in these patients.

Gene Expression 246

Gene Expression Gene Protein RNA 246

The Pharma Data

SEPTEMBER 2, 2021

In mice, an antibody directed against this factor was able to slow the growth of metastatic tumors.Blood vessels produce growth factor that promotes metastases. ” With a particular focus on the lung, the researchers performed global gene expression analyses of the metastatic niche.

Gene Expression 52

Gene Expression Scientist Antibody Research 52

Pharmaceutical Technology

JUNE 4, 2023

Adeno-associated virus vectors, alcohol dehydrogenase compositions, and antibody serum stabilisers are some of the accelerating innovation areas, where adoption has been steadily increasing. Among maturing innovation areas are anti-influenza antibody compositions and anti-interleukin-1, which are now well established in the industry.

Genetics 130

Genetics Gene Expression DNA Antibody 130

Roots Analysis

OCTOBER 22, 2023

Coding RNAs include messenger RNA (mRNA) and short interfering RNA (siRNA), which encode proteins and silence gene expression, respectively. ASOs are short single-stranded nucleotides that bind to specific messenger RNAs and prevent the production of a particular protein.

RNA 40

RNA Protein Genetics Gene Expression 40

XTalks

MARCH 22, 2021

The biotech acquisition will also see Takeda getting Maverick’s TAK-280 (MVC-280), an immunotherapy designed to treat patients with B7H3-expressing solid tumors which is expected to enter the clinic later this year. The biotech acquisition deal includes Five Prime’s prime asset bemarituzumab, which is a first-in-class anti-FGFR2b antibody.

Life Science 110

Life Science Development Marketing Gene Expression 110

The Pharma Data

AUGUST 3, 2021

HDACs catalyze the removal of acetyl groups from acetylated lysine residues in histones, resulting in the modulation of gene expression. HDACs also deacetylate non-histone proteins, such as transcription factors. Reactivation of hepatitis B virus infection was reported in 1% of patients in clinical trials.

In-Vitro 52

In-Vitro Nurses Gene Expression Medicine 52

Delveinsight

JULY 30, 2020

Roche bets USD 120 Million on UCB’s anti-tau Alzheimer’s antibody. The Swiss pharma, Roche, is handing over USD 120 million upfront for the right of UCB’s anti-tau antibody development. Omega’s platform is designed to adjust gene expression to healthy levels rather than switching genes on and off.

Genome 52

Genome Genomics Antibody Gene 52