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Could an Antibody Drug Help You Shed Pounds?

The Pharma Data

2, 2020 — An experimental antibody drug that targets one of the body’s key metabolism regulators may help obese people lose weight — at least briefly. It would take much more research to prove the antibody is safe and effective, Ryan said. MONDAY, Nov. She was not involved in the study.

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Biocon buys Viatris biosimilars for $3.3bn, eyes IPO

pharmaphorum

Biocon’s partnership with Mylan – which merged with Pfizer’s Upjohn to form Viatris in 2020 – dates back more than a decade and has generated a number of biosimilars including insulin analogues, antibodies and recombinant proteins.

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Receptor Occupancy Assays by Flow Cytometry: Benefits for Clinical Trials

XTalks

Generally, antibody-based therapeutics are one of the main types of drugs that are assessed using receptor occupancy assays as they bind to specific cell surface receptors through which they impact downstream intracellular signalling pathways. The antibodies are conjugated to fluorochromes for them to be detected.

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FDA rejects BioMarin’s Valoctocogene Roxaparvovec; J&J inks $6.5B deal; Alzheon bags $47M; Research updates on diabetes

Delveinsight

Generating insulin-producing pancreatic beta cells from stem cells to substitute those damaged by the immune system is a promising approach for diabetes treatment. The takeover will proffer J&J control of an anti-FcRn antibody, which completed a phase 2 trial in myasthenia gravis earlier this year.

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Surrogate Endpoints: How to Choose the Best One for Your Rare Disease Trial

XTalks

Acromegaly Surrogate Endpoint: Serum growth hormone and serum insulin-like growth factor 1 (IGF-1) are acceptable surrogate endpoints for acromegaly clinical trials involving somatostatin analogs such as octreotide, lanreotide and pasireotide. Dietary changes, including restriction of salt and animal protein, are also recommended.

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Advances in the Battle Against Autoimmune Disease

The Pharma Data

On top of this, another 8 million carry auto-antibodies, blood molecules that indicate a person’s chance of developing an autoimmune disease. Scientists will be testing a drug class targeting the C-reactive protein (CRP) marker of acute inflammation in the body. Monoclonal Antibodies.

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Top 10 Medical Device Companies in 2023 by Revenue Statistics and Trends

XTalks

Internationally, Medtronic expanded its MiniMed 780G insulin pump and Guardian 4 sensor. In addition, the company received FDA approval for the Pathway anti-HER2 (4B5) Antibody assay , intended to detect HER2 protein in patients with breast cancer. It also plans to launch these products in the US.