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A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence

Scienmag

of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. . – Lei Zhang, Ph.D., and Michael Niederweis, Ph.D.,

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis. “Our study took a novel approach to look directly into the bacterium’s behavior in the human host.”

RNA 40
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Anti-tumor agent from the intestine

The Pharma Data

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. In doing so, they induce epigenetic changes.

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Top 30 Pharma and Biotech Companies in 2023: Statistics and Trends

XTalks

Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A. 2) Botox Therapeutic/Cosmetic Botox, or botulinum neurotoxin, is a neurotoxic protein produced by the Clostridium botulinum bacteria. But all three drugs have new competitors. Both are anti-CD20 agents. billion in 2022.

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2020 Year in Review: COVID-19, CRISPR and Immunotherapies Define the Year for the Life Sciences

XTalks

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. CRISPR Gene Editing Inventors Win Nobel Prize.

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World AMR Awareness Week 2024: New Antimicrobial Resistance Research

XTalks

This theme addresses antimicrobial resistance (AMR), a critical issue where bacteria, viruses, fungi and parasites develop resistance to treatments, making infections harder — or sometimes impossible — to treat effectively. uUTIs are being increasingly caused by drug-resistant bacteria, leading to higher treatment failure rates.

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