Roots Analysis

FEBRUARY 27, 2024

How many of the ADCs in development have pyrrolobenzodiazepine (PBD) as warhead: Pyrrolobenzodiazepines are a class of compounds that kill cells by binding their DNA and interfering with replication. In nature, they are made by a group of bacteria known as actinomycetes.

Antibody 52

Antibody Licensing Licensing Contract Manufacturing 52

XTalks

FEBRUARY 11, 2021

The increased production aims will be achieved through both improved manufacturing efficiency and increasing build capacity. The drugmaker is targeting various steps in the manufacturing process, beginning right at the DNA stage, which is required as the template from which the mRNA for the SARS-CoV-2 spike protein in the vaccine is made.

Manufacturing 52

Manufacturing Vaccination Vaccine DNA 52

Roots Analysis

JANUARY 14, 2024

Different types of expression system for the production of biologics have been mentioned in the following sections: Insect Expression Systems: Baculovirus is a double stranded DNA (dsDNA) lytic virus that can be effectively amplified in insect cells belonging to the Lepidoptera family.

Contract Manufacturing 40

Contract Manufacturing Protein Manufacturing Production 40