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Gene Therapy and Pharmacokinetics

Camargo

When developing a clinical development program for these increasingly popular therapies, it is important that sponsors use modeling and pharmacokinetic (PK) analysis to evaluate parameters that can be measured while dosing with gene therapy drugs, to characterize exposure-response data and inform rational dosing. Gene Therapy Definition.

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Engineering an “invisible cloak” for bacteria to deliver drugs to tumors

The Pharma Data

Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Using Bacteria For Therapy. ” The Ideal Bacteria.

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Likmez: First FDA-Approved Liquid Option of the Antibiotic Metronidazole

XTalks

Kesin Pharma has obtained approval from the US Food and Drug Administration (FDA) for its oral suspension antibiotic drug Likmez (metronidazole), designed for patients with dysphagia and difficulty swallowing. Likmez offers a safer alternative by mitigating the associated risks linked to off-label drug compounding.

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CRISPR pioneers Doudna and Charpentier claim Nobel chemistry prize

pharmaphorum

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. million) Nobel Prize award.

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Fight Against the Antibiotic Resistance in the Uncomplicated Urinary Tract Infections Market

Delveinsight

Some of the most commonly prescribed antibiotics in the Uncomplicated Urinary Tract Infection therapy market include the combination drug trimethoprim and sulfamethoxazole, trimethoprim, ?-lactams, coli bacteria called FimH. coli bacteria called FimH. The drug is in the development stage of Phase I clinical trial.

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The future of genomic medicine: can it fulfil its promises?

pharmaphorum

If you are developing a drug, for example, for infantile epilepsy, then you need to know if your drug target is expressed in the brain and also during early development. Likewise, some patients may have a different version of a gene with respect to people on whom a drug has been tested, which means that drug might not work.”.

Genomics 119
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Nobel winner Charpentier’s CRISPR Therapeutics gets $900m in reworked Vertex deal

pharmaphorum

Founded by Nobel prize winner Emmanuelle Charpentier, CRISPR Therapeutics has been at the forefront of gene editing technology and has refined its technology to the point where it can be used to accurately edit someone’s DNA to correct genetic conditions.