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MBL team discovers new DNA modification system in animals, captured from bacteria more than 60 MYA

Scienmag

— Your DNA holds the blueprint to build your body, but it’s a living document: Adjustments to the design can be made by epigenetic marks. — Your DNA holds the blueprint to build your body, but it’s a living document: Adjustments to the […]. WOODS HOLE, Mass. Shribak and I. Yushenova WOODS HOLE, Mass.

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Engineering an “invisible cloak” for bacteria to deliver drugs to tumors

The Pharma Data

Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Sheng Professor of Biomedical Engineering. Using Bacteria For Therapy.

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Regulating the ribosomal RNA production line

Scienmag

coli enzyme synthesizing ribosomal RNA that shift it between turbo- and slow-modes depending on the bacteria’s growth rate Credit: Murakami Laboratory, Penn State The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the […].

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CRISPR Therapeutics begins natural killer cell cancer tie-up with Nkarta

pharmaphorum

Founded by Nobel prize winner Emmanuelle Charpentier, CRISPR Therapeutics has been at the forefront of the gene editing technology and has refined it to the point where it can be used to accurately edit DNA to correct genetic conditions or modify cells to fight disease.

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Pfizer to Slash COVID-19 Vaccine Manufacturing Time by Almost 50 Percent

XTalks

The company is on track to fulfill the 200 million-dose order put in by the US government by May, but hopes to have more available as engineers improve systems on the go. As soon as vaccine vials began coming off the production line, engineers started analyzing how production could be made faster and better. coli bacteria.

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Could Fluoride be the Solution to Antibiotic Resistance? A New Study Weighs In

The Pharma Data

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. “Essentially, what Justin did was to create a series of DNA instructions you can give to cells that will enable them to survive when fluoride is around,” said O’Malley.

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Gene Switch: A Novel Platform for Switching Genes On and Off

Roots Analysis

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Gene switches can be regulatory proteins or specific DNA sequences that act to either switch on or off the expression of a gene.

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