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Scientists have developed a vaccine against a notorious drug-resistant superbug, targeting molecules on its surface that are also found on other bacteria and fungi.
The New York biotech will invest in and develop up to three drugs with Gensaic, an emerging startup aiming to use the viruses that infect bacteria to deliver genetic medicines.
As antimicrobial resistance (AMR) poses a growing threat to global public health, challenging the effectiveness of antibiotics and other antimicrobial drugs, medical experts suggest whole genome sequencing as a viable option to identify and characterize the bacteria, viruses, fungi or parasites, along with their transmission pattern.
The Technical University of Denmark (DTU) has announced that an international scientific team has developed a CRISPR-based drug candidate that targets E coli directly and leaves the microbiome intact. Blood cancer patients with E coli infection are at risk of bacteria infecting the bloodstream.
A pill made of gut bacteria wasn't effective at treating ulcerative colitis in a closely watched study that was viewed as a proof point for the emerging field.
Despite the growing threat of drug-resistant bacteria, few new antibiotics are reaching the market because of hurdles that biotech executives and experts say stand in the way.
For a team of Canadian and French researchers, dark clouds on the horizon are potentially ominous not because they signal an approaching storm—but because they were found in a recent study to carry drug-resistant bacteria over long distances.
Bayer has agreed to make a payment of $40m for settling claims over the alleged violations of the False Claims Act linked to three drugs, Trasylol, Avelox and Baycol, the US Department of Justice said in a press statement. Simpson also alleged that the company sold these drugs for off-label usages that were not acceptable and essential.
Naturally occurring gut bacteria can clean up chemo toxins in the body, study finds Credit: Northwestern University In the human gut, good bacteria make great neighbors.
Golden staph are ubiquitous bacteria, living harmlessly on the skin or inside the nose of nearly one in three people worldwide. Some strains are also drug-resistant ‘superbugs,’ armed with features […] Yet they are duplicitous, too.
health officials are advising people to stop using over-the-counter eye drops that have been linked to an outbreak of drug-resistant infections. NEW YORK — U.S. The Centers for Disease Control and Prevention on Wednesday night sent a health alert to physicians, saying the outbreak includes at least 55 people in 12 states.
Pneumonia is a lung infection that can be caused by viruses, bacteria or fungi and can result in millions of hospitalizations and deaths annually. Thus, to address drug-resistant infections, pharma and biotech companies are developing novel treatments such as bacteriophage therapies, immunomodulators and monoclonal antibodies.
Credit: Purdue University photo/Mark Simons Your gut bacteria could say a lot about you, such as why you’re diabetic or how you respond to certain drugs. But scientists can see only so much of the gastrointestinal tract to study the role of gut bacteria in your health. What comes out of you is just a […].
Credit: RIKEN A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. In doing so, they were able to identify the mechanisms and constraints underlying evolved drug resistance.
Drugs tainted with impurities ranging from bacteria and particulates to likely cancer agents have triggered multiple FDA recalls in recent years. Drugs tainted with impurities ranging from bacteria and particulates to likely cancer agents have triggered multiple FDA recalls in recent years.
The extensively drug-resistant strain is relatively uncommon overall, but it's being seen in more cases among adults. Shigella causes shigellosis, an inflammatory diarrhea. Image credit: Stephanie Rossow/Science Source)
The Food and Drug Administration approved the first therapy using bacteria from stool samples to treat a bowel disorder on Wednesday, paving the way for several similar treatments in development. The drug, called Rebyota, is given as a one-dose treatment for clostridium difficile infection s, commonly known as C.
Cronobacter sakazakii , the bacteria linked to recent baby formula shortages and the Abbott infant formula recall, could soon join the federal disease watchlist. Also known as Enterobacter sakazakii , Cronobacter sakazakii is a bacteria that can cause severe infections, particularly in infants, and is associated with high mortality rates.
Traditional folk remedies in rural Italy inspired the research Credit: Quave Lab Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria. Frontiers in Pharmacology published the finding, led by scientists at Emory University.
Credit: The Medina Group/Penn State Drug-resistant bacteria could lead to more deaths than cancer by 2050, according to a report commissioned by the United Kingdom in 2014 and jointly supported by the U.K. government and the Wellcome Trust.
Credit: UM photo MISSOULA – University of Montana researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis. The research was published Feb. 23 in the journal Cell Reports.
Process paves a road to safe, ethical, and fast drug manufacturing Credit: Rensselaer Polytechnic Institute TROY, N.Y. — Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.
Food and Drug Administration) Reckitt says despite contamination fears, the recalled formula tested negative for Cronobacter, which can cause rare but deadly infections in infants. Here's how to identify and prevent them. Image credit: U.S.
The results, published today in Nature Communications, provide the first direct evidence of AMR bacteria migrating from a patient's gut microbiome to the lungs, increasing the risk of deadly infections.
Research suggests that certain bacteria, particularly those associated with Demodex mites (tiny mites that naturally live on human skin) like Bacillus oleronius , could contribute to rosacea in some individuals. Other studies suggest that Helicobacter pylori bacteria infections may also cause rosacea.
Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth. The research answers a long-standing biological question and could have implications for the timing of drug delivery, biotechnology, and […].
A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick. A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from […].
Infections from drug-resistant bacteria have caused death and illness in 68 patients across the U.S., the CDC says. The strain has been linked to recalled eyedrops like EzriCare Artificial Tears. Image credit: Janice Haney Carr/AP)
Belfast startup AMPLY has raised £900,000 to develop a range of new products that hopes to tackle multi-drug resistent pathogens using its artificial intelligence (AI) drug discovery platform. Antimicrobial resistance is when bacteria and viruses become resistant to medication, making previous treatments ineffective. “The
Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.
In the fight against multidrug-resistant bacteria, scientists in Sweden have developed a new kind of antibiotic-free protection for wounds that kills drug-resistant bacteria and induces the body’s own immune responses to fight infections.
Following in the footsteps of Sanofi and Moderna, Eli Lilly on Tuesday inked a collaboration agreement with OpenAI to develop novel antimicrobial agents against drug-resistant pathogens.
Washington, DC – June 20, 2021 – Researchers from the Miami University in Ohio have optimized a new technique that will allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria.
Credit: University of Groningen Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson’s disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility.
Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests a new study presented Monday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga.
Credit: Shutterstock Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics. The findings offer a potential new drug target in the search for effective new antibiotics as we face the growing threat of antimicrobial resistance (AMR) and infections caused by bacterial pathogens.
Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Using Bacteria For Therapy. ” The Ideal Bacteria.
The research advances understanding of bacteria vulnerability and opens the door to new methods of fighting drug-resistant bacteria Credit: Russell Cothren FAYETTEVILLE, Ark.
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