Scienmag

OCTOBER 19, 2020

Credit: University of Groningen Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson’s disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility.

Bacteria 56

Bacteria Drugs Scientist Medicine 56

Scienmag

DECEMBER 9, 2020

A new genetic approach can accelerate the study of phage-microbe interactions with implications for health, agriculture, and climate Credit: Wikimedia Commons Scientists are continually searching for new and improved ways to deal with bacteria, be it to eliminate disease-causing strains or to modify potentially beneficial strains.

Bacteria 52

Bacteria Genetic Engineering Genetics Engineer 52

The Pharma Data

MARCH 18, 2022

Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Using Bacteria For Therapy. ” The Ideal Bacteria.

Bacteria 52

Bacteria Engineer Drugs Research 52

Scienmag

OCTOBER 12, 2020

Potential new antibiotics work by disrupting bacterial membrane and summoning immune cells in animal models PHILADELPHIA–A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

Bacteria 40

Bacteria Engineer Scientist Medicine 40

BioTech 365

MARCH 2, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Common bacteria modified to make designer sugar-based drug.Envisioning an animal-free drug supply, scientists have—for the first time—reprogrammed a common bacterium to make a designer polysaccharide molecule used … Continue (..)

Bacteria 40

Bacteria Bacterium Drugs Scientist 40

Scienmag

MARCH 15, 2022

Pathogens don’t always work against drug treatments. Diseases caused by a combination of bacteria, viruses, fungi and parasites — also known as polymicrobial infections — are challenging to treat because scientists don’t fully understand how pathogens interact during infection and how these […].

Bacteria 58

Bacteria Drugs Scientist 58

pharmaphorum

OCTOBER 7, 2020

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. million) Nobel Prize award. “In

Gene Editing 105

Gene Editing Bacteria DNA Gene 105

STAT News

NOVEMBER 14, 2022

In this video, we chat with health policy and drug pricing researcher Hussain Lalani; Julia Joung, a molecular biologist developing genetic screening technologies; and Avinash Manjula Basavanna, who researches engineered living materials and has developed a printable ink made from bacteria.

Bacteria 96

Bacteria Engineer Genetics Research 96

Delveinsight

JANUARY 28, 2021

Nirogy plans to use the proceeds to improve its drug discovery platform for generating a pipeline of small-molecule drugs designed to aim the solute carrier family of transporter proteins (SLCTs) embedded in the cell membrane. Iterum Therapeutics presents new drug application to FDA for Oral Sulopenem. Nirogy Therapeutics Inc.,

Bacteria 52

Bacteria Trials Drugs Clinical Trials 52

XTalks

JANUARY 6, 2021

Related: Scientists Use Llama Antibodies to Neutralize COVID-19. Nanobodies are attractive therapeutic agents because of their small size and simple structure, which allow them to be more easily used as templates to design antibody drugs compared to human antibodies.

Antibody 105

Antibody Protein Bacteria In-Vitro 105

pharmaphorum

SEPTEMBER 14, 2020

If you are developing a drug, for example, for infantile epilepsy, then you need to know if your drug target is expressed in the brain and also during early development. Likewise, some patients may have a different version of a gene with respect to people on whom a drug has been tested, which means that drug might not work.”.

Genomics 119

Genomics Genome Medicine Gene 119

Delveinsight

JULY 27, 2021

Various Active Pharmaceuticals & Biotechnological Companies including Cassava Sciences, INmune Bio, Cognito Therapeutics, Cortexyme among others presented their new and upcoming drugs, therapies, shared their research studies and clinical data. An Awaited Ulcerative Colitis Phase 2 Seres Therapeutics Trial Drug Crashed Down.

Vaccine 96

Vaccine Vaccination Trials Manufacturing 96

XTalks

JUNE 1, 2022

Osteomyelitis is a bone infection caused by fungi or bacteria. BONESUPPORT has recently received market authorization from the US Food and Drug Administration (FDA) for Cerament G, its bone graft with antibiotic elution. Professor Lidgren is a well renowned orthopedic clinician, researcher and scientist.

Filler 98

Filler FDA Approval Production Marketing 98

Druggist

MARCH 11, 2021

Many drugs can cause dry mouth. This side effect is sometimes associated with the whole class of medicines rather than a particular drug, making dry mouth management even more critical, as there may be little room for changing the medication. List of common drugs that cause dry mouth. List of common drugs that cause dry mouth.

Production 97

Production Containment Pharmacy Sales 97

XTalks

NOVEMBER 3, 2023

After spending almost an entire day deliberating the safety of Vertex Pharmaceuticals’ and CRISPR Therapeutics’ CRISPR-based gene therapy exa-cel for sickle cell disease, a US Food and Drug Administration (FDA) advisory panel appears to be satisfied with what it saw. CRISPR works as genetic scissors to edit parts of the genome.

Gene Therapy 59

Gene Therapy Gene Gene Editing In-Vivo 59

The Pharma Data

DECEMBER 15, 2020

Many drug makers are investing in new science and hope to develop new therapeutics that address autoimmune disease. Scientists will be testing a drug class targeting the C-reactive protein (CRP) marker of acute inflammation in the body. They’ll use software that searches available drugs, as well as drug-like compounds.

Clinical Trials 52

Clinical Trials Clinical Trials Antibody Trials 52

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 28, 2023

Golden staph are ubiquitous bacteria, living harmlessly on the skin or inside the nose of nearly one in three people worldwide. Some strains are also drug-resistant ‘superbugs,’ armed with features […] Yet they are duplicitous, too.

Scientist 246

Scientist Bacteria Drugs Clinical Trials 246

Roots Analysis

OCTOBER 19, 2023

Bacteria plays a crucial role in maintaining the ecosystem balance. However, there are few species of bacteria that can cause several infectious diseases ( such as strep throat, salmonellosis, tuberculosis, whooping cough ). The overuse of antibiotics has resulted in the emergence of multi-drug-resistant bacteria.

Bacteria 40

Bacteria Production In-Vivo In-Vitro 40

Pharmaceutical Technology

MARCH 24, 2023

TB is caused by the bacillus Mycobacterium tuberculosis and is transmitted when infected individuals expel bacteria into the air (e.g., In light of World TB day on March 24, the field hopes to overcome some major barriers to the drug development landscape. by coughing). million new cases reported worldwide.

Vaccine 162

Vaccine Vaccination Clinical Trials Clinical Trials 162

XTalks

JUNE 21, 2024

The US Food and Drug Administration (FDA) has green-lighted the first pneumonia vaccine specifically designed for adults 50 years of age and older. Related: Pneumococcal Vaccination for Adults: Conversation with Vaccine Scientists Dr. Heather Platt and Dr. Ulrike Buchwald from Merck – Xtalks Life Science Podcast Ep.

FDA Approval 108

FDA Approval Vaccine Vaccination Life Science 108

The Pharma Data

JANUARY 4, 2021

Improper disposal of antibiotics also releases these drugs into the environment, and researchers working with these drugs in the lab also have concern over their ultimate effects on study results. ” The use of low-concentration fluoride costs only about four cents per liter. ” Source link.

Bacteria 52

Bacteria Engineer Genetics Genetic Engineering 52

The Pharma Data

JUNE 22, 2023

” The team demonstrated that life-threatening clotting could be prevented in mice infected with the bacteria E. They have shown that the mechanism involves a block in proteins called interferons, which promote tissue factor releases. coli and Staph aureus and also in response to SARS-CoV2, the virus that causes COVID-19.

Bacteria 40

Bacteria Branding Protein Scientist 40

Delveinsight

JULY 23, 2020

Olema Oncology will assess the drug, a complete estrogen receptor antagonist, in patients with ER-positive, HER2-negative breast cancers that have come back despite other treatments or that have spread locally or to other parts of the body. The capital will bankroll a phase 1/2 study of the asset, OP-1250, as a single agent.

Protein 52

Protein Bacteria Scientist Research 52

XTalks

AUGUST 17, 2022

The US Food and Drug Administration (FDA) recognizes National Immunization Awareness Month as providing “an opportunity to think about how far the development and advancement of immunization science has come, and its impact on public health.”. Related: Menarini Diagnostics’ New COVID-19 Test Detects Variants Including Omicron.

Vaccine 98

Vaccine Vaccination Bacteria Development 98

The Pharma Data

SEPTEMBER 27, 2021

Food and Drug Administration (FDA), and to the ecu Medicines Agency (EMA) for the treatment of adults with moderately to severely active colitis , who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biologic agent. RINVOQ 15 mg is approved within the U.S.

Bacteria 52

Bacteria Medicine Development Scientist 52

pharmaphorum

NOVEMBER 25, 2020

The revelation means that the stronger regimen could be added to a growing list of medicines discovered by accident – Alexander Fleming famously discovered penicillin after noticing a mould producing the compound was killing bacteria in a petri dish.

Vaccine 119

Vaccine Vaccination Bacteria RNA 119

The Pharma Data

MAY 15, 2021

Meaning that a natural, drug-free remedy for gout is already known. I started with the standard meds: anti-inflammatories, steroid jabs, drugs to reduce the uric acid in my blood…. But even when a drug did do some good I knew I was just managing the condition. Scientists have long known food is a medicine.

Bacteria 52

Bacteria Doctors Doctor Production 52

XTalks

NOVEMBER 25, 2022

There are several strains of bacteria that have developed resistance to different types of antibiotics — these include MRSA (methicillin-resistant Staphylococcus aureus ) Clostridium difficile ( C. diff ) and the bacteria that cause multi-drug-resistant tuberculosis. According to the WHO, the silent pandemic leads to at least 1.3

Bacteria 98

Bacteria Life Science Development Production 98

The Pharma Data

MAY 15, 2021

Now that scientists know what causes HCT we finally have the power to directly influence those causes. Which meant taking drugs that bind with excess iron in the blood. The chemicals in the drug make the iron less harmful – and so easier to eliminate from the body. And it’s gut bacteria that sits at the root of our HCT problem.

Bacteria 52

Bacteria Gene Gene Therapy Gene Expression 52

Advarra

OCTOBER 10, 2024

Some have argued bacteria are developing antibiotic resistance faster than we can research, develop, test and approve new antibiotics. One possible solution to antibiotic resistance: bacteriophages (or phages), which are viruses that infect bacteria. Antibiotic resistance is an emerging problem.

Bacteria 52

Bacteria Genetics Genetic Engineering Gene 52

Druggist

SEPTEMBER 15, 2021

But, the way the virus is continuously mutating, is a problem for both scientists and doctors. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. An ICMR official warned about the use of this drug in the year 2020.

Doctor 52

Doctor Doctors Medicine Bacteria 52

Druggist

SEPTEMBER 15, 2021

But, the way the virus is continuously mutating, is a problem for both scientists and doctors. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. An ICMR official warned about the use of this drug in the year 2020.

Doctor 52

Doctor Doctors Medicine Bacteria 52

XTalks

AUGUST 2, 2023

Pfizer’s Top 5 Best-Selling Drugs of 2022: 1) Comirnaty Comirnaty is an mRNA-based vaccine indicated for the prevention of COVID-19. Comirnaty was first approved by the US Food and Drug Administration (FDA) in August 2021 for individuals over the age of 16. billion the drug generated in 2021. billion in 2022. billion, a 26.55

Sales 98

Sales Manufacturing FDA Approval Life Science 98

The Pharma Data

MARCH 17, 2021

Food and Drug Administration (FDA) has extended the review period for the supplemental New Drug Application (sNDA) for upadacitinib in the treatment of adult patients with active psoriatic arthritis. The updated Prescription Drug User Fee Act (PDUFA) action date has been extended three months to late Q2 2021.

Drugs 52

Drugs Medicine Bacteria Vaccine 52

The Pharma Data

APRIL 3, 2021

Food and Drug Administration (FDA) has extended the review period for the supplemental New Drug Application (sNDA) for upadacitinib in the treatment of adults and adolescents with moderate to severe atopic dermatitis. The Prescription Drug User Fee Act (PDUFA) action date has been extended three months to early Q3 2021. .

Drugs 52

Drugs Medicine Bacteria FDA Approval 52

The Pharma Data

FEBRUARY 22, 2021

1 The increases in blood creatine phosphokinase were non-serious and did not lead to study drug discontinuation. Discovered and developed by AbbVie scientists, RINVOQ is an oral, once daily, selective and reversible JAK inhibitor studied in several immune-mediated inflammatory diseases. 1 Serious adverse events occurred in 3.2

Medicine 52

Medicine Development Drugs Trials 52

The Pharma Data

JUNE 28, 2021

Food and Drug Administration (FDA) has informed the company that the FDA will not meet the Prescription Drug User Fee Act (PDUFA) action dates for the supplemental New Drug Applications (sNDAs) for RINVOQ ® (upadacitinib) for the treatment of adults with active psoriatic arthritis and adults with active ankylosing spondylitis. .

Medicine 52

Medicine Drugs Bacteria FDA Approval 52