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Salt stress alters legume responses to symbiotic rhizobacteria by modulating gene expression

Scienmag

Crop legumes are an integral part of sustainable agriculture, as several of these species represent an important protein source for both human and animal populations. Legumes engage in a unique and beneficial interaction with a group of soil bacteria, collectively called rhizobia.

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The untapped potential of the transcriptome  

Drug Discovery World

The transcriptome, unlike static DNA sequences, is a dynamic and complex target in drug discovery, reflecting real-time changes in gene expression across different conditions and tissues. The transcriptome (RNA) enables us to target classically undruggable proteins such as c-MYC, which is the driver for 40% of cancers 2.

RNA 64
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Gene Therapy and Pharmacokinetics

Camargo

The technology of gene therapy is possible due to extensive DNA research and our resulting understanding of many diseases on the genetic level, and it encompasses several mechanisms such as introducing new genes (gene addition) and inactivating or replacing mutated genes (gene editing).

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. Abell Chair in Molecular and Cellular Biology – and Pengbo Cao, a postdoctoral researcher in Whiteley’s lab, discovered a gene that drives the switch.

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Biologics – The Next Step in Revolutionary Medication

Roots Analysis

Biologics activate certain proteins or cells in your immune system to create specific responses to targets, while many conventional systemic drugs activate the entire immune system in a more generalized manner. It is worth mentioning that in vitro gene expression requires a suitable host for the production of a specific gene product.

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Women in Science Who Have Paved the Way Forward in Genetics

XTalks

The Hershey-Chase experiment is the historic study that solidified DNA as the carrier of genetic information over protein. At the same time, it was thought that protein was the carrier of genetic information as DNA was too inert of a substance — and was also shielded away in the nucleus — to be able to harbor such a role. Martha Chase.

Genetics 119
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2020 Year in Review: COVID-19, CRISPR and Immunotherapies Define the Year for the Life Sciences

XTalks

SARS-CoV-2 is characterized by an outer surface speckled with spike proteins, giving it a crown-like appearance, hence the name “corona,” which is the Latin word for crown. The spike protein is critical for binding to ACE2 receptors on host cells — this interaction mediates the entry of the virus into cells.