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CRISPR’s deal with Nkarta aims to create geneticallyengineered NK cells, which are harvested and used to create a bank of “off the shelf” cells that can administered to patients like a drug. Nkarta also gets a license to CRISPR gene editing to an unlimited number of its own NK cell therapy products.
These mAbs are already of human origin and functionally optimized for high potency by the donor’s immune system; hence, they technically do not require geneticengineering or further optimization to achieve full functionality. AR-711 (COVID-19). AR-201 (RSV infection).
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