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Bacteria integrate genetic material from other bacterial strains more easily than previously thought, which can lead to improved fitness and accelerated evolution. The team analysed genome transfer between bacteria of different lineages. This is shown in a recent study by biophysicists at the University of Cologne.
Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential.
The spread of antibiotic resistant bacteria in hospitals could be greatly reduced thanks to research by The University of Queensland and Queensland Health.
Researchers take a closer look at the genomes of microbial communities in the human mouth Credit: Photo credit: Jessica Mark Welch, Marine Biological Laboratory.
The shortlist includes researchers who elucidated how cells make energy, those who discovered the chemical chatter of bacteria, many of the brilliant minds who shepherded us into the “ era of the genome ,” and most prominently, the pioneers behind the mRNA Covid vaccines. Read the rest…
It’s a new genetic way of potentially targeting these really hard to treat diseases,” said Abudayyeh, a McGovern Fellow at MIT’s McGovern Institute for Brain Research, in MIT’s press release. Integrases are used by viruses called bacteriophages to insert their genetic material into bacteria.
Work allows genomic monitoring for epidemic strains of Vibrio cholerae bacteria The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the (..)
Collaborative efforts, from genomic surveillance (for tracking pathogen mutations, helping to predict variants and guide vaccine updates) to climate change mitigation, have shown measurable success.
A naturally occurring system for tuning CRISPR-Cas9 expressing in bacteria, identified in a study published in Cell , could have implications for gene editing therapies as well. In bacteria with unaltered tracr-L, levels of CRISPR-related genes were low. The authors found that tracr-L redirects Cas9 in S.
New Class of Antibiotic Works Against Range of Bacteria. They focused on a metabolic pathway essential for bacteria but absent in humans, called methyl-D-erythritol phosphate (MEP) or non-mevalonate pathway, which is responsible for biosynthesis of isoprenoids. Isoprenoids are required for cell survival in most pathogenic bacteria.
WHO launches global network to detect and prevent infectious disease threats WHO and partners are launching a global network to help protect people from infectious disease threats through the power of pathogen genomics. COVID-19 highlighted the critical role pathogen genomics plays in responding to pandemic threats.
We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. In doing so, they induce epigenetic changes.
CRISPR works as genetic scissors to edit parts of the genome. The CRISPR-Cas9 gene editing system was first discovered to be endogenous in bacteria. The companies used data from the 1,000 Genomes Project but from that, only 61 datasets made the cut to encompass the ideal patient population. “I
Respiratory infections are caused by a good sort of pathogens, like influenza viruses, respiratory syncytial virus, parainfluenza viruses, metapneumovirus, rhinovirus, enterovirus, coronavirus and adenovirus, and other bacteria pathogens. Source link: [link].
By leveraging the comprehensive genomic, transcriptomic and proteomic profiling available through the Caris Molecular Intelligence® platform, physicians from Winship will be able to further prioritize therapeutic options and determine which clinical trial opportunities may benefit their patients. Brille , Vice Chairman of Caris Life Sciences.
The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two. Rosalind Franklin.
From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. Infectious disease expert, epidemiologist and director of the Yale Institute for Global Health at Yale University, Saad B.
Some have argued bacteria are developing antibiotic resistance faster than we can research, develop, test and approve new antibiotics. One possible solution to antibiotic resistance: bacteriophages (or phages), which are viruses that infect bacteria. Bacteriophages (phages for short) are viruses that infect bacteria.
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