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Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. If you look at a region that is repeated or deleted, by, for example, 10,000 nucleotides in length and you’ve got a tiny read, you can’t match that to the genome with any confidence.”.
CRISPR works as genetic scissors to edit parts of the genome. The CRISPR-Cas9 gene editing system was first discovered to be endogenous in bacteria. The companies used data from the 1,000 GenomesProject but from that, only 61 datasets made the cut to encompass the ideal patient population. “I
The Human GenomeProject recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.
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