Pharmaceutical Technology

APRIL 26, 2023

Co-led by new investors the AMR Action Fund and AXA IM Alts, the investment syndicate also included existing investors Reimagined Ventures, the Bill & Melinda Gates Foundation, Atlantic Neptune, Fiscus Ventures, PEAK6 and Skyviews Life Science.

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Bacteria Life Science Trials Medicine 130

XTalks

AUGUST 26, 2020

Increasing research into the gut microbiome has revealed new and emerging roles for the ‘good bacteria’ in our bodies, with the latest being a new study that shows how they can help the immune system attack cancer cells. The findings were published in the journal Science.

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Bacteria Research Immune Response Scientist 52

Scienmag

FEBRUARY 7, 2022

In a landmark study of airborne microorganisms from ground level up to 3,500 metres, scientists from the Singapore Centre for Environmental Life Sciences Engineering (SCELSE) at Nanyang Technological University, Singapore (NTU Singapore) have found that bacteria and fungi populate the planet’s lower atmosphere in very specific ways and if changed, (..)

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Bacteria Life Science Engineer Scientist 77

Scienmag

FEBRUARY 5, 2021

Membrane-localized phage proteins may also help revitalize, enhance existing antibiotics A study from the Center for Phage Technology, part of Texas A&M’s College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the “hidden” genes in bacteriophages — types of viruses that infect and destroy (..)

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Gene Bacteria Life Science Development 74

pharmaphorum

OCTOBER 7, 2020

Charpentier – currently at the Max Planck Unit for the Science of Pathogens in Germany – and Doudna of the University of California, Berkeley (pictured left to right), are the first two women to share the prize awarded by the Royal Swedish Academy of Sciences. — The Nobel Prize (@NobelPrize) October 7, 2020.

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Gene Editing Bacteria DNA Gene 105

XTalks

APRIL 28, 2021

Research involving rats has identified a mechanistic link between high sugar consumption and impaired learning and memory later in life that involves a specific genus of gut bacteria. Subscribe to the Xtalks Life Science Podcast to never miss a new episode. How Sugar May Impair Brain Development in Children.

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Life Science Vaccination Vaccine Development 40

Drug Discovery Today

OCTOBER 7, 2024

Researchers from the Institute of Biotechnology at the Life Sciences Center of Vilnius University – Dalia Smalakyte, Audrone Rukšenaite, Dr Giedrius Sasnauskas, Dr Giedre Tamulaitiene, and Dr Gintautas Tamulaitis – have revealed the structure of the CRISPR-Cas "protein scissors" found in bacteria and provided mechanistic details on how they function. (..)

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Protein Bacteria Life Science Research 45

XTalks

OCTOBER 29, 2024

Although UTIs are often straightforward to treat, they are commonly caused by strains of bacteria increasingly resistant to traditional antibiotics, such as amoxicillin and ciprofloxacin. uUTIs affect millions in the US each year and primarily affect women.

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FDA Approval Bacteria Clinical Trials Clinical Trials 105

XTalks

OCTOBER 29, 2024

Although UTIs are often straightforward to treat, they are commonly caused by strains of bacteria increasingly resistant to traditional antibiotics, such as amoxicillin and ciprofloxacin. uUTIs affect millions in the US each year and primarily affect women.

FDA Approval 98

FDA Approval Bacteria Clinical Trials Clinical Trials 98

XTalks

AUGUST 26, 2020

Macrophages are white blood cells that specialize in the detection, phagocytosis and destruction of bacteria and other harmful organisms. In other words, when fighting bacteria, the macrophages are programmed to be pro-inflammatory. However, when they are programmed to be anti-inflammatory, they can help decrease inflammation.

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Bacteria Immune Response Protein Medicine 105

XTalks

NOVEMBER 28, 2023

Following passive diffusion into the organism, metronidazole is activated in the cytoplasm of susceptible anaerobic bacteria through reduction. The reduced form of metronidazole, along with free radicals, interacts with DNA, inhibiting DNA synthesis and causing DNA degradation, ultimately leading to the demise of the bacteria.

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FDA Approval Bacteria DNA Drugs 103

pharmaphorum

JUNE 9, 2022

Not to mention that traditional antibiotics are designed to attack a broad spectrum of bacteria within the host’s body. These include the harmful bacterial pathogens that cause an infection, but also the beneficial bacteria which are part of the human microbiome and are essential for good health. About Micreos Pharmaceuticals.

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Bacteria Development In-Vitro Drugs 104

XTalks

JUNE 21, 2024

Related: Pneumococcal Vaccination for Adults: Conversation with Vaccine Scientists Dr. Heather Platt and Dr. Ulrike Buchwald from Merck – Xtalks Life Science Podcast Ep. 140 Other companies are also gearing up for their own adult-targeted pneumococcal vaccines.

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FDA Approval Vaccination Vaccine Life Science 108

XTalks

APRIL 22, 2021

They specifically found that consuming excess sugar early on in life leads to an increase in levels of Parabacteroides bacteria. Related: Research Shows How Gut Bacteria Can Help Fight Cancer. The researchers found that the cognitive impairments were associated with changes in the gut microbiota induced by high sugar levels.

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Development Bacteria Research Regulation 76

XTalks

MAY 31, 2024

The FDA’s decision was based on robust clinical data demonstrating Exblifep’s efficacy against antimicrobial resistance in gram-negative bacteria, particularly resistance associated with extended-spectrum beta-lactamases and ampC enzymes. What are cUTIs? However, Enterococcus spp. and Candida spp. The success rate was 79.1

Bacteria 52

Bacteria FDA Approval Trials Drugs 52

XTalks

JULY 28, 2021

Merck has scored US Food and Drug Administration (FDA) approval for its next-generation pneumonia vaccine Vaxneuvance that covers 15 different strains of the pneumococcal bacteria that causes the infection. Both next-gen shots offer enhanced protection against bacteria that can cause pneumonia, blood infections and meningitis.

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FDA Approval Vaccination Vaccine Immune Response 89

XTalks

NOVEMBER 25, 2022

There are several strains of bacteria that have developed resistance to different types of antibiotics — these include MRSA (methicillin-resistant Staphylococcus aureus ) Clostridium difficile ( C. diff ) and the bacteria that cause multi-drug-resistant tuberculosis. According to the WHO, the silent pandemic leads to at least 1.3

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Bacteria Life Science Development Production 98

XTalks

DECEMBER 23, 2024

Meanwhile, researchers advanced alternative therapies to combat antimicrobial resistance, targeting drug-resistant bacteria with novel antibiotics. This test, which enables the rapid detection of multi-drug-resistant tuberculosis, is expected to significantly improve early diagnosis rates globally.

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Vaccination Vaccine Containment Bacteria 52

XTalks

JULY 6, 2021

CDIs usually develop after treatments with antibiotics as they can kill off healthy bacteria in the gut in the process of targeting the pathogenic bacteria. Firmicutes microbes are an important protective species in the gut and are also involved in the life cycle of C. Related: How Sugar May Impair Brain Development in Children.

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Marketing Drugs Bacteria FDA Approval 105

XTalks

JULY 14, 2021

CDIs typically develop after the use of antibiotics, which can wipe out the gut’s healthy bacteria. Seres’ microbiome drug SER-109 aims to restore the healthy bacteria via an oral capsule that contains a protective species of gut bacteria. Difficile infection (CDI).

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Bacteria Marketing Drugs Containment 52

XTalks

DECEMBER 12, 2023

The drug will have a boxed warning for increased risk of “life-threatening infections caused by encapsulated bacteria.” Given this, Fabhalta will be made available through a Risk Evaluation and Mitigation Strategy (REMS) program that requires vaccinations for encapsulated bacteria.

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FDA Approval Bacteria Trials Protein 95

XTalks

DECEMBER 14, 2022

Integrases are used by viruses called bacteriophages to insert their genetic material into bacteria. “Just like CRISPR, these integrases come from the ongoing battle between bacteria and the viruses that infect them,” said Jonathan Gootenberg, also a McGovern Fellow. percent of these cells. ” The Future of PASTE.

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Gene Editing DNA Gene Gene Sequencing 98

XTalks

DECEMBER 2, 2022

difficile as certain antibiotics can disrupt the balance of bacteria in the gut, allowing bacteria like C. While Rebyota is the first of its kind pharmaceutical therapy, the concept of healing the gut via fecal matter-derived bacteria is not new. The use of certain antibiotics can contribute to infection caused by C.

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FDA Approval Bacteria Clinical Trials Clinical Trials 59

XTalks

JANUARY 22, 2021

It identifies bacteria using both genotypic and phenotypic assessments within 1.5 Empirical treatment usually gives two to three antibiotics at the same time to suppress unknown bacteria.”. fAST: Automated Bacteria Identification and Multiple Antibiotics Combination Test.

Bacteria 52

Bacteria In-Vitro Genotype Marketing 52

XTalks

JANUARY 6, 2021

Owing to their size, they can be grown in bacteria as opposed to larger animal or human cells, making them easier and cheaper to produce. These regions play a crucial role in the detection of antigens on viruses, bacteria and other pathogens. Several groups have been researching nanobodies as treatment options for COVID-19.

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Antibody Protein Bacteria In-Vitro 105

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .

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Life Science Clinical Trials Clinical Trials RNA 52

XTalks

AUGUST 28, 2020

Egorov told Xtalks that, “many studies being carried out right now show that one of the major ways that people get infected with COVID or any other virus or bacteria is not by sharing the bacteria [directly] by sneezing or coughing, but by [touching surfaces], holding hands and then rubbing the nose and eyes.

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Containment Bacteria Marketing Production 111

XTalks

AUGUST 2, 2022

The autoantibodies do not fight actual infection or bacteria, but rather the normal tissue in the body. In those affected by lupus, autoreactive B cells (those that react against the body), remain in the body long after the “threat” to the immune system is gone. When this behaviour is prolonged, it results in inflammation.

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FDA Approval Antibody Bacteria Protein 94

XTalks

AUGUST 18, 2021

Also important are the environmental changes that take place in the lung tissue during infection with SARS-CoV-2; the buildup of fluid and pus in pulmonary alveoli can provide a hospitable breeding ground for pathogenic bacteria. This is consistent with autopsy reports from previous pandemics, including the influenza pandemic of 1918.

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Development Bacteria Drugs Vaccine 105

XTalks

OCTOBER 14, 2022

Whooping cough , also known as pertussis, is a highly contagious respiratory infection caused by the Bordetella pertussis bacteria. The vaccine is a Tdap vaccine (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) that can be administered during the third trimester of pregnancy.

FDA Approval 98

FDA Approval Vaccination Vaccine Protein 98

XTalks

MAY 31, 2022

Tapinarof was discovered as an outcome of investigations into the secondary metabolites of Photorhabdus luminescens, a bioluminescent, Gram-negative bacteria. There is 10 mg of tapinarof per gram of Vtama cream. XTALKS WEBINAR: All Means All: The Road to Inclusivity in Clinical Trials.

FDA Approval 98

FDA Approval Clinical Trials Clinical Trials Trials 98

XTalks

NOVEMBER 4, 2020

It has long been known that mothers greatly influence the development of the growing fetus by not only providing nutrients through the placenta, but also a growing list of biological elements including beneficial antibodies, gut bacteria and now, allergies.

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Allergies Antibody In-Vitro Development 98

XTalks

JUNE 1, 2022

Osteomyelitis is a bone infection caused by fungi or bacteria. BONESUPPORT received market authorization from the FDA for Cerament G, the first and only bone graft with antibiotic elution that is approved for the US market.

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Filler FDA Approval Production Marketing 98

XTalks

AUGUST 9, 2023

By focusing on the removal of excess bacteria, biofilm and bacterial toxins — the chief culprits behind eyelid symptoms — BlephEx presents a potent solution for those looking for symptom relief. Beyond this cleanser, the FDA has endorsed an in-office procedure named BlephEx.

FDA Approval 98

FDA Approval In-Vitro Trials Bacteria 98

XTalks

JULY 25, 2023

The bacteria usually enter the body through wounds, but infection can also occur through contaminated meat or inhalation of spores. Anthrax is a rare, yet severe disease caused by the bacterium B. anthracis , primarily affecting livestock and wild game.

FDA Approval 98

FDA Approval Vaccination Vaccine Antibody 98

XTalks

JUNE 14, 2022

FL OZ (9 mL) nasal spray bottles to be contaminated with the bacteria, Providencia rettgeri. California-based Green Pharmaceuticals Inc. is recalling the 2372/21222 lot of their SnoreStop NasoSpray bottles. The US Food and Drug Administration (FDA) found the 0.3

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Contamination Bacterium Bacteria Branding 52

XTalks

AUGUST 17, 2022

As individuals get older, it becomes just as critical for them to keep up with required vaccinations to help protect against illnesses that can become life threatening as the immune system becomes weaker with age.

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Vaccination Vaccine Bacteria Development 98