XTalks

NOVEMBER 9, 2021

And unlike chemical pesticides, RNAi functions to prevent an essential protein from being made in the first place. Since pathogens and pests are the largest threat to agriculture production, some studies suggest that RNAi can be used to silence essential gene functions in pathogenic microbes, which can be viruses, bacteria or fungi.

RNA 98

RNA Gene Scientist Protein 98

XTalks

APRIL 17, 2023

While food safety regulations and advances in technology have greatly reduced the incidence of such events, some of the worst food safety incidents continue to occur. coli O157:H7 bacteria. As a result, Chipotle was forced to temporarily close dozens of its restaurants across the country to prevent further spread of the bacteria.

Contamination 98

Contamination Bacterium Production Regulation 98

XTalks

AUGUST 26, 2024

Protein content is another significant issue. The study found that 70 percent of the products failed to meet the WHO’s protein guidelines, while 25 percent did not meet calorie recommendations. Related: Cronobacter Sakazakii: The Bacteria Behind the Baby Formula Shortage One of the most alarming findings relates to sugar content.

Containment 52

Containment Production Regulation Protein 52

pharmaphorum

AUGUST 7, 2020

LRRK2 regulates lysosomes, which play a vital role in cell function by breaking down excess or worn-out cell parts, and can also destroy invading viruses and bacteria. A molecule codenamed DNL151, currently in phase 1 development, has been selected to progress into late stage clinical studies that are expected to begin in 2021.

Bacteria 69

Bacteria Marketing Licensing Licensing 69

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. Most current technology actually focuses on looking at the bits of the genome that produce proteins.

Genome 119

Genome Genomics Medicine Gene 119

Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Further, the expression of any gene is dependent on the rate at which it is transcribed into mRNA and translated into proteins. When activator binds to the operon, it either speeds up or permits gene expression.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

pharmaphorum

APRIL 26, 2022

The news is a timely boost for Paris, France-based Valneva, which is facing uncertain prospects for its COVID-19 vaccine after the EU regulator requested more data on the latecomer candidate this week despite a UK approval earlier in April.

Vaccination 69

Vaccination Vaccine Bacteria Trials 69

Roots Analysis

JANUARY 14, 2024

Like all drugs, biologics are regulated by the FDA. Biologics activate certain proteins or cells in your immune system to create specific responses to targets, while many conventional systemic drugs activate the entire immune system in a more generalized manner. coli is relatively easy compared to other strains of bacteria.

Contract Manufacturing 40

Contract Manufacturing Protein Manufacturing Production 40

The Pharma Data

MARCH 13, 2022

CD8+ T cells are nicknamed killer T cells (they’re also known as cytotoxic T cells) for their ability to eliminate foreign invaders such as bacteria and viruses from the body. “We only found one low-prevalence epitope from the omicron spike protein that had a minor change from its predecessor in the original virus,” says Redd.

Immune Response 52

Immune Response Protein Medicine Genetics 52

Roots Analysis

OCTOBER 16, 2023

Once isolated, molecular clones can be used to generate multiple copies of DNA for the analysis of gene sequences and / or to express proteins obtained for the study or utilization of protein function. These clones can be manipulated and mutated in vitro to alter the expression and function of a protein.

DNA 40

DNA Gene Protein In-Vitro 40

XTalks

APRIL 12, 2021

GBA1 encodes for beta-glucocerebrosidase (GCase), a lysosomal enzyme that is responsible for regulating the organelle’s ability to get rid of glycolipids. Despite being implicated in many cases of Parkinson’s disease, the function of LRRK2 is not fully understood, though it’s thought to regulate lysosomal function.

Gene Therapy 96

Gene Therapy Gene Trials Development 96

The Pharma Data

OCTOBER 19, 2020

In a challenge trial, people are given a vaccine then intentionally dosed with the virus or bacteria that causes the disease. The vaccine candidate is called “spike ferritin nanoparticle” (SpFN) and uses ferritin— “attaching a certain type of spike protein to a polymerized version of ferritin,” according to the organization.

Vaccination 52

Vaccination Vaccine Trials Clinical Trials 52

The Pharma Data

OCTOBER 19, 2020

There are more than 90 different types of pneumococcal bacteria which can affect adults differently than children. The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. Plans for global regulatory licensure applications, beginning with the U.S.

Vaccine 52

Vaccine Vaccination Immune Response Containment 52

The Pharma Data

DECEMBER 15, 2020

Scientists will be testing a drug class targeting the C-reactive protein (CRP) marker of acute inflammation in the body. The protein may be involved in such conditions, and a CRP test may be used to find or monitor conditions that cause inflammation. These include inflammatory bowel disease, lupus or rheumatoid arthritis.

Clinical Trials 52

Clinical Trials Clinical Trials Antibody Trials 52

XTalks

AUGUST 2, 2023

Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease. The monoclonal antibody targets CD20, a protein found on the surface of B lymphocytes (B cells).

Sales 98

Sales Manufacturing FDA Approval Life Science 98

XTalks

DECEMBER 24, 2020

SARS-CoV-2 is characterized by an outer surface speckled with spike proteins, giving it a crown-like appearance, hence the name “corona,” which is the Latin word for crown. The spike protein is critical for binding to ACE2 receptors on host cells — this interaction mediates the entry of the virus into cells. Vaccine Considerations.

Life Science 111

Life Science Vaccination Vaccine Gene 111

The Pharma Data

MAY 14, 2021

Charles River loses a battle over harvesting horseshoe crabs used for testing bacteria in drugs ( STAT ). After going down different drug discovery paths, Genentech vets reunite at Foresite Labs to map the ‘protein interactome’ ( Endpoints ). In Focus: International. Medtech.

Gene Therapy 52

Gene Therapy Gene Vaccination Vaccine 52