Camargo

JULY 27, 2021

Gene therapy, which was in its infancy around 30 years ago, is now becoming a more prominent treatment method in many therapeutic areas, from personalized therapy to mass vaccinations against COVID-19.

Gene Therapy 238

Gene Therapy Gene Gene Editing Genetics 238

XTalks

OCTOBER 14, 2022

Boostrix is the first vaccine in the US indicated for the protection of newborns under two months of age from pertussis. The vaccine is a Tdap vaccine (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) that can be administered during the third trimester of pregnancy.

FDA Approval 98

FDA Approval Vaccine Vaccination Protein 98

Pfizer

FEBRUARY 16, 2023

who had been enrolled in the Vaccine Against Lyme for Outdoor Recreationists (VALOR) (NCT05477524) Phase 3 clinical study. The study is investigating the efficacy, safety and immunogenicity of an investigational Lyme disease vaccine candidate, VLA15. OspA is a surface protein expressed by the bacteria when present in a tick.

Clinical Trials 76

Clinical Trials Clinical Trials Vaccine Vaccination 76

pharmaphorum

JUNE 20, 2022

stake in French vaccines developer Valneva at a cost of €90.5 VLA15 is the only vaccine for the tick-borne infection in clinical development, and is due to start a phase 3 trials programme in the third quarter of this year, said Pfizer. Pfizer has acquired an 8.1% The UK has approved the COVID shot – but backed out of a $1.5

Vaccination 98

Vaccination Vaccine Licensing Licensing 98

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

In-Vivo 162

In-Vivo Genome Genomics Gene Editing 162

pharmaphorum

MAY 31, 2022

billion takeover of US biotech Affinivax, buying a pneumococcal vaccine candidate that is aiming to break into a market that for years has been dominated by Pfizer’s Prevnar franchise. The post GSK bolsters vaccines division with $3.3bn swoop on Affinivax appeared first on. GlaxoSmithKline has agreed a $3.3

Vaccine 52

Vaccine Vaccination Bacterium Sales 52

The Pharma Data

MARCH 8, 2021

Valneva SE (“Valneva”), a specialty vaccine company focused on prevention of diseases with major unmet needs, and Pfizer Inc. It will compare the three-dose vaccination schedule (Month 0-2-6) with a two-dose schedule (Month 0-6). “We We are excited to be part of the Lyme disease vaccine development program with Valneva.

Vaccine 52

Vaccine Vaccination Bacteria Protein 52

The Pharma Data

APRIL 26, 2022

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, and Pfizer Inc. Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, and Pfizer Inc. NYSE: PFE) today reported positive Phase 2 pediatric data for their Lyme disease vaccine candidate, VLA15.

Vaccine 52

Vaccine Vaccination Bacteria Protein 52

Delveinsight

JULY 26, 2021

Often the bacteria develop antibiotic resistance to certain drugs, leaving it non-effective for the usage the second time in the case of recurrence of the infection that occurs in approximately 30-35% of the uUTI cases, therefore, leaving a serious dearth of the new antibiotics. coli bacteria called FimH.

Marketing 93

Marketing Bacteria Development Vaccination 93

The Pharma Data

JULY 21, 2021

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company focused on the development and commercialization of prophylactic vaccines for infectious diseases with significant unmet medical need, and Pfizer Inc. at Month 7). Juan Carlos Jaramillo M.D.,

Vaccine 52

Vaccine Vaccination Trials Bacteria 52

XTalks

FEBRUARY 11, 2021

Amidst growing global shortages of COVID-19 vaccine supplies, inaugural (by way of authorizations/approvals) COVID-19 vaccine maker Pfizer is addressing the issue by working to cut the manufacturing time of its vaccine by almost half. Related: Pharma Rivals Step Up to Assist with COVID-19 Vaccine Production.

Manufacturing 52

Manufacturing Vaccine Vaccination DNA 52

XTalks

DECEMBER 17, 2021

The year continued to be dominated by COVID-19, and the second year of the pandemic was all about vaccines. And while over 8 billion doses of vaccines have been administered worldwide, billions more are still needed. And while over 8 billion doses of vaccines have been administered worldwide, billions more are still needed.

Life Science 98

Life Science Vaccine Vaccination Trials 98

XTalks

DECEMBER 12, 2023

Less than a week after the approval, Novartis shared results from its APPEAR-C3G Phase III study of patients with C3 glomerulopathy (C3G) that showed iptacopan led to clinically meaningful reduction in proteinuria (protein in the urine) compared to placebo after six months of use.

FDA Approval 95

FDA Approval Bacteria Trials Protein 95

pharmaphorum

APRIL 26, 2022

There’s only one vaccine candidate for tick-borne infection Lyme disease in clinical development – Valneva and Pfizer’s VLA15 – and it has just moved another step closer to being available. There’s no guarantee of revenues for the COVID-19 shot from the UK however as the government there backed out of a $1.5

Vaccine 69

Vaccine Vaccination Bacteria Trials 69

XTalks

NOVEMBER 9, 2021

Perhaps popularized by the COVID-19 vaccines, RNA-based technologies now have the potential to become the next best pesticide to combat crop pests, like insects and fungal pathogens. And unlike chemical pesticides, RNAi functions to prevent an essential protein from being made in the first place. In 2017, Monsanto Co.

RNA 98

RNA Gene Scientist Protein 98

pharmaphorum

JULY 14, 2021

Already facing one rival to its blockbuster pneumococcal vaccine Prevnar, Pfizer could have another to contend with, after Affinivax reported positive phase 2 results with its ASP3772 candidate – plus a new breakthrough designation from the FDA. That is equivalent to 14% of Pfizer’s total revenues.

Immune Response 52

Immune Response Vaccine Vaccination Protein 52

The Pharma Data

OCTOBER 19, 2020

.–( BUSINESS WIRE )– Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced findings from two additional Phase 3 studies evaluating the safety, tolerability and immunogenicity of V114, the company’s investigational 15-valent pneumococcal conjugate vaccine. among adults 65 years of age or older.

Vaccine 52

Vaccine Vaccination Immune Response Containment 52

The Pharma Data

JUNE 18, 2021

First approval of a conjugate vaccine that helps protect against 20 serotypes responsible for the majority of invasive pneumococcal disease and pneumonia, 1,2,3,4,5,6,7 including seven responsible for 40% of pneumococcal disease cases and deaths in the U.S. Senior Vice President and Head of Vaccine Research & Development, Pfizer.

Vaccine 52

Vaccine Vaccination FDA Approval Containment 52

XTalks

DECEMBER 22, 2021

The RNA Revolution: From mRNA Vaccines to RNA Editing. RNA, and its protein-generating form messenger RNA (mRNA) discovered in 1961 , has quickly transitioned from being an obscure, finicky molecule that is difficult to work with, to becoming a significant cornerstone of therapeutic innovation in pharma and biotech.

Life Science 98

Life Science RNA Vaccination Vaccine 98

The Pharma Data

JULY 18, 2021

Food and Drug Administration (FDA) approved VAXNEUVANCE ™ (Pneumococcal 15-valent Conjugate Vaccine) (pronounced VAKS-noo-vans) for active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F and 33F in adults 18 years of age and older.

Immune Response 52

Immune Response Vaccine Vaccination FDA Approval 52

The Pharma Data

OCTOBER 19, 2020

Testing Therapies, Antivirals and Vaccines. There has been some discussion of running challenge trials for COVID-19 vaccines. In a challenge trial, people are given a vaccine then intentionally dosed with the virus or bacteria that causes the disease. They will require regulatory and ethical approval.

Vaccine 52

Vaccine Vaccination Trials Clinical Trials 52

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. Membrane Filters: Membrane filters are typically used for sterilization and removal of smaller impurities such as bacteria and viruses.

Bacteria 40

Bacteria Production Protein Contamination 40

Roots Analysis

JANUARY 14, 2024

With the increased interest and gradual shift of investment from small molecule drugs to biologics and the establishment of several biologics manufacturing companies / biologics CMOs, more than 250 biologic therapies and vaccines have been developed, globally. Examples of prominent microbial expression systems are bacteria, fungi, and yeast.

Contract Manufacturing 40

Contract Manufacturing Protein Manufacturing Production 40

The Pharma Data

MARCH 13, 2022

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. population.

Immune Response 52

Immune Response Protein Medicine Genetics 52

XTalks

AUGUST 2, 2023

With each passing year, pharmaceutical companies around the globe strive to deliver cutting-edge medicines, therapies and vaccines that impact the lives of millions. Pfizer’s Top 5 Best-Selling Drugs of 2022: 1) Comirnaty Comirnaty is an mRNA-based vaccine indicated for the prevention of COVID-19. billion in 2022. for a pediatric dose.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

Roots Analysis

OCTOBER 16, 2023

Once isolated, molecular clones can be used to generate multiple copies of DNA for the analysis of gene sequences and / or to express proteins obtained for the study or utilization of protein function. These clones can be manipulated and mutated in vitro to alter the expression and function of a protein.

DNA 40

DNA Gene Protein In-Vitro 40

Druggist

SEPTEMBER 15, 2021

But these days the vaccines being used to protect against covid are proving to be most effective. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. Every effort is being made to prevent covid-19.

Doctors 52

Doctors Doctor Medicine Bacteria 52

Druggist

SEPTEMBER 15, 2021

But these days the vaccines being used to protect against covid are proving to be most effective. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. Every effort is being made to prevent covid-19.

Doctors 52

Doctors Doctor Medicine Bacteria 52

The Pharma Data

JUNE 30, 2021

To achieve this, she developed a novel ELISA (Enzyme-linked Immunosorbent Assay) to measure a certain antibody type directed towards a specific protein of the virus. “In our study, we measured the humoral response – so the level of antibodies – in naturally exposed cats,” relays Yasmin Parr. We warmly congratulate this year’s winners.”

Scientist 52

Scientist Immune Response Antibody Development 52

XTalks

APRIL 12, 2021

synuclein is a hallmark of Parkinson’s, and it’s been postulated that dysfunction of GCase in neurons could contribute to build-up of the protein and the resulting inflammation and neurodegeneration characteristic of the disorder. Research suggests that some gut bacteria can increase levels of ?-synuclein Cellular accumulation of ?-synuclein

Gene Therapy 96

Gene Therapy Gene Trials Development 96

XTalks

DECEMBER 24, 2020

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. For example, investment in mRNA vaccines and viral vectors came well before January, many years before it.

Life Science 111

Life Science Vaccine Vaccination Gene 111

pharmaphorum

DECEMBER 15, 2020

million (around $56 million) in a Series B funding round to take its novel group B streptococcus (GBS) vaccine into mid-stage clinical trials. MinervaX is one company that wants to change this situation, which aims to prevent the spread of GBS infections using a vaccine instead of using an antibacterial agent.

Bacteria 52

Bacteria Vaccine Vaccination Immune Response 52

The Pharma Data

JANUARY 21, 2021

Pfizer-BioNTech COVID-19 Vaccine Effective Against UK Variant. Pfizer and BioNTech announced that their COVID-19 vaccine was probably just as effective against the variant strain of the virus, B.1.1.7, found in the U.K. Unusual Findings in ALS Population in Malta. How Some Prostate Cancer Cells Become Resistant to Treatment.

Research 52

Research DNA Hormones Vaccination 52

Pharmaceutical Technology

MARCH 24, 2023

Since the first human administration of the Bacillus Calmette-Guérin vaccine in 1921, no one has been able to successfully follow the vaccine’s path to become the next approved vaccine to tackle tuberculosis (TB). However, as the TB-related death toll remains high, the global need for another vaccine is steadily rising.

Vaccine 162

Vaccine Vaccination Clinical Trials Clinical Trials 162

Pharmaceutical Technology

MAY 17, 2023

In addition to revolutionising diabetes care, insulin has become an essential component of biopharmaceutical manufacturing, where its growth-supplementing ­­­properties are relied on to enhance commercially available cell culture media and achieve higher yields of target therapeutic proteins. Can it support the newer therapeutic modalities?

Insulin 130

Insulin Production Manufacturing Contamination 130

XTalks

MARCH 24, 2025

Over time, this leads to proteinuria, where protein leaks into the urine, and eventually to kidney failure. Due to a risk of serious infections from encapsulated bacteria, its use is limited to a Risk Evaluation and Mitigation Strategy requiring specific vaccinations.

Bioavailability 71

Bioavailability Immune Response Protein Bacteria 71

The Pharma Data

MAY 14, 2021

Fully vaccinated people can shed their masks in most places – CDC ( Reuters ) ( STAT ). US diplomats: Send vaccine overseas now or China, Russia will win out ( Politico ). Charles River loses a battle over harvesting horseshoe crabs used for testing bacteria in drugs ( STAT ).

Gene Therapy 52

Gene Therapy Gene Vaccine Vaccination 52