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Credit: SDSU For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.
Credit: (Image: Chair of Molecular Infection Biology II / University of Wuerzburg / SCIGRAPHIX) More than half of the world’s population carries the bacterium Helicobacter pylori in their stomach mucosa.
In the pursuit of improving patient care, the continued development of POC testing can help support future demand for rapid diagnosis and treatment, with opportunities to implement successful POC facilities expanding over the years as the technology has improved.
Work allows genomic monitoring for epidemic strains of Vibrio cholerae bacteria The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the (..)
Ella, 28, was diagnosed with cystic fibrosis – a rare genetic disease which causes a build-up of thick, sticky mucus in the lungs, digestive tract, and sinuses – at 18 months old. Then, in 2018, Ella developed an infection that would not respond to treatment and was told her lung transplant was her only option. I was really sick.
Canadian clinical-stage biotech company Symvivo Corporation has developed an oral COVID-19 vaccine that entered clinical trials this week. The bacterium then secretes pDNA-protein complexes, triggering an immune response to treat and prevent infection associated with the delivered genes.
Previous genetic studies identified the pathogen that causes plague, including the Black Death of 1348, which killed more than one-third of Europe’s population, and the Great Plague of 1665. Growth rates for both epidemics are more consistent with bubonic plague, which is transmitted by bites of infected fleas, the researchers said.
Study will influence the global elimination strategy for yaws Genome sequencing has shed light on the re-emergence of the bacterium that causes yaws, a neglected tropical disease of the skin, bones and joints. The re-emergence followed a mass drug administration (MDA) campaign that aimed to eliminate the disease in Papua New Guinea.
It is believed to be involved in the development of chronic inflammatory intestinal diseases, to trigger diabetes, to be responsible for obesity, even neurological diseases such as multiple sclerosis and Parkinson’s could have their causes here – not to mention depressions and autistic disorders.
Interim results of the trial show that all participants developed an antibody response after two doses of the COVID-19 adjuvanted vaccine candidate. For example, CpG 1018 promotes development of the Th1 subset of helper T cells by targeting toll-like receptor 9 (TLR9). These are very promising results.
Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis. This can lead to acute infection, and a person could develop sepsis that requires immediate treatment.
Focusing on biologics, vaccine development and policy platforms in anticipation of an eventual outbreak is why we’re where we are today in terms of the positive side [of the pandemic].”. Most antibody drugs and vaccines have been developed to target parts of the spike protein. Pandemic Efforts.
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