XTalks

NOVEMBER 6, 2020

DNA vaccines designed using the platform consist of a combination of an advanced gene expression plasmid (pDNA) with gene(s) of interest, and a probiotic bacterium to deliver the vaccine directly to the gut, where it binds to intestinal epithelial cells.

Clinical Trials 75

Clinical Trials Clinical Trials Vaccination Vaccine 75

The Pharma Data

JULY 11, 2021

On the other hand, they can inhibit specific enzymes that regulate the accessibility to the genetic material and thus the gene expression in the T cells. On the one hand, they can boost the metabolism of T cells by inducing central regulators of energy metabolism. In doing so, they induce epigenetic changes.

Bacteria 52

Bacteria Genetics Scientist Regulation 52

The Pharma Data

JUNE 14, 2023

Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

RNA 40

RNA Regulation Scientist Bacteria 40

XTalks

DECEMBER 24, 2020

When a virus infects bacteria (these viruses are called bacteriophages), parts of its genetic material can get incorporated into the genome of the bacterium as sequences called clustered regularly interspaced short palindromic repeats (CRISPR).

Life Science 111

Life Science Vaccination Vaccine Gene 111