Drug Discovery World

JUNE 5, 2024

million to fund a new two-year collaborative partnership with King’s College London (KCL) to validate a portfolio of human genetic driven therapeutic targets for motor neuron disease (MND). Historical pipeline data suggests that drug targets with human genetic disease association are twice as likely to lead to approved drugs.

Research 69

Research Bioinformatics Drugs Genetics 69

Drug Discovery World

JULY 11, 2023

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. One system that has been especially useful in generating relevant and accurate biological data is the patient- derived xenograft (PDX) model for cancer studies.

Big Data 40

Big Data Development Life Science Drugs 40

Drug Discovery World

SEPTEMBER 6, 2022

DDW Editor Reece Armstrong looks at the cell and gene therapy landscape, examining the challenges facing developers and the trends we can expect to see throughout the year. . There’s no doubt that cell and gene therapies present some of the most exciting opportunities for emerging drugs. million price point per dose.

Gene Therapy 52

Gene Therapy Gene Manufacturing Medicine 52

Drug Discovery World

JULY 17, 2024

A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). The specific gene is called RNU4-2. The study estimates that these specific changes in the RNU4-2 gene can explain 0.4%

Genetics 52

Genetics Genome Project Genome Genomics 52

XTalks

APRIL 5, 2021

The Human Genome Project could not have succeeded without the use of bioinformatics. Since the conclusion of the project in 2003, bioinformatics tools have been used to identify genes and elucidate their function with the aim of developing gene-based strategies for disease prevention, diagnosis and treatment.

Bioinformatics 59

Bioinformatics Engineer Scientist Genome 59

Drug Discovery World

FEBRUARY 6, 2024

Researchers from the University of Oslo, University of Chicago Pritzker School of Medicine, and Insilico Medicine used an AI target discovery engine to analyse transcriptomic data to identify dual targets for cancer and ageing 5. The company’s platform evaluated more than 11.4

Marketing 69

Marketing Medicine Genome Genomics 69

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52