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Big data – charting a new path to drug discovery and development

Drug Discovery World

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. One system that has been especially useful in generating relevant and accurate biological data is the patient- derived xenograft (PDX) model for cancer studies.

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The challenges and trends of cell & gene therapies 

Drug Discovery World

DDW Editor Reece Armstrong looks at the cell and gene therapy landscape, examining the challenges facing developers and the trends we can expect to see throughout the year. . There’s no doubt that cell and gene therapies present some of the most exciting opportunities for emerging drugs. million price point per dose.

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Meet the Researcher: Nicola McCarthy, Milner Therapeutics Institute

Drug Discovery World

Then in the dry labs, which is headed up by a bioinformatician, we’re looking at big datasets – patient derived RNA seq data sets, for example – to see whether they can be mined to try and identify new potential targets. NM: I think probably it’s big data.

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Vodcast: Nicola McCarthy, Milner Therapeutics Institute, at SLAS 2024

Drug Discovery World

Then in the dry labs, which is headed up by a bioinformatician, we’re looking at big datasets – patient derived RNA seq data sets, for example – to see whether they can be mined to try and identify new potential targets. NM: I think probably it’s big data.

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Researchers discover genetic cause of neurodevelopment disorders

Drug Discovery World

A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). The specific gene is called RNU4-2. This discovery was initially made using data from the 100,000 Genomes Project, a study led by Genomics England and NHS England.

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How big data analytics can make personalised care a reality

Drug Discovery World

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care. Figure 2: Advanced data visualisation examples for transcriptomics data.