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Big data – charting a new path to drug discovery and development

Drug Discovery World

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. The post Big data – charting a new path to drug discovery and development appeared first on Drug Discovery World (DDW).

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Meet the Researcher: Nicola McCarthy, Milner Therapeutics Institute

Drug Discovery World

Then in the dry labs, which is headed up by a bioinformatician, we’re looking at big datasets – patient derived RNA seq data sets, for example – to see whether they can be mined to try and identify new potential targets. NM: I think probably it’s big data.

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Vodcast: Nicola McCarthy, Milner Therapeutics Institute, at SLAS 2024

Drug Discovery World

Then in the dry labs, which is headed up by a bioinformatician, we’re looking at big datasets – patient derived RNA seq data sets, for example – to see whether they can be mined to try and identify new potential targets. NM: I think probably it’s big data.

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How big data analytics can make personalised care a reality

Drug Discovery World

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care. Figure 2: Advanced data visualisation examples for transcriptomics data.

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Researchers discover genetic cause of neurodevelopment disorders

Drug Discovery World

While nearly all genes known to be involved in NDD are responsible for making proteins, RNU4-2 is not; instead, it makes an RNA molecule that plays an important role in how other genes are processed in cells. This discovery was initially made using data from the 100,000 Genomes Project, a study led by Genomics England and NHS England.

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The challenges and trends of cell & gene therapies 

Drug Discovery World

The use of big data and AL to direct the best patient candidates for CGT and to provide the best understanding of efficacy and benefits.” – ? According to the ASGCT, the gene therapy pipeline increased 16% from Q1 2021 with 3,579 gene, cell, and RNA therapies in development from preclinical through pre-registration stages. .