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Using analytics and bioassays to de-risk your mRNA LNP drug development programme

Pharmaceutical Technology

The swift development and deployment of messenger-RNA (mRNA) vaccines against the SARS-CoV-2 virus during the COVID-19 crisis has catapulted the pharmaceuticals industry into a new paradigm. Another area where we tend to see problems is in encapsulation efficiency,” says Andrew Kondratowicz, Bioassay Team Lead, Precision NanoSystems.

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Analytical quality by design: Development of cell-based bioassays

Bio Pharma Dive

Care needs to be taken during analytical development to ensure methodologies firstly, reflect the MoA, and are also reproducible, accurate, and robust.

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Cell and Gene Therapy Bioassay – A Prerequisite for the ATMPs Development

Roots Analysis

Bioassay – A Prerequisite for the Cell and Gene Therapy Development. In fact, from year 2016 to 2020 more than 300 IND filing for cell and gene therapy product have been recorded, indicating that several developers and innovators are more attracted towards the cell and gene therapies.

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Toregem BioPharma and WuXi Biologics to partner for antibody development

Pharmaceutical Technology

Biotech start-up Toregem BioPharma has signed a memorandum of understanding (MoU) with WuXi Biologics to develop the monoclonal antibody, TRG035. Under the MoU, the companies will form a collaboration for the development of TRG035, which targets USAG-1 to treat congenital adentia.

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KBI Biopharma Completes Eurofins DiscoverX Products Specialized Bioassay Certification Program

BioTech 365

& … Continue reading →

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4th Gene Therapy Analytical Development Summit 2022

pharmaphorum

As the field strives to strike a delicate balance between safety and efficacy, in the context of increased regulatory scrutiny and safety challenges, attending the 4 th Annual Gene Therapy Analytical Development as an analytical scientist has never been so important. Download the full event guide to find out more.

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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

The issue, however, is developing an effective way of targeting them. . Understanding the mechanism of PPIs and developing methods to target aberrant ones has been a key strategy in drug development. The flat interface remains the primary challenge facing the development of PPI modulators.

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