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Using analytics and bioassays to de-risk your mRNA LNP drug development programme

Pharmaceutical Technology

Another area where we tend to see problems is in encapsulation efficiency,” says Andrew Kondratowicz, Bioassay Team Lead, Precision NanoSystems. The bioassays are the canary in the coal mine of how well your process development is going. Outlook The era of mRNA-based genomic medicines is on the horizon. Where is your payload?

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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

It is a popular method in systems biology, requiring fewer compounds to be screened in bioassays, reducing time and cost. According to a 2021 publication “…recent advancements have made it possible to generate and analyse genome-wide PP I networks en masse by coupling Y2H with next-generation sequencing technology (NGS)”. .

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4th Gene Therapy Analytical Development Summit 2022

pharmaphorum

This year’s summit returns in-person to Boston to reunite 300+ analytical experts in innovative biotech, pharma and academia to continue to develop resilient, long-lasting and robust analytical tools to enhance the safety, quality, and efficacy of gene therapy products.