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Using analytics and bioassays to de-risk your mRNA LNP drug development programme

Pharmaceutical Technology

The swift development and deployment of messenger-RNA (mRNA) vaccines against the SARS-CoV-2 virus during the COVID-19 crisis has catapulted the pharmaceuticals industry into a new paradigm. Used in the COVID-19 vaccines, LNPs have shown a promising track record of protecting the mRNA cargo from degradation. Where is your payload?

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Let's Quit Sugar With Audiobook – Let's Quit Sugar

The Pharma Data

Aspartame bioassay findings portend human cancer hazards. Huang D, Dhawan T, Young S, et al. Fructose impairs glucose-induced hepatic triglyceride synthesis. Lipids Health Dis. 2011;10:20 DOI: 10.1186/1476-511X-10-20 . Huff J, LaDou J. Int J Occup Environ Health. 2007 OctDec;13(4):446-8. DOI: 10.1179/oeh.2007.13.4.446 2007.13.4.446 .

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