Remove Bioavailability Remove Containment Remove Marketing
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A winning combination: The benefits of micronization and containment in a single installation

Pharmaceutical Technology

The number of high-potency drug approvals has increased over the last decade, driven by the increasing use of APIs (Active Pharmaceutical Ingredients) in the pipeline and among marketed drugs. Containment challenges and opportunities High containment facilities guard against exposure to extremely potent products and cross-contamination.

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Mitigating the risks of cross-contamination during Oral Solid Dose (OSD) manufacturing

Pharmaceutical Technology

There are a number of reasons why OSD forms dominate the market, not least because they are simple to administer, and it is easy to differentiate one OSD product from another. This heightens the risk of cross contamination, requiring effective containment solutions, especially when handling highly potent powders.

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Expert Insights: Development and Manufacture of Highly Potent Oral Liquids

XTalks

From a market perspective, the oral liquid segment is anticipated to grow at a compound annual growth rate (CAGR) of approximately 6.5% Best practices include the use of contained engineering solutions to safeguard drug product integrity and protect operators. Dosing flexibility is another prominent advantage provided by PDFs.

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PureTech Reveals New CBD Pill to Rival Jazz’s Epidiolex

XTalks

Clinical-stage biotech company PureTech Health has announced it has developed a new oral CBD therapeutic candidate with improved bioavailability and tolerability, which could expand use of the CBD prodrug in a wide range of indications and age groups. Epidiolex contains sesame seed oil, restricting its use for some individuals.

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Compliance to convenience: understanding the latest innovations in capsule formulation

Pharmaceutical Technology

Softgel capsules, containing a liquid, paste or emulsion active ingredient, are trusted and favoured by many patients. They also offer enhanced bioavailability, exact dosing and an extended shelf life. Softgels have now achieved strong recognition in the prescription, consumer health and supplements markets.

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EverGrain’s Line of Barley-Based Products Scores Upcycled Certification

XTalks

In terms of its nutritional profile, EverPro is high in bioavailable protein, low in carbohydrates, contains just half a gram of sugar per 100 grams and is free from cholesterol, dairy and soy. Both Bright Barley and EverGrain are tapping into the massive global barley market, which is estimated to reach $24.7

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Synthesis-to-Clinic®: integrating isotopic labeling and human ADME to reduce time to clinic

Pharmaceutical Technology

We asked them to explain how the company has integrated its isotopic labeling and human ADME testing services to help streamline the drug development process and accelerate the time it takes to get drugs to market. This has proved to be an extremely effective option for molecules where an understanding of absolute bioavailability is required.