Cell-penetrating peptides as a delivery system for oligonucleotides
Drug Discovery World
AUGUST 3, 2022
Oligonucleotides act on the RNA level through different molecular pathways, but there is a major drawback when using them as drugs: their poor bioavailability and cellular uptake. When using a CPP as a delivery system, it must first be conjugated to its cargo molecule and internalised through endocytosis.
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