XTalks

MAY 23, 2024

For healthcare and life sciences industries, Skin Cancer Awareness Month helps highlight the importance of preventive measures and early detection. is a biotech and life sciences company dedicated to advancing the clinical development of innovative and groundbreaking therapeutic assets.

Life Science 72

Life Science Dermatology Drug Delivery Systems Medicine 72

XTalks

APRIL 11, 2023

By avoiding the stomach entirely, there is increased bioavailability and more sustained relief from symptoms. Switching to an infusion can overcome the disadvantages of the oral treatment, such as low gastrointestinal absorption and narrow therapeutic window.

Bioavailability 98

Bioavailability Genetics Nurses Development 98

XTalks

FEBRUARY 3, 2023

Unlike fulvestrant, elacestrant is not only orally bioavailable, but it has also demonstrated longer steady-states and works as a better combination partner with inhibitor agents like CDK4/6. Elacestrant had previously shown significant anti-estrogenic activity and potent anti-tumor activity in xenograft models.

Clinical Trials 97

Clinical Trials Clinical Trials FDA Approval Trials 97

XTalks

JUNE 14, 2023

Furthermore, the bioavailability of the active pharmaceutical ingredient (API) into the cornea is up to four times stronger with EyeSol technology. This innovative approach signifies a significant milestone in addressing the limitations of conventional eye care therapies.

Gene Silencing 97

Gene Silencing Drug Delivery FDA Approval RNA 97

XTalks

OCTOBER 2, 2024

With positive outcomes in preclinical models, EB-003 has confirmed oral bioavailability, adding to its therapeutic potential. Enveric is set to file an Investigational New Drug (IND) application by the third quarter of 2025, with plans to start clinical development by the end of the year.

Research 52

Research Bioavailability Trials Hormones 52

XTalks

AUGUST 8, 2024

Despite their potential, oligonucleotides present challenges in bioavailability due to their large, hydrophobic and negatively charged nature. Oligonucleotides such as antisense and small-interfering RNAs, are crafted using advanced chemical processes. They act by modifying protein expression, offering new treatments for rare diseases.

Development 64

Development Medicine Antibody Protein 64

XTalks

AUGUST 30, 2022

A major obstacle for CNS drug developers is the inability to target therapies to the CNS broadly (for instance, a therapy that is orally bioavailable as a pill and has difficulty crossing the blood-brain barrier) and certain CNS regions more specifically. The patients are waiting! Modern-Day Applications of Direct CNS Administration.

Trials 83

Trials Drug Delivery Drugs Gene 83

XTalks

SEPTEMBER 24, 2024

They are exploring a prodrug formulation of ganaxolone to potentially enhance the patient experience and treatment effectiveness by aiming to improve the drug’s bioavailability. This pursuit of improvement leads Marinus to investigate various aspects of ganaxolone’s potential.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Development 52

XTalks

SEPTEMBER 19, 2024

It was engineered to have high potency, bioavailability and kinase selectivity that led to improved efficacy and safety in B-cell malignancies. Zanubrutinib was specifically designed to improve outcomes and be successful where first- and second-generation BTK inhibitors were not.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Clinical Research 52

The Pharma Data

JANUARY 27, 2021

As a bioscience accelerator at the leading-edge of the life science industry, XPhyto targets growth through commercialization of its product pipeline and focused investment in impact driven innovation with the potential for meaningful value creation. . VANCOUVER, BC / ACCESSWIRE / January 28, 2021 / XPhyto Therapeutics Corp.

Drugs 52

Drugs Manufacturing Drug Delivery Production 52

Roots Analysis

JANUARY 28, 2024

She holds a bachelor’s degree in pharmaceutical sciences from a prestigious institute, which has provided her with a strong academic background. With her commitment to staying at the forefront of the healthcare and life sciences domain, she is able to effectively analyze complex datasets and provide actionable insights.

Big Data 40

Big Data Medicine Marketing Clinical Trials 40

XTalks

MARCH 24, 2025

Without effective disease-modifying therapies and optimal management strategies, the constant fatigue, swelling and mental health challenges surrounding those living with C3G profoundly disrupt daily life and overall quality of life.

Bioavailability 71

Bioavailability Immune Response Protein Bacteria 71