XTalks

DECEMBER 5, 2022

Clinical-stage biotech company PureTech Health has announced it has developed a new oral CBD therapeutic candidate with improved bioavailability and tolerability, which could expand use of the CBD prodrug in a wide range of indications and age groups. Jazz bought out Epidiolex developer GW Pharmaceuticals for the drug in a whopping $7.2

Bioavailability 97

Bioavailability FDA Approval Trials Drugs 97

Camargo

DECEMBER 22, 2021

In addition, the size and complexity of a development program can vary significantly depending on product characteristics, market dynamics, and regulatory pathway. Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence.

Bioequivalency 169

Bioequivalency Production Genotoxicity In-Vivo 169

XTalks

JUNE 27, 2024

Therefore, techniques and technologies that promote drug solubility and bioavailability are in high demand. Kinetisol™ Technology represents a significant leap in amorphous solid dispersion development and manufacturing. This method is environmentally sustainable and fast, taking seconds instead of hours or days.

Bioavailability 59

Bioavailability Manufacturing Drugs Development 59

Pharmaceutical Technology

AUGUST 3, 2022

Yet commercialising a drug is no easy journey, hence why just 10% of new drug candidates succeed in making it to market. During this stage, a team of lab technicians must identify the best way to manufacture the active pharmaceutical ingredient (API) into a suitable dosage form for pilot production.

Development 130

Development Production Manufacturing Bioavailability 130

Pharmaceutical Technology

JUNE 14, 2023

The number of high-potency drug approvals has increased over the last decade, driven by the increasing use of APIs (Active Pharmaceutical Ingredients) in the pipeline and among marketed drugs. Furthermore, the number of marketed high potency APIs (HPAPIs) tends to increase over time as more HPAPIs in development gain approval.

Containment 130

Containment Manufacturing Contract Manufacturing Bioavailability 130

Pharmaceutical Technology

APRIL 12, 2023

Evidence suggests that API manufacturing is gaining in complexity, as well as sophistication, and therefore adding to the risk profile of drug development. The ingredients used in these drugs are high potency, even at small doses, and pose a risk to both human health and cross-contamination with other drugs in a manufacturing environment.

Manufacturing 130

Manufacturing Production Containment Contamination 130

Cloudbyz

MARCH 5, 2024

Manufacturing Process : Small Molecules: Manufactured through chemical synthesis, small molecule drugs can be consistently reproduced with a high degree of purity and stability. The conditions affecting the living system can influence the final product, making the manufacturing process more sensitive and challenging.

Development 97

Development Drugs Immune Response Manufacturing 97

FDA Law Blog

JULY 23, 2024

Design validation may be covered by clinical studies, pharmacokinetic/pharmacodynamic or bioequivalence/bioavailability studies, literature, simulated bench testing, and/or anthropometric data and should include endpoints that have the capability of validating device performance.

Drug Delivery 105

Drug Delivery Drugs Bioequivalency Production 105

XTalks

FEBRUARY 25, 2022

The first-of-its-kind certification , which launched last year, allows food and beverage manufacturers that use upcycled ingredients to place the claim on their packaging. Both Bright Barley and EverGrain are tapping into the massive global barley market, which is estimated to reach $24.7 EverGrain’s UFA Certification.

Production 98

Production Protein Branding Bioavailability 98

The Pharma Data

JANUARY 7, 2021

Emerging Technology Needs and Value Proposition for Strategic Partnerships with Contract Development and Manufacturing Organizations (CDMOs). The pharmaceutical product landscape is rapidly and fundamentally changing with profound impact on research and development strategy and technology needs.

Bioavailability 52

Bioavailability Production Manufacturing Drugs 52

Pharmaceutical Technology

JANUARY 25, 2023

According to a whitepaper from contract research, development and manufacturing organisation Syngene, PROTACs are effective against “undruggable” targets such as transcription factors, and scaffolding proteins that cannot be otherwise targeted by the traditional small molecule inhibitors.

Protein 130

Protein Bioavailability Development Scientist 130

Pharmaceutical Technology

MARCH 21, 2023

Considering renewed interest and high demand of CBD, Frewitt, an innovative manufacturer of premium-quality mills and a world leader in powder size reduction technologies, recently conducted tests in partnership with Cannawyss to ascertain the best milling methods and equipment for CBD crystals. [i]

Production 243

Production Bioavailability Pharmacy Clinical Trials 243

Roots Analysis

MARCH 2, 2022

However, it is important to highlight that there are still several challenges which need to be addressed in order to develop biologic drugs capable of effectively being administered via the oral route without undergoing significant losses in specificity and / or bioavailability. Oral Proteins and Peptides Market (4th Edition).

Protein 52

Protein Drugs Drug Delivery Drug Delivery Systems 52

Roots Analysis

MARCH 1, 2022

This can be attributed to ease of delivery, increased bioavailability and by-pass of first-pass metabolism offered by this type of route of administration. The intranasal therapeutics and drug delivery systems market is anticipated to grow significantly, during 2022-2035. Intranasal Therapeutics and Drug Delivery Systems.

Drug Delivery Systems 52

Drug Delivery Systems Drug Delivery Drugs Bioavailability 52

The Pharma Data

JANUARY 27, 2021

Construction of commercial drug manufacturing facility in Germany. Development of oral biosensor and contract development & manufacturing. Vektor will position itself for commercial manufacturing, pipeline development and drug formulations for critical mental health conditions.

Drugs 52

Drugs Manufacturing Drug Delivery Production 52

The Pharma Data

JANUARY 3, 2021

1 Good Manufacturing Practice. The information in the press release is information that Nanoform is obliged to make public pursuant to the EU Market Abuse Regulation. Nanoform’s shares are listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki (ticker: NANOFH) and Stockholm (ticker: NANOFS).

Containment 40

Containment Bioavailability Clinical Trials Clinical Trials 40

Roots Analysis

JANUARY 28, 2024

Conclusion Owing to the increasing popularity of big data in healthcare domain, there is a huge impact of big data in healthcare market size. Throughout her career, Jayita has contributed to over six syndicate market research reports, covering a wide range of trending domains.

Big Data 40

Big Data Medicine Marketing Clinical Trials 40

Camargo

SEPTEMBER 30, 2021

The drug development process can be broken down into three main disciplines: chemistry, manufacturing, and control (CMC); nonclinical; and clinical. CMC programs include drug substance manufacturing process scale-up, stability testing, early formulation development, and, later on, manufacturing process validation, among other considerations.

Development 201

Development Research Manufacturing In-Vivo 201

XTalks

NOVEMBER 6, 2024

per share, the offering included 1,300,000 ordinary shares, which began trading on the Nasdaq Global Market under the ticker symbol GELS on October 29, 2024. The stable gel matrix holds multiple ingredients, offering targeted release and enhanced bioavailability while optimizing patient experience. Priced at $4.0

Drug Delivery 104

Drug Delivery Drugs Bioequivalency Bioavailability 104

Roots Analysis

FEBRUARY 20, 2022

In fact, it has been observed that around 40% of the pharmaceutical products approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the prime reasons that leads to failure in obtaining approval authorization.

Contract Manufacturing 52

Contract Manufacturing Bioavailability Manufacturing Drug Delivery Systems 52

Roots Analysis

MARCH 13, 2022

Given the evident benefits of biologics over small molecule drugs (including high efficacy, target specificity and favorable safety profiles), the biopharmaceutical market is poised to witness continued and consistent growth over the next several years. As a result, the demand for biopharmaceutical excipients has grown considerably.

Manufacturing 52

Manufacturing Drug Delivery Marketing Drug Delivery Systems 52

Pharmaceutical Technology

MARCH 7, 2023

Due to rising healthcare spending, launch of novel treatments, and the rise of chronic diseases in an aging population, the global pharmaceutical packaging equipment market is rapidly expanding. Recent analysis valued the market [i] at USD 8.5 billion in 2021, which is expected to reach $15.77

Production 130

Production Containment Bioavailability Manufacturing 130

Roots Analysis

OCTOBER 2, 2023

Additionally, it increases the bioavailability and solubility of the attached molecule. In fact, in the last twenty years, the United States Food and Drug Administration (USFDA) and the European Medicines Agency (EMA) have authorized the market approval of around 80 nanomedicines.

Drug Delivery 40

Drug Delivery Drugs Bioavailability Development 40

The Pharma Data

MAY 14, 2021

Plus considering that it takes our manufacturing facility 3 whole months to source and produce just a single batch of ProstaStream and that each capsule contains the purest and most bioavailable form of these prostate-supporting power foods in existence…. Any likeness to a real Frank Neal living or dead is entirely coincidental.

Packaging 52

Packaging Packaging Production Bioavailability 52

Roots Analysis

MAY 21, 2024

In fact, it has been observed that around 40% of the pharmaceutical drugs approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the main causes of drug failure in obtaining approval authorization.

Drug Delivery 40

Drug Delivery Drugs Gene Therapy Bioavailability 40