Pharmaceutical Technology

MAY 31, 2023

It is expected to accelerate the development of CFT8919 in important international markets. CFT8919 is an orally bioavailable BiDAC degrader designed to exhibit potent and selective activity against EGFR L858R in patients with non-small cell lung cancer (NSCLC).

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XTalks

FEBRUARY 5, 2025

The HALO platform enhances peptide half-life, facilitating monthly dosing and titration-free regimens, while the MOMENTUM platform optimizes oral bioavailability. Related: New Zepbound TV Commercial Inspires ‘Change’ The Obesity and Weight-Loss Drug Market So Far The global anti-obesity drugs market is set to grow from $6.15

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Hormones Bioavailability Clinical Trials Clinical Trials 59

XTalks

DECEMBER 5, 2022

Clinical-stage biotech company PureTech Health has announced it has developed a new oral CBD therapeutic candidate with improved bioavailability and tolerability, which could expand use of the CBD prodrug in a wide range of indications and age groups. Last year, Pfizer struck a $6.7

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Pharmaceutical Technology

SEPTEMBER 23, 2022

While Restasis and Xiidra have been in use in the US market for a long time, both treatments have been associated with patient satisfaction issues such as a non-favorable tolerability profile and a slow onset of action. This gap in the market is what the late-stage pipeline therapies are currently targeting. Novaliq’s CyclASol (0.1%

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Camargo

DECEMBER 22, 2021

In addition, the size and complexity of a development program can vary significantly depending on product characteristics, market dynamics, and regulatory pathway. Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence.

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Pharmaceutical Technology

NOVEMBER 24, 2022

We asked them to explain how the company has integrated its isotopic labeling and human ADME testing services to help streamline the drug development process and accelerate the time it takes to get drugs to market. This has proved to be an extremely effective option for molecules where an understanding of absolute bioavailability is required.

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Bioavailability Manufacturing Drugs Production 130

XTalks

JANUARY 30, 2025

From a market perspective, the oral liquid segment is anticipated to grow at a compound annual growth rate (CAGR) of approximately 6.5% Improved bioavailability can lead to a faster onset of therapeutic effects, which is especially valuable in conditions where prompt action is required.

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FDA Law Blog

JULY 23, 2024

Design validation may be covered by clinical studies, pharmacokinetic/pharmacodynamic or bioequivalence/bioavailability studies, literature, simulated bench testing, and/or anthropometric data and should include endpoints that have the capability of validating device performance.

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Drug Delivery Drugs Bioequivalency Production 105

XTalks

JUNE 27, 2024

Therefore, techniques and technologies that promote drug solubility and bioavailability are in high demand. Their focus is on improving drug solubility and bioavailability with powerful amorphous dispersion technologies, such as KinetiSol for poorly soluble compounds.

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Bioavailability Manufacturing Drugs Development 59

Pharmaceutical Technology

AUGUST 22, 2022

They also offer enhanced bioavailability, exact dosing and an extended shelf life. Softgels have now achieved strong recognition in the prescription, consumer health and supplements markets. Compared to traditional hard capsules or granules, they are easier to swallow and more attractive in appearance.

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Pharmaceutical Technology

DECEMBER 19, 2022

This is achieved with a reduced beads load, and a higher energy efficiency compared to competing bead mill equipment on the market. Additionally, the NanoWitt technology allows API milling down to a final product size of 50nm in diameter in a single operation with a minimal temperature increase. Measuring particle size and characterisation.

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XTalks

FEBRUARY 25, 2022

In terms of its nutritional profile, EverPro is high in bioavailable protein, low in carbohydrates, contains just half a gram of sugar per 100 grams and is free from cholesterol, dairy and soy. Both Bright Barley and EverGrain are tapping into the massive global barley market, which is estimated to reach $24.7

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Production Protein Branding Bioavailability 98

Delveinsight

FEBRUARY 16, 2021

Numerous immunotherapy-based combinations are already trying in the old game of gleek to stake up some share in previously untreated, metastatic kidney cancer; however, the market seems to expand as the new entrants continue to make their entry. Takeda wins big in cytomegalovirus infection market.

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Pharmaceutical Technology

JUNE 14, 2023

The number of high-potency drug approvals has increased over the last decade, driven by the increasing use of APIs (Active Pharmaceutical Ingredients) in the pipeline and among marketed drugs. Furthermore, the number of marketed high potency APIs (HPAPIs) tends to increase over time as more HPAPIs in development gain approval.

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Containment Manufacturing Contract Manufacturing Bioavailability 130

Delveinsight

SEPTEMBER 8, 2021

As per DelveInsight’s report on Benlysta (Belimumab) market forecast , the sale of Belimumab has kept on increasing year after year. Currently, the SLE therapeutics market is revolving around only one drug i.e It is the top-selling medication in the market. Anifrolumab (MEDI-546). Baricitinib (INCB-028050).

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The Pharma Data

JANUARY 7, 2021

While oral delivery route (62%) is still the most prevalent amongst marketed drug products, alternative adminstrations such as injection (22%), cutaneous, mucosal, inhalation, and others are making up a greater percentage as the industry works to improve bioavailability and subsequent efficacy.

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Bioavailability Production Manufacturing Drugs 52

Pharmaceutical Technology

FEBRUARY 3, 2023

There are a number of reasons why OSD forms dominate the market, not least because they are simple to administer, and it is easy to differentiate one OSD product from another. Effective supply chain management is essential for OSD manufacturers that are operating in such a competitive market.

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Pharmaceutical Technology

AUGUST 3, 2022

Yet commercialising a drug is no easy journey, hence why just 10% of new drug candidates succeed in making it to market. Milling is a central part of powder processing, as this is where coarse particles are broken down into smaller ones for a variety of processability, bioavailability, reactivity, and safety-related reasons.

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Pharmaceutical Technology

OCTOBER 25, 2022

As the number of FDC products in development and coming to the market increase, the pharmaceutical industry is looking to FDCs as a promising strategy to repurpose, repackage, and expand indications for existing and novel therapeutic agents. Accelerated regulatory pathway. To find out more, download the whitepaper below.

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pharmaphorum

FEBRUARY 25, 2021

The current marketing application for the drug in the US is for two-weekly dosing, but Chiesi and Protalix hope that can be extended once the full BRIGHT dataset is in. PRX-102 would compete against Fabrazyme and Amicus Therapeutics’ Galafold (migalastat) if approved by the FDA, as Takeda does not sell Replagal in the US market.

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Drugs Bioavailability Antibody Marketing 80

Pharmaceutical Technology

JANUARY 25, 2023

According to Atul Tiwari , Head-Discovery Service Solutions at Syngene “Realising the scientific and market potential of this area, we made proactive and early efforts to establish new models, platforms, identifying new ligases, ligands and establishing the ADME-PK correlations of the PROTACs.

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Pharmaceutical Technology

MARCH 21, 2023

Visit our privacy policy for more information about our services, how we may use, process and share your personal data, including information on your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Please check your email to download the Whitepaper.

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Cloudbyz

MARCH 5, 2024

Oral Bioavailability: Developing small molecules that are effectively absorbed when administered orally, while also being stable in the digestive system, can be complex. Enhancing bioavailability is often a key focus in the development of small molecule drugs.

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Roots Analysis

MARCH 2, 2022

However, it is important to highlight that there are still several challenges which need to be addressed in order to develop biologic drugs capable of effectively being administered via the oral route without undergoing significant losses in specificity and / or bioavailability. Oral Proteins and Peptides Market (4th Edition).

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Protein Drugs Drug Delivery Drug Delivery Systems 52

pharmaphorum

JANUARY 16, 2023

The bi-weekly intramuscular shot – which was also approved in China in 2021 – will enter a crowded market for long-acing injectable (LAI) schizophrenia therapies in the US and have to take on heavyweight competition, including drugs that require less frequent dosing.

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FDA Approval Drugs Bioavailability Marketing 52

Roots Analysis

MARCH 1, 2022

This can be attributed to ease of delivery, increased bioavailability and by-pass of first-pass metabolism offered by this type of route of administration. The intranasal therapeutics and drug delivery systems market is anticipated to grow significantly, during 2022-2035. Intranasal Therapeutics and Drug Delivery Systems.

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Drug Delivery Systems Drug Delivery Drugs Bioavailability 52

Pharmaceutical Technology

APRIL 12, 2023

This new market focus shines a spotlight on small molecule API manufacturers and their capacity for handling innovative NME sponsor requirements as well as the value-add services and technical and regulatory expertise they can offer as strategic production partners. The sampling device is suitable for operation in a vacuum environment.

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Pharmaceutical Technology

JUNE 26, 2022

Understanding the polymorphism of a drug compound plays a key role in both drug substance and drug product development, because it can negatively impact the downstream stability, solubility, and bioavailability of a drug. Streamlined processes to reduce time to market for drugs. Integrated drug substance and drug product services.

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pharmaphorum

AUGUST 19, 2022

If all goes well, the aim is to bring resiniferatoxin to market in 2025. Among these still in development, Glenmark’s orally active GRC17536 cleared a phase 2a study in diabetic neuropathy but has bioavailability issues that have held up a phase 3 programme.

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Drugs Bioavailability Trials Clinical Development 52

Delveinsight

JULY 30, 2020

The global Adrenoleukodystrophy market size for the forecast period 2020-30, which was estimated to be USD 922.43 In patients with CALD, Adrenoleukodystrophy market offers two therapies, namely Lorenzo’s oil and haematopoietic stem cell transplantation (HSCT) , using either umbilical cord stem cells or bone marrow stem cells.

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Hormones Marketing Gene Trials 52

The Pharma Data

JULY 12, 2021

Molnupiravir (EIDD-2801/MK-4482) is an investigational, orally bioavailable form of a potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. For further information regarding our clinical trials, please visit [link] or [link]. About Molnupiravir.

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Clinical Trials Clinical Trials Bioavailability Trials 52

Roots Analysis

SEPTEMBER 1, 2023

By charting new waters and creating uncontested market spaces, companies can differentiate themselves and unlock unprecedented growth opportunities. In this blog post, I’ll explore how pharma / biotech companies can leverage the blue ocean and red ocean strategy to make waves in the market.

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Drug Delivery Marketing Drug Delivery Systems Drugs 52

The Pharma Data

MARCH 8, 2021

Molnupiravir (EIDD-2801/MK-4482) is an investigational, orally-bioavailable form of a potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. About Molnupiravir. About Ridgeback Biotherapeutics.

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The Pharma Data

NOVEMBER 11, 2020

As an orally bioavailable small molecule with broad antiviral activity, SLV213 could be a valuable treatment to meet today’s urgent need to fight COVID-19 as well other life-threatening infectious diseases, such as Chagas disease, Ebola virus disease, and Nipah virus infection.”. For more information, visit www.selvarx.com.

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Protein Bioavailability Development Drugs 52

The Pharma Data

NOVEMBER 26, 2020

This novel nanoparticle formation technology provides hope for improving the possibilities and probabilities of developing better medicines for patients and it expands Nanoform’s reach into the growing biological market. Finnish time. About Nanoform. Certified Adviser: Danske Bank A/S, Finland Branch, +358 40 562 1806.

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Containment Medicine Development Bioavailability 52

Delveinsight

JANUARY 7, 2021

The startup recently raised USD 87 million to propel itself in a competitive market. The prospects of small molecule binders of RNA over current protein and RNA-based approaches cover potency, selectivity, oral bioavailability, tissue distribution, and central nervous system penetration. Terns raises USD 87 Million for NASH drugs.

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RNA Clinical Trials Clinical Trials Bioavailability 52

The Pharma Data

JANUARY 20, 2021

Part B is designed to be a confirmatory post-market approval observational trial to confirm long-term renal protection and assess the difference in kidney function between treated and placebo patients as measured by eGFR over a two-year period from the start of dosing of each patient. It also showed that Nefecon was generally well-tolerated.

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