Pharmaceutical Technology

MAY 31, 2023

It is expected to accelerate the development of CFT8919 in important international markets. CFT8919 is an orally bioavailable BiDAC degrader designed to exhibit potent and selective activity against EGFR L858R in patients with non-small cell lung cancer (NSCLC).

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In-Vivo Bioavailability In-Vitro Licensing 130

XTalks

FEBRUARY 5, 2025

The HALO platform enhances peptide half-life, facilitating monthly dosing and titration-free regimens, while the MOMENTUM platform optimizes oral bioavailability. Related: New Zepbound TV Commercial Inspires ‘Change’ The Obesity and Weight-Loss Drug Market So Far The global anti-obesity drugs market is set to grow from $6.15

Hormones 59

Hormones Bioavailability Clinical Trials Clinical Trials 59

XTalks

DECEMBER 5, 2022

Clinical-stage biotech company PureTech Health has announced it has developed a new oral CBD therapeutic candidate with improved bioavailability and tolerability, which could expand use of the CBD prodrug in a wide range of indications and age groups. Last year, Pfizer struck a $6.7

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Bioavailability FDA Approval Trials Drugs 97

Pharmaceutical Technology

SEPTEMBER 23, 2022

While Restasis and Xiidra have been in use in the US market for a long time, both treatments have been associated with patient satisfaction issues such as a non-favorable tolerability profile and a slow onset of action. This gap in the market is what the late-stage pipeline therapies are currently targeting. Novaliq’s CyclASol (0.1%

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Development Drugs Clinical Trials Clinical Trials 147

Camargo

DECEMBER 22, 2021

In addition, the size and complexity of a development program can vary significantly depending on product characteristics, market dynamics, and regulatory pathway. Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence.

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Bioequivalency Production Genotoxicity In-Vivo 169

XTalks

JANUARY 30, 2025

From a market perspective, the oral liquid segment is anticipated to grow at a compound annual growth rate (CAGR) of approximately 6.5% Improved bioavailability can lead to a faster onset of therapeutic effects, which is especially valuable in conditions where prompt action is required.

Manufacturing 52

Manufacturing Development Compliance Production 52

FDA Law Blog

JULY 23, 2024

Design validation may be covered by clinical studies, pharmacokinetic/pharmacodynamic or bioequivalence/bioavailability studies, literature, simulated bench testing, and/or anthropometric data and should include endpoints that have the capability of validating device performance.

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Drug Delivery Drugs Bioequivalency Production 105

XTalks

JUNE 27, 2024

Therefore, techniques and technologies that promote drug solubility and bioavailability are in high demand. Their focus is on improving drug solubility and bioavailability with powerful amorphous dispersion technologies, such as KinetiSol for poorly soluble compounds.

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Bioavailability Manufacturing Drugs Development 59

Pharmaceutical Technology

AUGUST 22, 2022

They also offer enhanced bioavailability, exact dosing and an extended shelf life. Softgels have now achieved strong recognition in the prescription, consumer health and supplements markets. Compared to traditional hard capsules or granules, they are easier to swallow and more attractive in appearance.

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Compliance Bioavailability Containment Branding 130

Roots Analysis

FEBRUARY 20, 2022

In fact, it has been observed that around 40% of the pharmaceutical products approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the prime reasons that leads to failure in obtaining approval authorization. Nanoparticles Contract Manufacturing. Web: [link].

Contract Manufacturing 52

Contract Manufacturing Bioavailability Manufacturing Drug Delivery Systems 52

XTalks

FEBRUARY 25, 2022

In terms of its nutritional profile, EverPro is high in bioavailable protein, low in carbohydrates, contains just half a gram of sugar per 100 grams and is free from cholesterol, dairy and soy. Both Bright Barley and EverGrain are tapping into the massive global barley market, which is estimated to reach $24.7

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Production Protein Branding Bioavailability 98

Delveinsight

FEBRUARY 16, 2021

Numerous immunotherapy-based combinations are already trying in the old game of gleek to stake up some share in previously untreated, metastatic kidney cancer; however, the market seems to expand as the new entrants continue to make their entry. Takeda wins big in cytomegalovirus infection market.

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Marketing Protein Bioavailability Drugs 52

pharmaphorum

MAY 5, 2021

However, Pfizer has a plan to get the franchise back on track, as it also faces the risk of a competitor reaching the market from Merck & Co. Another big seller – pneumococcal conjugate vaccine Prevnar 13 – was hit by COVID-19 disruptions that cut sales by 11% to $1.3 Feature image copyright BioNTech SE 2020, all rights reserved.

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Vaccination Vaccine Sales Bioavailability 105

The Pharma Data

JANUARY 7, 2021

While oral delivery route (62%) is still the most prevalent amongst marketed drug products, alternative adminstrations such as injection (22%), cutaneous, mucosal, inhalation, and others are making up a greater percentage as the industry works to improve bioavailability and subsequent efficacy.

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Bioavailability Production Manufacturing Drugs 52

Pharmaceutical Technology

AUGUST 3, 2022

Yet commercialising a drug is no easy journey, hence why just 10% of new drug candidates succeed in making it to market. Milling is a central part of powder processing, as this is where coarse particles are broken down into smaller ones for a variety of processability, bioavailability, reactivity, and safety-related reasons.

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Development Production Manufacturing Bioavailability 130

Pharmaceutical Technology

OCTOBER 25, 2022

As the number of FDC products in development and coming to the market increase, the pharmaceutical industry is looking to FDCs as a promising strategy to repurpose, repackage, and expand indications for existing and novel therapeutic agents. Accelerated regulatory pathway. To find out more, download the whitepaper below.

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The Pharma Data

DECEMBER 9, 2020

Artificial intelligence holds immense promise to catalyze the development of the next generation of highly selective, orally bioavailable molecules, with reduced side effects, for the most impactful drug targets,” Feinberg said at the time of the launch.

Marketing 52

Marketing In-Vivo Protein In-Vitro 52

pharmaphorum

FEBRUARY 25, 2021

The current marketing application for the drug in the US is for two-weekly dosing, but Chiesi and Protalix hope that can be extended once the full BRIGHT dataset is in. PRX-102 would compete against Fabrazyme and Amicus Therapeutics’ Galafold (migalastat) if approved by the FDA, as Takeda does not sell Replagal in the US market.

Drugs 80

Drugs Bioavailability Antibody Marketing 80

Pharmaceutical Technology

JANUARY 25, 2023

According to Atul Tiwari , Head-Discovery Service Solutions at Syngene “Realising the scientific and market potential of this area, we made proactive and early efforts to establish new models, platforms, identifying new ligases, ligands and establishing the ADME-PK correlations of the PROTACs.

Protein 130

Protein Bioavailability Development Scientist 130

Cloudbyz

MARCH 5, 2024

Oral Bioavailability: Developing small molecules that are effectively absorbed when administered orally, while also being stable in the digestive system, can be complex. Enhancing bioavailability is often a key focus in the development of small molecule drugs.

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Development Drugs Immune Response Manufacturing 97

The Pharma Data

DECEMBER 3, 2020

SOL-578 is a best-in-class checkpoint kinase 1 (Chk1) inhibitor featuring high kinase selectivity and oral bioavailability which targets the DNA Damage Response (DDR) network. The company’s mission is to increase survival and improve outcomes for cancer patients with CNS tumors. ” About SOL-578. About PharmaEngine (TWO: 4162).

Licensing 52

Licensing Licensing Bioavailability DNA 52

Roots Analysis

MARCH 2, 2022

However, it is important to highlight that there are still several challenges which need to be addressed in order to develop biologic drugs capable of effectively being administered via the oral route without undergoing significant losses in specificity and / or bioavailability. Oral Proteins and Peptides Market (4th Edition).

Protein 52

Protein Drugs Drug Delivery Drug Delivery Systems 52

pharmaphorum

JANUARY 16, 2023

The bi-weekly intramuscular shot – which was also approved in China in 2021 – will enter a crowded market for long-acing injectable (LAI) schizophrenia therapies in the US and have to take on heavyweight competition, including drugs that require less frequent dosing.

FDA Approval 52

FDA Approval Drugs Bioavailability Marketing 52

Roots Analysis

MARCH 1, 2022

This can be attributed to ease of delivery, increased bioavailability and by-pass of first-pass metabolism offered by this type of route of administration. The intranasal therapeutics and drug delivery systems market is anticipated to grow significantly, during 2022-2035. Intranasal Therapeutics and Drug Delivery Systems.

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Drug Delivery Systems Drug Delivery Drugs Bioavailability 52

XTalks

FEBRUARY 3, 2023

Stemline Therapeutics, a commercial-stage biopharmaceutical company focused on the development and commercialization of novel oncology therapeutics and a wholly owned subsidiary of the Menarini Group, will market Orserdu in the US. ER+, HER2- Breast Cancer ER+, HER2- cancers account for about 75 percent of breast cancers.

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Clinical Trials Clinical Trials FDA Approval Trials 97

Roots Analysis

MARCH 13, 2022

Given the evident benefits of biologics over small molecule drugs (including high efficacy, target specificity and favorable safety profiles), the biopharmaceutical market is poised to witness continued and consistent growth over the next several years. Future Evolution of Biopharmaceutical Excipient Manufacturing Market. Web: [link].

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Manufacturing Drug Delivery Marketing Drug Delivery Systems 52

Roots Analysis

MAY 21, 2024

In fact, it has been observed that around 40% of the pharmaceutical drugs approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the main causes of drug failure in obtaining approval authorization.

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Drug Delivery Drugs Gene Therapy Bioavailability 40

Pharmaceutical Technology

JUNE 26, 2022

Understanding the polymorphism of a drug compound plays a key role in both drug substance and drug product development, because it can negatively impact the downstream stability, solubility, and bioavailability of a drug. Streamlined processes to reduce time to market for drugs. Integrated drug substance and drug product services.

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Manufacturing Drugs Production Development 130

pharmaphorum

AUGUST 19, 2022

If all goes well, the aim is to bring resiniferatoxin to market in 2025. Among these still in development, Glenmark’s orally active GRC17536 cleared a phase 2a study in diabetic neuropathy but has bioavailability issues that have held up a phase 3 programme.

Drugs 52

Drugs Bioavailability Trials Clinical Development 52

Delveinsight

JULY 30, 2020

The global Adrenoleukodystrophy market size for the forecast period 2020-30, which was estimated to be USD 922.43 In patients with CALD, Adrenoleukodystrophy market offers two therapies, namely Lorenzo’s oil and haematopoietic stem cell transplantation (HSCT) , using either umbilical cord stem cells or bone marrow stem cells.

Hormones 52

Hormones Marketing Gene Trials 52

Roots Analysis

SEPTEMBER 1, 2023

By charting new waters and creating uncontested market spaces, companies can differentiate themselves and unlock unprecedented growth opportunities. In this blog post, I’ll explore how pharma / biotech companies can leverage the blue ocean and red ocean strategy to make waves in the market.

Drug Delivery 52

Drug Delivery Marketing Drug Delivery Systems Drugs 52

Roots Analysis

OCTOBER 2, 2023

Additionally, it increases the bioavailability and solubility of the attached molecule. In fact, in the last twenty years, the United States Food and Drug Administration (USFDA) and the European Medicines Agency (EMA) have authorized the market approval of around 80 nanomedicines.

Drug Delivery 40

Drug Delivery Drugs Bioavailability Development 40

The Pharma Data

NOVEMBER 11, 2020

As an orally bioavailable small molecule with broad antiviral activity, SLV213 could be a valuable treatment to meet today’s urgent need to fight COVID-19 as well other life-threatening infectious diseases, such as Chagas disease, Ebola virus disease, and Nipah virus infection.”. For more information, visit www.selvarx.com.

Protein 52

Protein Bioavailability Development Drugs 52

XTalks

MAY 23, 2024

There is an unmet medical need to bring to the market a non-invasive, cost effective and aesthetically acceptable treatment, which is also relatively painless and easily accessible in an outpatient setting. TDDS are advantageous due to their high bioavailability, low systemic toxicity and improved patient compliance.

Life Science 72

Life Science Dermatology Drug Delivery Systems Medicine 72

Delveinsight

JANUARY 7, 2021

The startup recently raised USD 87 million to propel itself in a competitive market. The prospects of small molecule binders of RNA over current protein and RNA-based approaches cover potency, selectivity, oral bioavailability, tissue distribution, and central nervous system penetration. Terns raises USD 87 Million for NASH drugs.

RNA 52

RNA Clinical Trials Clinical Trials Bioavailability 52

The Pharma Data

JANUARY 20, 2021

Part B is designed to be a confirmatory post-market approval observational trial to confirm long-term renal protection and assess the difference in kidney function between treated and placebo patients as measured by eGFR over a two-year period from the start of dosing of each patient. It also showed that Nefecon was generally well-tolerated.

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Trials Containment Clinical Trials Clinical Trials 52

Roots Analysis

JANUARY 28, 2024

Conclusion Owing to the increasing popularity of big data in healthcare domain, there is a huge impact of big data in healthcare market size. Throughout her career, Jayita has contributed to over six syndicate market research reports, covering a wide range of trending domains.

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Big Data Medicine Marketing Clinical Trials 40