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A major obstacle for CNS drug developers is the inability to target therapies to the CNS broadly (for instance, a therapy that is orally bioavailable as a pill and has difficulty crossing the blood-brain barrier) and certain CNS regions more specifically. All facilities (such as lab, pharmacy, MRI, etc.) The patients are waiting!
Challenges for micronization Micronization has become an increasingly significant process in the pharmaceutical industry and is necessary to produce APIs with better solubility and improved bioavailability. A number of high-impact milling methods, including ball, hammer, pin, and disc mills, have been adopted to meet this need.
and could change how “bioavailable” the all-important EBM triggering nutrients are. Bioavailable is a word that scientists use to describe how easy it is for your body to use a nutrient…. Now imagine that instead of having to hang your head in shame at the pharmacy…. Or explain your embarrassing symptoms to your urologist….
The paper concludes by noting that the potential cost reductions generated in the production of highly bioavailable APIs, as well as improved quality control, can ultimately promote production of custom formulations. Full details of the research by Fribourg University, including methods, results, and discussion, can be found here.
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