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How PK Modeling Can Inform Sample Size Estimation and Dose Selection for Your Product

Camargo

Given that it can take up to 20 years for a final product to be approved, it is unsurprising that drug attrition rates are very high. Pharmacokinetics (PK) and bioequivalence (BE) studies serve as the foundation of determining the fate of drug products. Pharmacokinetic Modeling: Non-Linear Mixed Effects Modeling.

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The Important Role that Biopharmaceutics Plays in Accelerating Early-Phase Drug Development

Pharmaceutical Technology

Quotient Sciences helps biotech and pharma customers in the development and optimization of drug products. Our chemists and formulation scientists review the properties of new drug candidates and “work their magic” to develop formulations that improve the exposure profile of the compound.

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The Composition and Value of a Portfolio Analysis

Camargo

One of Camargo’s differentiating offerings is the portfolio analysis, a high-level, integrated evaluation of the scientific, medical, regulatory, and commercial viability of each product within a sponsor’s portfolio. Each product is unique, and so is the associated development strategy. Why Conduct a Portfolio Analysis?

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Roquette opens pharmaceutical innovation facility in Pennsylvania, US

Pharmaceutical Technology

It also aims to contribute to the pharmaceutical sector by facilitating cross-industry partnerships and research-based product development. Roquette has appointed a new team of research scientists and formulation experts to offer guidance to the facility and to the company’s global pharmaceutical R&D activities.

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Solving pharma’s process development challenges one API at a time

Pharmaceutical Technology

The potential to use these scientific breakthroughs to make a real difference to patients’ lives is what drives many highly skilled scientists to the world of drug development. This is an exact science as the generation of too-fine or not-fine-enough powder will have a huge impact on the end-product.

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Strategies for Streamlining Small Molecule Formulation Development When Bridging from Candidate Selection to First-in-Human Clinical Testing

Pharmaceutical Technology

Quotient Sciences was asked to select the best candidate based on material science and oral bioavailability considerations. We select the appropriate salt or physical form to optimize a molecule for both manufacturability and downstream product performance.

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The New Frontier in Drug Development: Understanding Biologics and Small Molecules

Cloudbyz

The difference between biologics vs small molecules in pharma drug development In pharmaceutical drug development, biologics and small molecules represent two distinct categories of medicinal products, each with their own unique characteristics, development processes, and mechanisms of action.