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How PK Modeling Can Inform Sample Size Estimation and Dose Selection for Your Product

Camargo

The results of the population analysis reveal the average relative bioavailability of the test to reference. The comparison of relative bioavailability based on simulated data then indicates if BE can be achieved. Pharmacokinetics Scientist. Co-Authors: Galina Bernstein, PhD. Senior Director, Clinical Pharmacology. Pop-Pharm.

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Roquette opens pharmaceutical innovation facility in Pennsylvania, US

Pharmaceutical Technology

In the first phase of its training workshops, the Pharmaceutical Innovation Center plans to develop a range of excipients [inactive substances that serve as the vehicle or medium for a drug or other active substance] for controlled release dosage forms, improving their bioavailability, along with formulating orally dispersible and chewable tablets.

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Welsh startup Antiverse raises $2m for antibody discovery toolkit

pharmaphorum

Antiverse – which was co-founded in 2017 by engineers Murat Tunaboylu and Ben Holland – says it will use the cash injection to build a new laboratory in Cardiff and expand its technical team through recruitment of specialist machine learning engineers, laboratory scientists and structural biologists.

Antibody 101
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PROTACs show promise for cancer treatment

Pharmaceutical Technology

Syngene has more than seven years of experience with 450+ scientists working in targeted protein modulator (degraders and stabilizers) class, both in chemistry and biology under different collaborative projects. Syngene’s PROTAC capabilities put it at the forefront of developing novel protein degraders across a range of diseases.

Protein 130
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The Composition and Value of a Portfolio Analysis

Camargo

Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence. Scientist, Regulatory Strategy. Biowaiver Eligibility. These capabilities help sponsors to operate within the relevant regulatory framework to meet their goals.

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Solving pharma’s process development challenges one API at a time

Pharmaceutical Technology

The potential to use these scientific breakthroughs to make a real difference to patients’ lives is what drives many highly skilled scientists to the world of drug development. The discovery of a new chemical entity (NCE) that could potentially lead the way to a ground-breaking therapeutic treatment is an exciting prospect for any chemist.

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The New Frontier in Drug Development: Understanding Biologics and Small Molecules

Cloudbyz

Oral Bioavailability: Developing small molecules that are effectively absorbed when administered orally, while also being stable in the digestive system, can be complex. Enhancing bioavailability is often a key focus in the development of small molecule drugs.