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Alnylam finds belly fat gene and drug target in UK Biobank study

pharmaphorum

Alnylam Pharma has made a name for itself, developing gene-silencing therapies for rare disorders, but its latest discovery could take it into a much larger category – metabolic and cardiovascular disease. Transgenic mice in which the gene has been deleted have improved control of blood glucose and insulin sensitivity.

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Research Roundup: Blood Test for Severe COVID-19 and More

The Pharma Data

Four years ago, the University of Malta established a national ALS Registry and Biobank to identify ALS patients and collect data on their residence, occupation, lifestyle and environmental exposures. Specifically, the Malta patients did not have mutations in the C9orf72, SOD1, TARDBP and FUS genes.