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Can genetic data be a magic bullet for drug R&D?

pharmaphorum

Pharma has used this to begin creating targeted treatments, such as gene therapies , which are able to hone in on gene mutations that cause health issues and eradicate or replace the faulty gene. Scientists are able to study the aggregated, de-identified genetics of these individuals.

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New Research Reveals How Air Pollution May Trigger Lung Cancer

XTalks

Now, scientists have found a mechanism that may help explain how pollutants in the air can turn cells cancerous. Having a mutation in one copy of either the EGFR and/or KRAS gene isn’t enough to lead to lung cancer. The researchers propose that particulate matter 2.5 The Double Hit. Results of the investigations showed that PM 2.5

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Collaboration between AbbVie, Biogen and Pfizer creates world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease

The Pharma Data

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. About the UK Biobank. UK Biobank recruited 500,000 people aged between 40-69 years in 2006-2010 from across the UK.

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WORLD’S LARGEST BROWSABLE RESOURCE LINKING RARE PROTEIN-CODING GENETIC VARIANTS TO HUMAN HEALTH AND DISEASE

The Pharma Data

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. This browser will enable scientists worldwide to explore and utilize the data for their respective areas of interest in accordance with UK Biobank’s terms of use.

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Research Roundup: Blood Test for Severe COVID-19 and More

The Pharma Data

Four years ago, the University of Malta established a national ALS Registry and Biobank to identify ALS patients and collect data on their residence, occupation, lifestyle and environmental exposures. Specifically, the Malta patients did not have mutations in the C9orf72, SOD1, TARDBP and FUS genes.