pharmaphorum

JULY 28, 2022

. “We are currently testing this hypothesis, with the goal of pursuing a development candidate targeting INHBE in the near future,” said Paul Nioi, head of Alnylam’s human genetics group. The post Alnylam finds belly fat gene and drug target in UK Biobank study appeared first on.

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Scienmag

DECEMBER 7, 2021

The team also found certain genetic variants that were linked with these traits. The study included data on thousands of individuals from the UK Biobank. […].

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The Pharma Data

JULY 15, 2021

The access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. About the UK Biobank. Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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JAMA Internal Medicine

JULY 31, 2018

This population-based study of UK Biobank data assesses the association between coffee intake and mortality according to genetic caffeine metabolism scores.

Genetics 40

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The Pharma Data

JULY 8, 2021

Today, access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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pharmaphorum

JANUARY 26, 2023

We are already seeing an increase in projects exploring population genomics in Africa, the Middle East, and Asia, with initiatives including the GenomeAsia100K Project and the Genome Aggregation Database focusing on capturing genetic data of non-European individuals.

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Medical Xpress

MARCH 9, 2023

Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are also the leading cause of blindness certification in working-age adults.

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pharmaphorum

DECEMBER 2, 2021

Genetics, proteomics and digital pathology will be harnessed in order to understand the patterns of disease which vary amongst individuals, said GSK. ” The new institute will also draw on GSK’s partnerships with organisations, such as 23andMe and UK Biobank, that are a source of genetic information in diseases.

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Scienmag

JUNE 8, 2021

The research, which relied on data from the UK Biobank, the Early Growth Genetics consortium, and the Genetic Factors for Osteoporosis consortium, also found […].

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Cloudbyz

NOVEMBER 3, 2021

Automated Biobanking. Automated Biobanking is an approach to radically reduce the manual tasks involved in properly storing, labeling, authenticating, and monitoring samples, as well as increasing the ease of displaying much of their data values and making sample retrieval easier. Cost Recovery Fees for Biobanks.

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Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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The Pharma Data

JANUARY 14, 2021

Biobank that enrolled more than 500,000 Britons aged 40 to 69 years from 2006 to 2010. A polygenic risk score was built using independent genetic variants known to associate with smoking behavior; this score represents genetic susceptibility to smoking initiation. Acosta, M.D., percent had an SAH. and 1.74, respectively).

Genetics 52

Genetics Biobanking Medicine Research 52

XTalks

SEPTEMBER 16, 2022

Researchers at the Francis Crick Institute and University College London in the UK have found how air pollution can trigger the activation of cells with existing genetic mutations to form cancer. Results of the investigations showed that PM 2.5

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XTalks

APRIL 15, 2021

A 2015 study published in Nature Genetics found that the availability of human genetic data made investigational drugs twice as likely to pass pivotal trials and eventually be approved. Figure 1: The use of Mendelian randomization to validate genetic drug targets.

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Trialfacts

SEPTEMBER 12, 2024

Their work is driven by a profound understanding of disease biology and supported by advanced discovery platforms such as genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and various animal models.

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Roots Analysis

SEPTEMBER 18, 2023

While some biobanks ( especially non-clinical ones ) use mechanical freezers for storage, liquid nitrogen is one of the most reliable cryostorage mediums. If the cell structure is to remain intact, long-term storage of cell products needs cryopreservation at temperatures lower than -130°C.

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The Pharma Data

JULY 12, 2021

“This is mostly because drugs that work perfectly in preclinical inbred models, such as laboratory mice, that are genetically or otherwise identical to each other, don’t translate to patients in the clinic, where each individual and their disease is unique. HUMANOID Center of Research Excellence?(CoRE),

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The Pharma Data

NOVEMBER 4, 2020

Nasdaq: CNTG), a commercial-stage company focused on rare diseases that transforms real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies, announced today the opening of its walk-in COVID-19 testing facility at the newly opened Berlin Brandenburg Airport (BER). About CENTOGENE.

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pharmaphorum

JUNE 13, 2022

An analysis of images of the retina harvested from the UK Biobank resource suggests that it may be possible to identify individuals at risk of coronary artery disease by examining the pattern of blood vessels in the retina during an eye test. ” Image by Paul Diaconu from Pixabay .

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XTalks

FEBRUARY 4, 2021

Biobanks are used for the coordination of high-yield patient sample collection. Moreover, biobanks are no longer passive biorepositories for accrual of samples and serve a more utilitarian function in identifying and coordinating specific research cohorts for longitudinal and prospective studies. Biobanking Models.

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The Pharma Data

JANUARY 20, 2021

The UK biobank released a further dataset on COVID-19 positive patients consisting of ~4,000 confirmed COVID-19 infected patients in November 2020. As previously outlined, Genetic Technologies established the Germline Testing division following the strategic decision to offer hereditary testing for inherited cancer.

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The Pharma Data

JANUARY 21, 2021

Four years ago, the University of Malta established a national ALS Registry and Biobank to identify ALS patients and collect data on their residence, occupation, lifestyle and environmental exposures. They are now working to identify what genetic aberrations are causing ALS in about half of the Maltese patients.

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