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One common characteristic for most if not all biologics is the triggering of an immuneresponse or anti-drug antibodies. On the contrary, due to the complexity involved in comparing the structures of biologics, selecting the correct sampling times to prove bioequivalence for both PK and biomarkers is of primary importance.
It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immuneresponse in inflammatory diseases. Acer Therapeutics announced full enrollment of trial evaluating the bioequivalence of ACER-001 compared to Buphenyl (sodium phenylbutyrate) for urea cycle disorders.
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