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CancerVar: A New Bioinformatics Tool Developed for Clinical Interpretation of Cancer Mutations

XTalks

Millions of somatic cancer variants have been identified due to precision medicine and next-generation sequencing (NGS). On Saturday, researchers at the Children’s Hospital of Philadelphia (CHOP) have announced that they developed and launched a new bioinformatics software tool called CancerVar (cancer variant interpretation).

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Deluge of DNA changes drives progression of fatal melanomas

Scienmag

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

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The future of genomic medicine: can it fulfil its promises?

pharmaphorum

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. At that time, we thought this would be the holy grail for medicine. Now, however, the field is changing with respect to genomic medicine. This allows for much lengthier reads.

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USC researchers discover better way to identify DNA variants

Scienmag

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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DNA in fringe-lipped bat poop reveals unexpected eating habits

Scienmag

When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Credit: Illustration by Amy Koehler Poop is full of secrets. For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species.

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Accurate aging of wild animals thanks to first epigenetic clock for bats

Scienmag

UMD-led research identifies age-related changes to DNA and reveals longevity-related differences between bat species Credit: G. Tschapka A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. Wilkinson, G. Puechmaille, M.

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LabCorp Backs Resolution Bioscience’s Liquid Biopsy Test for NSCLC

XTalks

The liquid biopsy will therefore help personalize medicines for patients based on the molecular features of their disease. The test involves isolating circulating tumor DNA in the blood and sequencing it to look for relevant gene mutations.

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