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New approach to diagnosing genetic diseases using RNA sequencing increases yield

Scienmag

A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing. A new study from Baylor College of Medicine finds […].

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Genetic profiling of Lyme disease could bring new therapeutic targetsĀ 

Drug Discovery World

Researchers have identified 35 genes associated with long-term Lyme disease that could potentially be used as biomarkers to diagnose patients with the condition. . The findings, from the Icahn School of Medicine at Mount Sinai in New York and published in the journal Cell Reports Medicine , may also lead to new therapeutic targets.

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Breaking COVID-19ā€™s ā€˜clutchā€™ to stop its spread

Scienmag

Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine Credit: Scott Wiseman for Scripps Research JUPITER, FL – Sept.

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PanOmics: Advancing drug discovery

Drug Discovery World

To enable Evotecā€™s precision medicine approach, we have been building technology platforms that allow PanOmics or multi-omics data generation at an industrialised scale. Using classical bulk (deep) RNA-Seq on thousands of human blood and tissue samples, Evotec has been building a high-quality molecular patient database ā€“ E.MPD.

Drugs 52
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Key industry partnerships advancing drug discovery

Drug Discovery World

Otsuka Pharmaceutical and Ionis Pharmaceuticals Otsuka Pharmaceutical and RNA therapy company Ionis have entered into a licence agreement for Otsuka to acquire exclusive marketing rights to Ionis’ hereditary angioedema (HAE) drug candidate donidalorsen in Europe. His research focuses on immunotherapies for patients with breast cancer.

Drugs 52
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The microbiome in precision medicine

Drug Discovery World

An industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development. Research increasingly demonstrates that within each discrete microbial environment (e.g.,

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Looking ahead to AACRĀ Ā 

Drug Discovery World

She is being recognised for her longstanding commitment as a patient advocate for American Indian Tribes across the Mountain West and beyond, and for her commitment to improving health literacy and clinical trial enrolment among American Indian populations.

Protein 52